Synthesis of phenothiazine lead chloride perovskite quantum dots for fluorescence detection of dipicolinic acid in aqueous medium.

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Bibliographic Details
Title: Synthesis of phenothiazine lead chloride perovskite quantum dots for fluorescence detection of dipicolinic acid in aqueous medium.
Authors: Ghinaiya, Nirav Vajubhai1 (AUTHOR), Patel, Mayurkumar Revabhai1 (AUTHOR), Park, Tae Jung2 (AUTHOR), Kailasa, Suresh Kumar1 (AUTHOR) sureshkumarchem@gmail.com
Source: Microchimica Acta. Jun2025, Vol. 192 Issue 6, p1-10. 10p.
Subjects: Quantum dots, Phenothiazine, Detection limit, Analytical chemistry, Fluorescence, Solar cells
Abstract: Water-dispersible hybrid organic–inorganic perovskite quantum dots (QDs) were synthesized using phenothiazine (PTZ) as a capping agent. The PTZ capped lead chloride perovskite ((PTZ)PbCl3 QDs) acted as a probe for the fluorescence detection of dipicolinic acid (DPA) via a fluorescence "turn-off" mechanism. This work illustrates that (PTZ)PbCl3 QDs have strong affinity toward DPA, favoring to achieve a good linear range (5.0–40 μM) with a detection limit of 46.55 nM. Additionally, a portable (PTZ)PbCl3 QDs integrated paper-based analytical sensing device was fabricated for fluorescence readout assay of DPA, revealing its potential for assaying of DPA with simplified analytical procedure. Furthermore, the developed (PTZ)PbCl3 QDs integrated fluorescence spectrometric method was successfully applied to assay DPA in human serum samples. This approach serves as a promising analytical platform for detecting DPA in biofluids, offering a simple and efficient analytical sensing method for real sample analysis. [ABSTRACT FROM AUTHOR]
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Database: Engineering Source
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Abstract:Water-dispersible hybrid organic–inorganic perovskite quantum dots (QDs) were synthesized using phenothiazine (PTZ) as a capping agent. The PTZ capped lead chloride perovskite ((PTZ)PbCl3 QDs) acted as a probe for the fluorescence detection of dipicolinic acid (DPA) via a fluorescence "turn-off" mechanism. This work illustrates that (PTZ)PbCl3 QDs have strong affinity toward DPA, favoring to achieve a good linear range (5.0–40 μM) with a detection limit of 46.55 nM. Additionally, a portable (PTZ)PbCl3 QDs integrated paper-based analytical sensing device was fabricated for fluorescence readout assay of DPA, revealing its potential for assaying of DPA with simplified analytical procedure. Furthermore, the developed (PTZ)PbCl3 QDs integrated fluorescence spectrometric method was successfully applied to assay DPA in human serum samples. This approach serves as a promising analytical platform for detecting DPA in biofluids, offering a simple and efficient analytical sensing method for real sample analysis. [ABSTRACT FROM AUTHOR]
ISSN:00263672
DOI:10.1007/s00604-025-07215-9