View in EDS

A facile aptasensor based on Au dimers and carbon dots for SERS/fluorescence dual-mode detection of AFB1.

Saved in:
Bibliographic Details
Title: A facile aptasensor based on Au dimers and carbon dots for SERS/fluorescence dual-mode detection of AFB1.
Authors: Gao, Xueying1,2,3,4 (AUTHOR), Wang, Luning1,2,3,4 (AUTHOR), Chen, Yi1,2,3,4 (AUTHOR), Ma, Xi1,2,3,4 (AUTHOR), Hui, Minyi1,2,3,4 (AUTHOR), Wang, Zhouping1,2,3,4 (AUTHOR), Ma, Xiaoyuan1,2,3,4 (AUTHOR) maxy@jiangnan.edu.cn
Source: Sensors & Actuators B: Chemical. Nov2025, Vol. 443, pN.PAG-N.PAG. 1p.
Subjects: Aflatoxins, SERS spectroscopy, Fluorescence, Detection limit, Carbon nanodots, Gold nanoparticles, Empirical research, Biosensors
Abstract: A dual-signal aptasensor that integrates Surface-Enhanced Raman Scattering (SERS) and fluorescence has been developed for the sensitive detection of aflatoxin B 1 (AFB 1). 2,2′-bipyridine ethylene (BPE) linked to gold nanoparticles (AuNPs) through "Au-N" bonds formed Au dimers with nanogaps. These were functionalized with complementary DNA (cDNA) of the AFB 1 apt, serving as both a Raman signal probe and a fluorescence quencher. The Fe 3 O 4 @SiO 2 -carbon dots (CDs), modified with the AFB 1 apt, functioned as a fluorescent magnetic substrate facilitating efficient separation. The components assembled into a satellite-like structure, which maximized SERS signals while simultaneously quenching fluorescence. Upon the addition of AFB 1 , the Raman probe was released, leading to a reduction in SERS signals and recovery of fluorescence. The sensor demonstrated an extensive linear detection range from 10⁻⁴ to 10² ng/mL, accompanied by an ultra-low limit of detection (LOD) of 0.066 pg/kg. Spiked recovery rates in peanut, rice, and corn samples ranged from 100.35 % to 109.75 %, indicating high accuracy and applicability for AFB 1 detection in real-world samples. [Display omitted] • Dual-signal AFB 1 detection was realized via LSPR, FRET, and FDQ integration. • Au dimers showed strong SERS enhancement and effective fluorescence quenching. • Fe 3 O 4 @SiO 2 -CDs enabled efficient separation and stable fluorescence. • The aptasensor exhibited high selectivity toward AFB 1. • AFB 1 detection limit reached 0.066 pg/mL, with high accuracy in real samples. [ABSTRACT FROM AUTHOR]
Copyright of Sensors & Actuators B: Chemical is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
FullText Text:
  Availability: 0
Header DbId: egs
DbLabel: Engineering Source
An: 187113761
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: A facile aptasensor based on Au dimers and carbon dots for SERS/fluorescence dual-mode detection of AFB1.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Gao%2C+Xueying%22">Gao, Xueying</searchLink><relatesTo>1,2,3,4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wang%2C+Luning%22">Wang, Luning</searchLink><relatesTo>1,2,3,4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chen%2C+Yi%22">Chen, Yi</searchLink><relatesTo>1,2,3,4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ma%2C+Xi%22">Ma, Xi</searchLink><relatesTo>1,2,3,4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hui%2C+Minyi%22">Hui, Minyi</searchLink><relatesTo>1,2,3,4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wang%2C+Zhouping%22">Wang, Zhouping</searchLink><relatesTo>1,2,3,4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ma%2C+Xiaoyuan%22">Ma, Xiaoyuan</searchLink><relatesTo>1,2,3,4</relatesTo> (AUTHOR)<i> maxy@jiangnan.edu.cn</i>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Sensors+%26+Actuators+B%3A+Chemical%22">Sensors & Actuators B: Chemical</searchLink>. Nov2025, Vol. 443, pN.PAG-N.PAG. 1p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Aflatoxins%22">Aflatoxins</searchLink><br /><searchLink fieldCode="DE" term="%22SERS+spectroscopy%22">SERS spectroscopy</searchLink><br /><searchLink fieldCode="DE" term="%22Fluorescence%22">Fluorescence</searchLink><br /><searchLink fieldCode="DE" term="%22Detection+limit%22">Detection limit</searchLink><br /><searchLink fieldCode="DE" term="%22Carbon+nanodots%22">Carbon nanodots</searchLink><br /><searchLink fieldCode="DE" term="%22Gold+nanoparticles%22">Gold nanoparticles</searchLink><br /><searchLink fieldCode="DE" term="%22Empirical+research%22">Empirical research</searchLink><br /><searchLink fieldCode="DE" term="%22Biosensors%22">Biosensors</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: A dual-signal aptasensor that integrates Surface-Enhanced Raman Scattering (SERS) and fluorescence has been developed for the sensitive detection of aflatoxin B 1 (AFB 1). 2,2′-bipyridine ethylene (BPE) linked to gold nanoparticles (AuNPs) through "Au-N" bonds formed Au dimers with nanogaps. These were functionalized with complementary DNA (cDNA) of the AFB 1 apt, serving as both a Raman signal probe and a fluorescence quencher. The Fe 3 O 4 @SiO 2 -carbon dots (CDs), modified with the AFB 1 apt, functioned as a fluorescent magnetic substrate facilitating efficient separation. The components assembled into a satellite-like structure, which maximized SERS signals while simultaneously quenching fluorescence. Upon the addition of AFB 1 , the Raman probe was released, leading to a reduction in SERS signals and recovery of fluorescence. The sensor demonstrated an extensive linear detection range from 10⁻⁴ to 10² ng/mL, accompanied by an ultra-low limit of detection (LOD) of 0.066 pg/kg. Spiked recovery rates in peanut, rice, and corn samples ranged from 100.35 % to 109.75 %, indicating high accuracy and applicability for AFB 1 detection in real-world samples. [Display omitted] • Dual-signal AFB 1 detection was realized via LSPR, FRET, and FDQ integration. • Au dimers showed strong SERS enhancement and effective fluorescence quenching. • Fe 3 O 4 @SiO 2 -CDs enabled efficient separation and stable fluorescence. • The aptasensor exhibited high selectivity toward AFB 1. • AFB 1 detection limit reached 0.066 pg/mL, with high accuracy in real samples. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Sensors & Actuators B: Chemical is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=187113761
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.snb.2025.138297
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 1
        StartPage: N.PAG
    Subjects:
      – SubjectFull: Aflatoxins
        Type: general
      – SubjectFull: SERS spectroscopy
        Type: general
      – SubjectFull: Fluorescence
        Type: general
      – SubjectFull: Detection limit
        Type: general
      – SubjectFull: Carbon nanodots
        Type: general
      – SubjectFull: Gold nanoparticles
        Type: general
      – SubjectFull: Empirical research
        Type: general
      – SubjectFull: Biosensors
        Type: general
    Titles:
      – TitleFull: A facile aptasensor based on Au dimers and carbon dots for SERS/fluorescence dual-mode detection of AFB1.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Gao, Xueying
      – PersonEntity:
          Name:
            NameFull: Wang, Luning
      – PersonEntity:
          Name:
            NameFull: Chen, Yi
      – PersonEntity:
          Name:
            NameFull: Ma, Xi
      – PersonEntity:
          Name:
            NameFull: Hui, Minyi
      – PersonEntity:
          Name:
            NameFull: Wang, Zhouping
      – PersonEntity:
          Name:
            NameFull: Ma, Xiaoyuan
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 15
              M: 11
              Text: Nov2025
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-print
              Value: 09254005
          Numbering:
            – Type: volume
              Value: 443
          Titles:
            – TitleFull: Sensors & Actuators B: Chemical
              Type: main
ResultId 1