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Sensitivity Enhancement of Plasmonic Biosensor for Glucose Level Detection Using Black Phosphorus and Copper-Based Multilayer Design.

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Title: Sensitivity Enhancement of Plasmonic Biosensor for Glucose Level Detection Using Black Phosphorus and Copper-Based Multilayer Design.
Authors: Mohadesi, Vahideh1 (AUTHOR) v.mohadesi@gmail.com
Source: Plasmonics. Oct2025, Vol. 20 Issue 10, p8537-8546. 10p.
Subjects: Blood sugar monitoring, Surface plasmon resonance, Multilayers, Routine diagnostic tests, Biosensors, Phosphorene, Sensitivity analysis
Abstract: This study presents a novel optimization of a surface plasmon resonance (SPR) biosensor for non-invasive glucose detection in urine. By incorporating a multilayer structure comprising a cesium fluoride (CsF) prism, a copper (Cu) plasmonic layer, a halide perovskite (FASnI₃) layer, and 1–6 layers of black phosphorus (BP), the biosensor achieves exceptional performance metrics. Systematic analysis reveals that a five-layer BP configuration optimally enhances electromagnetic field confinement, yielding a sensitivity exceeding 500°/RIU and a quality factor above 140, significantly surpassing conventional SPR designs. The proposed design leverages the cost-effectiveness of Cu as an alternative to precious metals and the advanced optical properties of BP, establishing a superior diagnostic tool for precise, real-time glucose monitoring. This research lays a foundation for next-generation biosensors, offering high sensitivity, reduced costs, and versatile applications in healthcare diagnostics. [ABSTRACT FROM AUTHOR]
Copyright of Plasmonics is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Sensitivity Enhancement of Plasmonic Biosensor for Glucose Level Detection Using Black Phosphorus and Copper-Based Multilayer Design.
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  Data: <searchLink fieldCode="AR" term="%22Mohadesi%2C+Vahideh%22">Mohadesi, Vahideh</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> v.mohadesi@gmail.com</i>
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  Data: <searchLink fieldCode="JN" term="%22Plasmonics%22">Plasmonics</searchLink>. Oct2025, Vol. 20 Issue 10, p8537-8546. 10p.
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  Data: <searchLink fieldCode="DE" term="%22Blood+sugar+monitoring%22">Blood sugar monitoring</searchLink><br /><searchLink fieldCode="DE" term="%22Surface+plasmon+resonance%22">Surface plasmon resonance</searchLink><br /><searchLink fieldCode="DE" term="%22Multilayers%22">Multilayers</searchLink><br /><searchLink fieldCode="DE" term="%22Routine+diagnostic+tests%22">Routine diagnostic tests</searchLink><br /><searchLink fieldCode="DE" term="%22Biosensors%22">Biosensors</searchLink><br /><searchLink fieldCode="DE" term="%22Phosphorene%22">Phosphorene</searchLink><br /><searchLink fieldCode="DE" term="%22Sensitivity+analysis%22">Sensitivity analysis</searchLink>
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  Label: Abstract
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  Data: This study presents a novel optimization of a surface plasmon resonance (SPR) biosensor for non-invasive glucose detection in urine. By incorporating a multilayer structure comprising a cesium fluoride (CsF) prism, a copper (Cu) plasmonic layer, a halide perovskite (FASnI₃) layer, and 1–6 layers of black phosphorus (BP), the biosensor achieves exceptional performance metrics. Systematic analysis reveals that a five-layer BP configuration optimally enhances electromagnetic field confinement, yielding a sensitivity exceeding 500°/RIU and a quality factor above 140, significantly surpassing conventional SPR designs. The proposed design leverages the cost-effectiveness of Cu as an alternative to precious metals and the advanced optical properties of BP, establishing a superior diagnostic tool for precise, real-time glucose monitoring. This research lays a foundation for next-generation biosensors, offering high sensitivity, reduced costs, and versatile applications in healthcare diagnostics. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: <i>Copyright of Plasmonics is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1007/s11468-025-02896-7
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        Text: English
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      – SubjectFull: Blood sugar monitoring
        Type: general
      – SubjectFull: Surface plasmon resonance
        Type: general
      – SubjectFull: Multilayers
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      – SubjectFull: Routine diagnostic tests
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      – SubjectFull: Biosensors
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      – SubjectFull: Phosphorene
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      – SubjectFull: Sensitivity analysis
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              Text: Oct2025
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