Sensitivity Enhancement of Plasmonic Biosensor for Glucose Level Detection Using Black Phosphorus and Copper-Based Multilayer Design.

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Title: Sensitivity Enhancement of Plasmonic Biosensor for Glucose Level Detection Using Black Phosphorus and Copper-Based Multilayer Design.
Authors: Mohadesi, Vahideh1 (AUTHOR) v.mohadesi@gmail.com
Source: Plasmonics. Oct2025, Vol. 20 Issue 10, p8537-8546. 10p.
Subjects: Blood sugar monitoring, Surface plasmon resonance, Multilayers, Routine diagnostic tests, Biosensors, Phosphorene, Sensitivity analysis
Abstract: This study presents a novel optimization of a surface plasmon resonance (SPR) biosensor for non-invasive glucose detection in urine. By incorporating a multilayer structure comprising a cesium fluoride (CsF) prism, a copper (Cu) plasmonic layer, a halide perovskite (FASnI₃) layer, and 1–6 layers of black phosphorus (BP), the biosensor achieves exceptional performance metrics. Systematic analysis reveals that a five-layer BP configuration optimally enhances electromagnetic field confinement, yielding a sensitivity exceeding 500°/RIU and a quality factor above 140, significantly surpassing conventional SPR designs. The proposed design leverages the cost-effectiveness of Cu as an alternative to precious metals and the advanced optical properties of BP, establishing a superior diagnostic tool for precise, real-time glucose monitoring. This research lays a foundation for next-generation biosensors, offering high sensitivity, reduced costs, and versatile applications in healthcare diagnostics. [ABSTRACT FROM AUTHOR]
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Database: Engineering Source
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