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Indoor Dampness and Molds and Development of Adult-Onset Asthma: A Population-Based Incident Case-Control Study.

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Title: Indoor Dampness and Molds and Development of Adult-Onset Asthma: A Population-Based Incident Case-Control Study.
Authors: Jaakkola, Maritta S., Nordman, Henrik, Piipari, Ritva, Uitti, Jukka, Laitinen, Jukka, Karjalainen, Antti, Hahtola, Paula, Jaakkola, Jouni J.K.
Source: Environmental Health Perspectives. May2002, Vol. 110 Issue 5, p543. 5p. 5 Charts.
Subjects: Asthma, Dampness in buildings, Logistic regression analysis
Abstract: Previous cross-sectional and prevalent case—control studies have suggested increased risk of asthma in adults related to dampness problems and molds in homes. We conducted a population-based incident case—control study to assess the effects of indoor dampness problems and molds at work and at home on development of asthma in adults. We recruited systematically all new cases of asthma during a 2.5-year study period (997–2000) and randomly selected controls from a source population consisting of adults 21–63 years old living in the Pirkanmaa Hospital district, South Finland. The clinically diagnosed case series consisted of 521 adults with newly diagnosed asthma and the control series of 932 controls, after we excluded 76 (7.5%) controls with a history of asthma. In logistic regression analysis adjusting for confounders, the risk of asthma was related to the presence of visible mold and/or mold odor in the workplace (odds ratio, 1.54; 95% confidence interval, 1.01–2.32) but not to water damage or damp stains alone. We estimated the fraction of asthma attributable to workplace mold exposure to be 35.1% (95% confidence interval, 1.0–56.9%) among the exposed. Present results provide new evidence of the relation between workplace exposure to indoor molds and adult-onset asthma. Key words: asthma, case—control study, molds, occupational exposure, population-based. Environ Health Perspect 110:543–547 (2002). [Online 4 April 2002] http://ehpnet1.niehs.nih.gov/docs/2002/110p543-547jaakkola/abstr act.html [ABSTRACT FROM AUTHOR]
Copyright of Environmental Health Perspectives is the property of National Institute of Environmental Health Sciences and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Previous cross-sectional and prevalent case—control studies have suggested increased risk of asthma in adults related to dampness problems and molds in homes. We conducted a population-based incident case—control study to assess the effects of indoor dampness problems and molds at work and at home on development of asthma in adults. We recruited systematically all new cases of asthma during a 2.5-year study period (997–2000) and randomly selected controls from a source population consisting of adults 21–63 years old living in the Pirkanmaa Hospital district, South Finland. The clinically diagnosed case series consisted of 521 adults with newly diagnosed asthma and the control series of 932 controls, after we excluded 76 (7.5%) controls with a history of asthma. In logistic regression analysis adjusting for confounders, the risk of asthma was related to the presence of visible mold and/or mold odor in the workplace (odds ratio, 1.54; 95% confidence interval, 1.01–2.32) but not to water damage or damp stains alone. We estimated the fraction of asthma attributable to workplace mold exposure to be 35.1% (95% confidence interval, 1.0–56.9%) among the exposed. Present results provide new evidence of the relation between workplace exposure to indoor molds and adult-onset asthma. Key words: asthma, case—control study, molds, occupational exposure, population-based. Environ Health Perspect 110:543–547 (2002). [Online 4 April 2002] http://ehpnet1.niehs.nih.gov/docs/2002/110p543-547jaakkola/abstr act.html [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Environmental Health Perspectives is the property of National Institute of Environmental Health Sciences and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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