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Optimization of compactin production in chemically defined production medium by Penicillium citrinum using statistical methods

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Title: Optimization of compactin production in chemically defined production medium by Penicillium citrinum using statistical methods
Authors: Chakravarti, R.1, Sahai, V. vikramsahai@hotmail.com
Source: Process Biochemistry. Dec2002, Vol. 38 Issue 4, p481. 6p.
Subjects: Penicillium, Fungi imperfecti
Abstract: Production of compactin by Penicillium citrinum was optimized using Plackett–Burman and central composite rotatable design. Out of 11 factors studied by Plackett–Burman design, six influenced the compactin production. Central composite rotatable design was used to optimize the significant factors and response surface plots were generated. Using these response surface plots and point prediction, optimized values of the factors were determined and a maximum compactin production of 490 mg/l was predicted. An experimental study using the optimized parameters resulted in production of 456 mg compactin per l, 93% of the predicted value. [Copyright &y& Elsevier]
Copyright of Process Biochemistry is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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Header DbId: egs
DbLabel: Engineering Source
An: 7917725
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Optimization of compactin production in chemically defined production medium by Penicillium citrinum using statistical methods
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  Data: <searchLink fieldCode="AR" term="%22Chakravarti%2C+R%2E%22">Chakravarti, R.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Sahai%2C+V%2E%22">Sahai, V.</searchLink><i> vikramsahai@hotmail.com</i>
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  Data: <searchLink fieldCode="JN" term="%22Process+Biochemistry%22">Process Biochemistry</searchLink>. Dec2002, Vol. 38 Issue 4, p481. 6p.
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  Data: <searchLink fieldCode="DE" term="%22Penicillium%22">Penicillium</searchLink><br /><searchLink fieldCode="DE" term="%22Fungi+imperfecti%22">Fungi imperfecti</searchLink>
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  Data: Production of compactin by Penicillium citrinum was optimized using Plackett–Burman and central composite rotatable design. Out of 11 factors studied by Plackett–Burman design, six influenced the compactin production. Central composite rotatable design was used to optimize the significant factors and response surface plots were generated. Using these response surface plots and point prediction, optimized values of the factors were determined and a maximum compactin production of 490 mg/l was predicted. An experimental study using the optimized parameters resulted in production of 456 mg compactin per l, 93% of the predicted value. [Copyright &y& Elsevier]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Process Biochemistry is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1016/S0032-9592(02)00138-3
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      – Code: eng
        Text: English
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        PageCount: 6
        StartPage: 481
    Subjects:
      – SubjectFull: Penicillium
        Type: general
      – SubjectFull: Fungi imperfecti
        Type: general
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      – TitleFull: Optimization of compactin production in chemically defined production medium by Penicillium citrinum using statistical methods
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              Text: Dec2002
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              Y: 2002
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              Value: 38
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