View in EDS

Experimental Flow Studies in Exact-Replica Phantoms of Atherosclerotic Carotid Bifurcations Under Steady Input Conditions.

Saved in:
Bibliographic Details
Title: Experimental Flow Studies in Exact-Replica Phantoms of Atherosclerotic Carotid Bifurcations Under Steady Input Conditions.
Authors: Bale-Glickman, B., Selby, K., Saloner, D., Savaş, Ö.
Source: Journal of Biomechanical Engineering. Feb2003, Vol. 125 Issue 1, p38. 11p. 47 Black and White Photographs, 1 Diagram, 2 Graphs.
Subjects: Blood flow, Carotid artery, Atherosclerosis
Abstract: Extensive flow studies are conducted in two carotid bifurcation flow phantoms. These phantoms exactly replicate the lumen of the plaque excised intact from two patients with severe carotid atherosclerosis. The input flow into the phantom's common carotid artery is steady. Novel scanning techniques for flow visualization and particle image velocimetry are used. In addition, a novel boundary treatment technique is employed in velocimetry to extract first order accurate velocity gradients at walls. The data show that the flow fields are highly three-dimensional. Numerous separation and recirculation zones dominate the flow domain, except at the lowest Reynolds numbers. The separation regions are often so severe that highly directed internal jets form. At high Reynolds numbers, the flows become unsteady and chaotic, even though the input flow is steady. Flow fields have large regions of energetic flow and almost stagnant recirculation zones. These recirculation zones range in size from the full size of the arteries to zones within crevasses smaller than 1 mm. Velocity field and streamline patterns conform well to the lumen geometry. The streamlines are highly tortuous. Stagnation points correlate well with the topological features of the stenosis. Vorticity maps confirm the highly complex and three dimensional nature of the flow. Wall shear stresses at the stenoses are estimated to be on the order of 10 Pa. These studies conclusively show that the nature of the flow in the diseased bifurcation is primarily dictated by the lumen geometry. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Biomechanical Engineering is the property of American Society of Mechanical Engineers and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
FullText Text:
  Availability: 0
Header DbId: egs
DbLabel: Engineering Source
An: 9313292
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Experimental Flow Studies in Exact-Replica Phantoms of Atherosclerotic Carotid Bifurcations Under Steady Input Conditions.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Bale-Glickman%2C+B%2E%22">Bale-Glickman, B.</searchLink><br /><searchLink fieldCode="AR" term="%22Selby%2C+K%2E%22">Selby, K.</searchLink><br /><searchLink fieldCode="AR" term="%22Saloner%2C+D%2E%22">Saloner, D.</searchLink><br /><searchLink fieldCode="AR" term="%22Savaş%2C+Ö%2E%22">Savaş, Ö.</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Journal+of+Biomechanical+Engineering%22">Journal of Biomechanical Engineering</searchLink>. Feb2003, Vol. 125 Issue 1, p38. 11p. 47 Black and White Photographs, 1 Diagram, 2 Graphs.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Blood+flow%22">Blood flow</searchLink><br /><searchLink fieldCode="DE" term="%22Carotid+artery%22">Carotid artery</searchLink><br /><searchLink fieldCode="DE" term="%22Atherosclerosis%22">Atherosclerosis</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Extensive flow studies are conducted in two carotid bifurcation flow phantoms. These phantoms exactly replicate the lumen of the plaque excised intact from two patients with severe carotid atherosclerosis. The input flow into the phantom's common carotid artery is steady. Novel scanning techniques for flow visualization and particle image velocimetry are used. In addition, a novel boundary treatment technique is employed in velocimetry to extract first order accurate velocity gradients at walls. The data show that the flow fields are highly three-dimensional. Numerous separation and recirculation zones dominate the flow domain, except at the lowest Reynolds numbers. The separation regions are often so severe that highly directed internal jets form. At high Reynolds numbers, the flows become unsteady and chaotic, even though the input flow is steady. Flow fields have large regions of energetic flow and almost stagnant recirculation zones. These recirculation zones range in size from the full size of the arteries to zones within crevasses smaller than 1 mm. Velocity field and streamline patterns conform well to the lumen geometry. The streamlines are highly tortuous. Stagnation points correlate well with the topological features of the stenosis. Vorticity maps confirm the highly complex and three dimensional nature of the flow. Wall shear stresses at the stenoses are estimated to be on the order of 10 Pa. These studies conclusively show that the nature of the flow in the diseased bifurcation is primarily dictated by the lumen geometry. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Journal of Biomechanical Engineering is the property of American Society of Mechanical Engineers and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=9313292
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1115/1.1537734
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 11
        StartPage: 38
    Subjects:
      – SubjectFull: Blood flow
        Type: general
      – SubjectFull: Carotid artery
        Type: general
      – SubjectFull: Atherosclerosis
        Type: general
    Titles:
      – TitleFull: Experimental Flow Studies in Exact-Replica Phantoms of Atherosclerotic Carotid Bifurcations Under Steady Input Conditions.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Bale-Glickman, B.
      – PersonEntity:
          Name:
            NameFull: Selby, K.
      – PersonEntity:
          Name:
            NameFull: Saloner, D.
      – PersonEntity:
          Name:
            NameFull: Savaş, Ö.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 02
              Text: Feb2003
              Type: published
              Y: 2003
          Identifiers:
            – Type: issn-print
              Value: 01480731
          Numbering:
            – Type: volume
              Value: 125
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Journal of Biomechanical Engineering
              Type: main
ResultId 1