L-selectin activates the Ras pathway via the tyrosine kinase p56lck.
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| Title: | L-selectin activates the Ras pathway via the tyrosine kinase p56lck. |
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| Authors: | Brenner, B., Gulbins, E. |
| Source: | Proceedings of the National Academy of Sciences of the United States of America. 12/24/96, Vol. 93 Issue 26, p15376. 6p. 31 Black and White Photographs, 2 Graphs. |
| Subjects: | Cellular signal transduction, T cells, Gene transfection |
| Abstract: | Describes intracellular signaling events upon L-selectin triggering in T-lymphocyte lines, peripheral blood lymphocytes (PBL) and L-selectin transfectants. Tyrosine phosphorylation triggered by L-selectin; Induction of tyrosin phosphorylation by stimulation via L-selectin; Ras pathway stimulated by L-selectin. |
| Database: | Engineering Source |
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