Nocturia is Associated with High Atherosclerotic Cardiovascular Disease Risk in Women: Results from the National Health and Nutrition Examination Survey.

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Title: Nocturia is Associated with High Atherosclerotic Cardiovascular Disease Risk in Women: Results from the National Health and Nutrition Examination Survey.
Authors: Lazar, Jason M.1 Jason.Lazar@downstate.edu, Chobufo, Muchi Ditah2, Weiss, Jeffrey P.3, Everaert, Karel4, De Backer, Tine5, Wein, Alan J.6, Brunicardi, F. Charles7, Monaghan, Thomas F.3
Source: Journal of Community Health. Aug2021, Vol. 46 Issue 4, p854-860. 7p. 4 Charts.
Subject Terms: Atherosclerosis risk factors, Cardiovascular diseases risk factors, Statistics, Confidence intervals, Urination disorders, Multivariate analysis, Risk assessment, Surveys, Sex distribution, Questionnaires, Disease prevalence, Descriptive statistics, Logistic regression analysis, Odds ratio, Women's health, Probability theory, Disease complications
Geographic Terms: United States
Abstract: Growing evidence has identified nocturia as a potential manifestation of several cardiovascular disease states. We aimed to determine whether a relationship exists between nocturia and global atherosclerotic cardiovascular disease (ASCVD) risk, defined by the American College of Cardiology/American Heart Association (ACC/AHA) ASCVD risk calculator, using a large nationally-representative study sample from the United States. We explored potential associations between nocturia and ASCVD risk in adults aged 40–79 years with no prior history of overt/known atherosclerotic disease from 7 consecutive cycles of the National Health and Nutrition Examination Survey. Subjects were classified by whether they met the ASCVD high-risk threshold following current ACC/AHA consensus guidelines (10-year major adverse cardiovascular event risk ≥ 20%). Logistic regression analyses were used to explore associations between nocturia (defined as ≥ 2 nocturnal voids) and ASCVD risk. The prevalence of nocturia and high ASCVD risk were 27.0% and 10.9%, respectively. Nocturia, older age, increased body mass index, and diuretic use were associated with high ASCVD risk on univariate logistic regression. After adjusting for age, body mass index, and diuretic use, nocturia remained associated with significantly greater odds of high ASCVD risk in females but not in males. Elicitation of nocturia on clinical history taking may serve to identify high cardiovascular risk in females. Future studies are needed to elucidate mechanisms underlying this association. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Community Health is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Nocturia is Associated with High Atherosclerotic Cardiovascular Disease Risk in Women: Results from the National Health and Nutrition Examination Survey.
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Community+Health%22">Journal of Community Health</searchLink>. Aug2021, Vol. 46 Issue 4, p854-860. 7p. 4 Charts.
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  Data: Growing evidence has identified nocturia as a potential manifestation of several cardiovascular disease states. We aimed to determine whether a relationship exists between nocturia and global atherosclerotic cardiovascular disease (ASCVD) risk, defined by the American College of Cardiology/American Heart Association (ACC/AHA) ASCVD risk calculator, using a large nationally-representative study sample from the United States. We explored potential associations between nocturia and ASCVD risk in adults aged 40–79 years with no prior history of overt/known atherosclerotic disease from 7 consecutive cycles of the National Health and Nutrition Examination Survey. Subjects were classified by whether they met the ASCVD high-risk threshold following current ACC/AHA consensus guidelines (10-year major adverse cardiovascular event risk ≥ 20%). Logistic regression analyses were used to explore associations between nocturia (defined as ≥ 2 nocturnal voids) and ASCVD risk. The prevalence of nocturia and high ASCVD risk were 27.0% and 10.9%, respectively. Nocturia, older age, increased body mass index, and diuretic use were associated with high ASCVD risk on univariate logistic regression. After adjusting for age, body mass index, and diuretic use, nocturia remained associated with significantly greater odds of high ASCVD risk in females but not in males. Elicitation of nocturia on clinical history taking may serve to identify high cardiovascular risk in females. Future studies are needed to elucidate mechanisms underlying this association. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Journal of Community Health is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1007/s10900-021-00962-9
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        Text: English
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    Subjects:
      – SubjectFull: Atherosclerosis risk factors
        Type: general
      – SubjectFull: Cardiovascular diseases risk factors
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      – SubjectFull: Statistics
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      – SubjectFull: Confidence intervals
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      – SubjectFull: Urination disorders
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      – SubjectFull: Multivariate analysis
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      – SubjectFull: Risk assessment
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      – SubjectFull: Sex distribution
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      – SubjectFull: United States
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      – TitleFull: Nocturia is Associated with High Atherosclerotic Cardiovascular Disease Risk in Women: Results from the National Health and Nutrition Examination Survey.
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              Text: Aug2021
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