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Effectiveness of a Remote Physical Activity Intervention in Individuals with Alzheimer's Disease and their Caregivers: Results from a Randomized Trial.

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Title: Effectiveness of a Remote Physical Activity Intervention in Individuals with Alzheimer's Disease and their Caregivers: Results from a Randomized Trial.
Authors: PTOMEY, LAUREN T.1 (AUTHOR) lptomey@kumc.edu, HELSEL, BRIAN C.2 (AUTHOR), MONTGOMERY, ROBERT N.3 (AUTHOR), WASHBURN, RICHARD A.1 (AUTHOR), SHERMAN, JOSEPH R.1 (AUTHOR), SZABO-REED, AMANDA N.1 (AUTHOR), VIDONI, ERIC D.2 (AUTHOR), GORCZYCA, ANNA M.1 (AUTHOR), BODDE, AMY1 (AUTHOR), CLINA, JULIANNE G.1 (AUTHOR), WILLIAMS, KRISTINE N.4 (AUTHOR), DONNELLY, JOSEPH E.1 (AUTHOR)
Source: Medicine & Science in Sports & Exercise. Jul2026, Vol. 58 Issue 7, p1388-1398. 11p.
Subject Terms: *Caregivers, *Physical fitness, Patient compliance, Statistical models, Repeated measures design, Rehabilitation of Alzheimer's patients, Independent living, Research funding, Exercise therapy, Statistical sampling, Questionnaires, Sedentary lifestyles, Treatment effectiveness, Telerehabilitation, Randomized controlled trials, Severity of illness index, Exercise intensity, Descriptive statistics, Wearable technology, Actigraphy, Analysis of covariance, Muscle strength, Videoconferencing, Medical records, Data analysis software, Calorimetry, Oxygen consumption, Physical activity
Abstract: PTOMEY L. T., B. C. HELSEL, R. N. MONTGOMERY, R. A. WASHBURN, J. R. SHERMAN, A. N. SZABO-REED, E. D. VIDONI, A. M. GORCZYCA, A. BODDE, J. G. CLINA, K. N. WILLIAMS, and J. E. DONNELLY. Effectiveness of a Remote Physical Activity Intervention in Individuals with Alzheimer's Disease and their Caregivers: Results from a Randomized Trial. Med. Sci. Sports Exerc., Vol. 58, No. 7, pp. 1388–1398, 2026. Purpose: Individuals with Alzheimer's disease and related dementias (ADRD) and their caregivers often experience reduced physical activity (PA), diminished functional fitness, and heightened health risks. Remotely delivered PA interventions may offer scalable and accessible solutions. This study compared a 6-month, group-based dyadic PA program delivered via real-time group videoconferencing (RGV) with an enhanced usual care (EUC) condition on changes in moderate-to-vigorous physical activity (MVPA) and functional fitness among dyads consisting of individuals with ADRD and their caregivers. Methods: Dyads were randomized to either the RGV or EUC arm. Both arms received wearable activity trackers and twice-monthly individualized support. The RGV group additionally participated in live, thrice-weekly group exercise sessions via videoconference. Outcomes included accelerometer-assessed MVPA and standardized measures of functional fitness. Results: Ninety-nine dyads enrolled, with 90% retention at 6 months. Mean session attendance in the RGV arm was 74% for individuals with ADRD and 69.5% for caregivers. Neither group significantly increased daily MVPA, and there were no significant between-group differences in changes in daily MVPA or sedentary time (all P > 0.05). However, significant within-group improvements occurred in upper-body strength (arm curls) and aerobic capacity (2-minute step test) for both individuals with ADRD and caregivers (all P < 0.05). Compared with EUC, the RGV group showed greater improvements in aerobic capacity among individuals with ADRD (β = 8.97, P = 0.04) and in both arm curls (β = 1.67, P = 0.02) and aerobic capacity (β = 11.3, P < 0.001) among caregivers. Conclusions: Although MVPA did not increase in the RGV arm, both individuals with ADRD and caregivers demonstrated clinically meaningful gains in functional fitness, supporting the feasibility and benefit of remote dyadic PA programs. [ABSTRACT FROM AUTHOR]
Copyright of Medicine & Science in Sports & Exercise is the property of Lippincott Williams & Wilkins and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: PTOMEY L. T., B. C. HELSEL, R. N. MONTGOMERY, R. A. WASHBURN, J. R. SHERMAN, A. N. SZABO-REED, E. D. VIDONI, A. M. GORCZYCA, A. BODDE, J. G. CLINA, K. N. WILLIAMS, and J. E. DONNELLY. Effectiveness of a Remote Physical Activity Intervention in Individuals with Alzheimer&#39;s Disease and their Caregivers: Results from a Randomized Trial. Med. Sci. Sports Exerc., Vol. 58, No. 7, pp. 1388–1398, 2026. Purpose: Individuals with Alzheimer&#39;s disease and related dementias (ADRD) and their caregivers often experience reduced physical activity (PA), diminished functional fitness, and heightened health risks. Remotely delivered PA interventions may offer scalable and accessible solutions. This study compared a 6-month, group-based dyadic PA program delivered via real-time group videoconferencing (RGV) with an enhanced usual care (EUC) condition on changes in moderate-to-vigorous physical activity (MVPA) and functional fitness among dyads consisting of individuals with ADRD and their caregivers. Methods: Dyads were randomized to either the RGV or EUC arm. Both arms received wearable activity trackers and twice-monthly individualized support. The RGV group additionally participated in live, thrice-weekly group exercise sessions via videoconference. Outcomes included accelerometer-assessed MVPA and standardized measures of functional fitness. Results: Ninety-nine dyads enrolled, with 90% retention at 6 months. Mean session attendance in the RGV arm was 74% for individuals with ADRD and 69.5% for caregivers. Neither group significantly increased daily MVPA, and there were no significant between-group differences in changes in daily MVPA or sedentary time (all P &gt; 0.05). However, significant within-group improvements occurred in upper-body strength (arm curls) and aerobic capacity (2-minute step test) for both individuals with ADRD and caregivers (all P &lt; 0.05). Compared with EUC, the RGV group showed greater improvements in aerobic capacity among individuals with ADRD (β = 8.97, P = 0.04) and in both arm curls (β = 1.67, P = 0.02) and aerobic capacity (β = 11.3, P &lt; 0.001) among caregivers. Conclusions: Although MVPA did not increase in the RGV arm, both individuals with ADRD and caregivers demonstrated clinically meaningful gains in functional fitness, supporting the feasibility and benefit of remote dyadic PA programs. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Medicine &amp; Science in Sports &amp; Exercise is the property of Lippincott Williams &amp; Wilkins and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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