Bone Density in Adolescents and Young Adults with Autism Spectrum Disorders
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| Title: | Bone Density in Adolescents and Young Adults with Autism Spectrum Disorders |
|---|---|
| Language: | English |
| Authors: | Ekhlaspour, Laya, Baskaran, Charumathi, Campoverde, Karen Joanie, Sokoloff, Natalia Cano, Neumeyer, Ann M., Misra, Madhusmita |
| Source: | Journal of Autism and Developmental Disorders. Nov 2016 46(11):3387-3391. |
| Availability: | Springer. 233 Spring Street, New York, NY 10013. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-348-4505; e-mail: service-ny@springer.com; Web site: http://www.springerlink.com |
| Peer Reviewed: | Y |
| Page Count: | 5 |
| Publication Date: | 2016 |
| Document Type: | Journal Articles Reports - Research |
| Descriptors: | Autism, Pervasive Developmental Disorders, Human Body, At Risk Persons, Late Adolescents, Young Adults, Comparative Analysis, Radiology, Physiology |
| DOI: | 10.1007/s10803-016-2871-9 |
| ISSN: | 0162-3257 |
| Abstract: | Patients with autism spectrum disorder (ASD) are at increased risk for fracture, and peri-pubertal boys with ASD have lower bone mineral density (BMD) than controls. Data are lacking regarding BMD in older adolescents with ASD. We compared BMD using dual-energy X-ray absorptiometry in 9 adolescents/young adults with ASD against 9 typically developing matched controls. Patients with ASD and controls were excluded if they had other underlying conditions that may affect bone. Compared to controls, patients with ASD had (i) lower femoral neck and hip BMD Z-scores, and (ii) lower spine, femoral neck and hip height adjusted BMD Z-scores even after controlling for BMI. Understanding the underlying pathophysiology will be key to developing therapies to improve BMD and reduce fracture risk. |
| Abstractor: | As Provided |
| Number of References: | 31 |
| Entry Date: | 2016 |
| Accession Number: | EJ1117516 |
| Database: | ERIC |
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