COVID-19 in Patients with Down Syndrome: Characteristics of Hospitalisation and Disease Progression Compared to Patients without Down Syndrome
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| Title: | COVID-19 in Patients with Down Syndrome: Characteristics of Hospitalisation and Disease Progression Compared to Patients without Down Syndrome |
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| Language: | English |
| Authors: | Verena Hofmann, Dagmar Orthmann Bless |
| Source: | Journal of Intellectual & Developmental Disability. 2024 49(3):353-361. |
| Availability: | Taylor & Francis. Available from: Taylor & Francis, Ltd. 530 Walnut Street Suite 850, Philadelphia, PA 19106. Tel: 800-354-1420; Tel: 215-625-8900; Fax: 215-207-0050; Web site: http://www.tandf.co.uk/journals |
| Peer Reviewed: | Y |
| Page Count: | 9 |
| Publication Date: | 2024 |
| Document Type: | Journal Articles Reports - Research |
| Descriptors: | Foreign Countries, Down Syndrome, COVID-19, Hospitals, Patients, Mortality Rate, Age Differences, Comorbidity |
| Geographic Terms: | Switzerland |
| DOI: | 10.3109/13668250.2024.2317792 |
| ISSN: | 1366-8250 1469-9532 |
| Abstract: | Background: Individuals with Down syndrome are an at-risk population for severe COVID-19 outcomes, due to genetic predispositions and comorbidities. The current study focused on differences between persons with and without Down syndrome regarding age and severity of disease. Method: We used medical statistics to compare patients with and without Down syndrome who were admitted to Swiss hospitals (2020 and 2022) with a COVID-19 diagnosis. Differences in age, hospitalisation characteristics, mortality, and additional diagnoses were investigated. Results: Results revealed a lower median age and greater risk of intensive care unit admission and mortality among patients with Down syndrome. No differences were found in length of hospital stay. Conclusions: There is some evidence of increased vulnerability in people with Down syndrome compared to other patients, particularly in terms of mortality rates. However, compared to studies from other countries, the situation of people with Down syndrome does not appear to be particularly critical. |
| Abstractor: | As Provided |
| Entry Date: | 2024 |
| Accession Number: | EJ1435529 |
| Database: | ERIC |
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