Stimulant Treatment and Potential Adverse Outcomes in Pediatric Populations with Bipolar Disorder: A Systematic Review of the Literature
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| Title: | Stimulant Treatment and Potential Adverse Outcomes in Pediatric Populations with Bipolar Disorder: A Systematic Review of the Literature |
|---|---|
| Language: | English |
| Authors: | Hannah O'Connor (ORCID |
| Source: | Journal of Attention Disorders. 2024 28(5):740-750. |
| Availability: | SAGE Publications. 2455 Teller Road, Thousand Oaks, CA 91320. Tel: 800-818-7243; Tel: 805-499-9774; Fax: 800-583-2665; e-mail: journals@sagepub.com; Web site: https://sagepub.com |
| Peer Reviewed: | Y |
| Page Count: | 11 |
| Publication Date: | 2024 |
| Document Type: | Journal Articles Reports - Research |
| Descriptors: | Mental Disorders, Attention Deficit Hyperactivity Disorder, Comorbidity, Literature Reviews, Outcomes of Treatment, Medical Services, Children, Childrens Attitudes, Health Education |
| DOI: | 10.1177/10870547231218045 |
| ISSN: | 1087-0547 1557-1246 |
| Abstract: | Objective: To explore outcomes of stimulant treatment for ADHD in pediatric populations with particular attention to bipolar disorder (BPD). Method: We conducted a literature search of PubMed articles published prior to August 25, 2022 that focused on BPD, mania, and psychosis prior to, or as result of, stimulant treatment. We excluded studies: (1) unrelated to stimulants, (2) general stimulant research, (3) articles older than 40 years, (4) study protocols, or (5) case reports. Results: A total of 11 articles met all inclusion/exclusion criteria. Some reports found stimulant treatment safe and well-tolerated in children with comorbid BPD and ADHD. Others found evidence of treatment-emergent mania (TEM), discontinuation, and other adverse events with stimulant treatment. Conclusion: Poor outcomes associated with stimulant treatment in pediatric populations with BPD necessitate work to identify patients at risk of serious stimulant-related adverse events. Our results were limited by automated search filters and a pediatric, primarily male sample. "(J. of Att. Dis. 2024; 28(5) 740-750)" |
| Abstractor: | As Provided |
| Entry Date: | 2024 |
| Accession Number: | EJ1440944 |
| Database: | ERIC |
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