View in EDS

Hybrid Model Teaching in the Post Epidemic Period: From Nucleic Acid to Antigen for the Fluorescence Analysis of SARS-CoV-2

Saved in:
Bibliographic Details
Title: Hybrid Model Teaching in the Post Epidemic Period: From Nucleic Acid to Antigen for the Fluorescence Analysis of SARS-CoV-2
Language: English
Authors: Wenxian Zhang, Ran Liu (ORCID 0000-0002-6868-2947), Yang Shi, Hang Xing (ORCID 0000-0003-3917-8343), Jingjing Zhang (ORCID 0000-0002-1041-793X)
Source: Journal of Chemical Education. 2023 100(6):2339-2346.
Availability: Division of Chemical Education, Inc. and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: eic@jce.acs.org; Web site: http://pubs.acs.org/jchemeduc
Peer Reviewed: Y
Page Count: 8
Publication Date: 2023
Document Type: Journal Articles
Reports - Descriptive
Education Level: Higher Education
Postsecondary Education
Descriptors: Science Instruction, COVID-19, Pandemics, Science Experiments, College Science, Undergraduate Students, Chemistry, Biology, Blended Learning, Online Courses
DOI: 10.1021/acs.jchemed.2c00868
ISSN: 0021-9584
1938-1328
Abstract: Owing to the global spread of the coronavirus disease 2019 (COVID-19), education has shifted to distance online learning, whereas some face-to-face courses have been resumed with the improvement of the outbreak prevention and management situation, including a laboratory course for senior undergraduate students in chemical biology. Here, we present an innovative chemical biology experiment covering COVID-19 topics, which was created for third-year undergraduates. The basic principles of two nucleic-acid- and antigen-based diagnostic techniques for SARS-CoV-2 are demonstrated in detail. These experiments are designed to provide students with comprehensive knowledge of COVID-19 and related diagnoses in daily life. Crucially, the biosafety of this experimental manipulation was ensured by using artificial nucleic acids and recombinant protein. Furthermore, an interactive hybrid online-facing teaching model was designed to cover the key mechanism regarding PCR and serological tests of COVID-19. Finally, a satisfactory evaluation was obtained through a questionnaire, and simultaneously, reasonable improvements to the course design were suggested. The proposed curriculum provides all the necessary information for other instructors to create new courses supported by research.
Abstractor: As Provided
Entry Date: 2024
Accession Number: EJ1443039
Database: ERIC
FullText Text:
  Availability: 0
Header DbId: eric
DbLabel: ERIC
An: EJ1443039
AccessLevel: 3
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Hybrid Model Teaching in the Post Epidemic Period: From Nucleic Acid to Antigen for the Fluorescence Analysis of SARS-CoV-2
– Name: Language
  Label: Language
  Group: Lang
  Data: English
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Wenxian+Zhang%22">Wenxian Zhang</searchLink><br /><searchLink fieldCode="AR" term="%22Ran+Liu%22">Ran Liu</searchLink> (ORCID <externalLink term="https://orcid.org/0000-0002-6868-2947">0000-0002-6868-2947</externalLink>)<br /><searchLink fieldCode="AR" term="%22Yang+Shi%22">Yang Shi</searchLink><br /><searchLink fieldCode="AR" term="%22Hang+Xing%22">Hang Xing</searchLink> (ORCID <externalLink term="https://orcid.org/0000-0003-3917-8343">0000-0003-3917-8343</externalLink>)<br /><searchLink fieldCode="AR" term="%22Jingjing+Zhang%22">Jingjing Zhang</searchLink> (ORCID <externalLink term="https://orcid.org/0000-0002-1041-793X">0000-0002-1041-793X</externalLink>)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="SO" term="%22Journal+of+Chemical+Education%22"><i>Journal of Chemical Education</i></searchLink>. 2023 100(6):2339-2346.
– Name: Avail
  Label: Availability
  Group: Avail
  Data: Division of Chemical Education, Inc. and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: eic@jce.acs.org; Web site: http://pubs.acs.org/jchemeduc
– Name: PeerReviewed
  Label: Peer Reviewed
  Group: SrcInfo
  Data: Y
– Name: Pages
  Label: Page Count
  Group: Src
  Data: 8
– Name: DatePubCY
  Label: Publication Date
  Group: Date
  Data: 2023
– Name: TypeDocument
  Label: Document Type
  Group: TypDoc
  Data: Journal Articles<br />Reports - Descriptive
– Name: Audience
  Label: Education Level
  Group: Audnce
  Data: <searchLink fieldCode="EL" term="%22Higher+Education%22">Higher Education</searchLink><br /><searchLink fieldCode="EL" term="%22Postsecondary+Education%22">Postsecondary Education</searchLink>
– Name: Subject
  Label: Descriptors
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Science+Instruction%22">Science Instruction</searchLink><br /><searchLink fieldCode="DE" term="%22COVID-19%22">COVID-19</searchLink><br /><searchLink fieldCode="DE" term="%22Pandemics%22">Pandemics</searchLink><br /><searchLink fieldCode="DE" term="%22Science+Experiments%22">Science Experiments</searchLink><br /><searchLink fieldCode="DE" term="%22College+Science%22">College Science</searchLink><br /><searchLink fieldCode="DE" term="%22Undergraduate+Students%22">Undergraduate Students</searchLink><br /><searchLink fieldCode="DE" term="%22Chemistry%22">Chemistry</searchLink><br /><searchLink fieldCode="DE" term="%22Biology%22">Biology</searchLink><br /><searchLink fieldCode="DE" term="%22Blended+Learning%22">Blended Learning</searchLink><br /><searchLink fieldCode="DE" term="%22Online+Courses%22">Online Courses</searchLink>
– Name: DOI
  Label: DOI
  Group: ID
  Data: 10.1021/acs.jchemed.2c00868
– Name: ISSN
  Label: ISSN
  Group: ISSN
  Data: 0021-9584<br />1938-1328
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Owing to the global spread of the coronavirus disease 2019 (COVID-19), education has shifted to distance online learning, whereas some face-to-face courses have been resumed with the improvement of the outbreak prevention and management situation, including a laboratory course for senior undergraduate students in chemical biology. Here, we present an innovative chemical biology experiment covering COVID-19 topics, which was created for third-year undergraduates. The basic principles of two nucleic-acid- and antigen-based diagnostic techniques for SARS-CoV-2 are demonstrated in detail. These experiments are designed to provide students with comprehensive knowledge of COVID-19 and related diagnoses in daily life. Crucially, the biosafety of this experimental manipulation was ensured by using artificial nucleic acids and recombinant protein. Furthermore, an interactive hybrid online-facing teaching model was designed to cover the key mechanism regarding PCR and serological tests of COVID-19. Finally, a satisfactory evaluation was obtained through a questionnaire, and simultaneously, reasonable improvements to the course design were suggested. The proposed curriculum provides all the necessary information for other instructors to create new courses supported by research.
– Name: AbstractInfo
  Label: Abstractor
  Group: Ab
  Data: As Provided
– Name: DateEntry
  Label: Entry Date
  Group: Date
  Data: 2024
– Name: AN
  Label: Accession Number
  Group: ID
  Data: EJ1443039
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=eric&AN=EJ1443039
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1021/acs.jchemed.2c00868
    Languages:
      – Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 8
        StartPage: 2339
    Subjects:
      – SubjectFull: Science Instruction
        Type: general
      – SubjectFull: COVID-19
        Type: general
      – SubjectFull: Pandemics
        Type: general
      – SubjectFull: Science Experiments
        Type: general
      – SubjectFull: College Science
        Type: general
      – SubjectFull: Undergraduate Students
        Type: general
      – SubjectFull: Chemistry
        Type: general
      – SubjectFull: Biology
        Type: general
      – SubjectFull: Blended Learning
        Type: general
      – SubjectFull: Online Courses
        Type: general
    Titles:
      – TitleFull: Hybrid Model Teaching in the Post Epidemic Period: From Nucleic Acid to Antigen for the Fluorescence Analysis of SARS-CoV-2
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Wenxian Zhang
      – PersonEntity:
          Name:
            NameFull: Ran Liu
      – PersonEntity:
          Name:
            NameFull: Yang Shi
      – PersonEntity:
          Name:
            NameFull: Hang Xing
      – PersonEntity:
          Name:
            NameFull: Jingjing Zhang
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 06
              Type: published
              Y: 2023
          Identifiers:
            – Type: issn-print
              Value: 0021-9584
            – Type: issn-electronic
              Value: 1938-1328
          Numbering:
            – Type: volume
              Value: 100
            – Type: issue
              Value: 6
          Titles:
            – TitleFull: Journal of Chemical Education
              Type: main
ResultId 1