Creating a Course Based Undergraduate Research Experience (CURE) Genetics Yeast Laboratory Course at Xavier University of Louisiana

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Bibliographic Details
Title: Creating a Course Based Undergraduate Research Experience (CURE) Genetics Yeast Laboratory Course at Xavier University of Louisiana
Language: English
Authors: Joanna E. Haye-Bertolozzi (ORCID 0000-0001-7239-1504), Cecily B. DeFreece (ORCID 0000-0002-8243-3525), Christopher Bolden (ORCID 0000-0002-7266-9286), Kalila Daveron (ORCID 0000-0002-8529-1876), Hector Biliran (ORCID 0000-0001-5711-0532)
Source: Biochemistry and Molecular Biology Education. 2025 53(5):478-488.
Availability: Wiley. Available from: John Wiley & Sons, Inc. 111 River Street, Hoboken, NJ 07030. Tel: 800-835-6770; e-mail: cs-journals@wiley.com; Web site: https://www.wiley.com/en-us
Peer Reviewed: Y
Page Count: 11
Publication Date: 2025
Sponsoring Agency: National Institute of General Medical Sciences (NIGMS) (DHHS/NIH)
Contract Number: 5RL5GM118966
Document Type: Journal Articles
Reports - Research
Education Level: Higher Education
Postsecondary Education
Descriptors: Curriculum Development, Undergraduate Study, Undergraduate Students, Student Research, College Science, Science Education, Genetics, Laboratory Training, Scientific Research, Research Projects, Communication Skills, Research Reports, Visual Aids, Course Evaluation, Science Process Skills, Laboratory Experiments
Geographic Terms: Louisiana
DOI: 10.1002/bmb.21910
ISSN: 1470-8175
1539-3429
Abstract: Course-based undergraduate research experiences (CUREs) are important for providing undergraduates with authentic research experiences. At Xavier University of Louisiana, a Genetics Laboratory CURE course was developed and implemented. The goals of developing this Genetics CURE laboratory course were: (1) to provide a large number of students the opportunity to participate in a hypothesis-driven research project, (2) to determine the effect of different Msh6 missense variants on DNA mismatch repair (MMR), and (3) to provide opportunities to develop scientific communication skills. In the first 3 years of implementation, 595 students completed the course and participated in a project of evaluating DNA MMR utilizing the model organism, "Saccharomyces cerevisiae." Students analyzed previously uncharacterized "MSH6" alleles and summarized their findings by drafting a report in the style of a primary research article. Additionally, students communicated their findings in PowerPoint presentations, and some participated in poster presentations on campus. Examination of course evaluations indicated that students appreciated learning science theory and acquiring scientific skills in the context of a research project instead of as individual unconnected experiments.
Abstractor: As Provided
Entry Date: 2025
Accession Number: EJ1483598
Database: ERIC
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