Abnormal Developmental Trajectories in the Brain in Individuals with Reading Disability

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Bibliographic Details
Title: Abnormal Developmental Trajectories in the Brain in Individuals with Reading Disability
Language: English
Authors: Xiaohui Yan (ORCID 0000-0002-2801-3335), Shilin Xu, Guoyan Feng (ORCID 0000-0001-7086-3520), Fan Cao
Source: Developmental Science. 2026 29(1).
Availability: Wiley. Available from: John Wiley & Sons, Inc. 111 River Street, Hoboken, NJ 07030. Tel: 800-835-6770; e-mail: cs-journals@wiley.com; Web site: https://www.wiley.com/en-us
Peer Reviewed: Y
Page Count: 14
Publication Date: 2026
Document Type: Journal Articles
Reports - Research
Descriptors: Reading Difficulties, Children, Adolescents, Adults, Brain, Age Differences, Brain Hemisphere Functions, Aging (Individuals)
DOI: 10.1111/desc.70113
ISSN: 1363-755X
1467-7687
Abstract: It is unknown how the brain supports reading development in individuals with reading disability (RD). In a cross-sectional study (i.e., children, adolescents, adults), we found an age-related shift in brain activation from posterior to anterior part of the left occipitotemporal (OT) area in typical readers, supporting orthographic specialization, while RD readers did not show such a developmental shift. Furthermore, RD readers did not show age-related increase in the left superior temporal gyrus as did the typical readers, suggesting persistent phonological deficits. On the other hand, RD readers but not typical readers showed age-related increase in the left inferior frontal gyrus and the supplementary motor area. These findings suggest that the experience of RD derails the developmental trajectory of the brain. Insights gained from our study not only advance our understanding of the prognosis of RD, but also facilitate the development of age-appropriate treatment for RD.
Abstractor: As Provided
Notes: https://osf.io/8f5s9
Entry Date: 2026
Accession Number: EJ1492017
Database: ERIC
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