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Integrating CBPR and Implementation Science to Develop a PrEP-Promotion Intervention for Black Transgender Women

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Title: Integrating CBPR and Implementation Science to Develop a PrEP-Promotion Intervention for Black Transgender Women
Language: English
Authors: Scott D. Rhodes (ORCID 0000-0002-9797-8114), Lilli Mann-Jackson, Jorge Alonzo, Sandy K. Aguilar-Palma, Deborah Neffa Creech, JoAnne G. Keatley, Benjamin D. Smart, Jorge Montoya
Source: Health Education & Behavior. 2026 53(2):139-148.
Availability: SAGE Publications. 2455 Teller Road, Thousand Oaks, CA 91320. Tel: 800-818-7243; Tel: 805-499-9774; Fax: 800-583-2665; e-mail: journals@sagepub.com; Web site: https://sagepub.com
Peer Reviewed: Y
Page Count: 10
Publication Date: 2026
Sponsoring Agency: Centers for Disease Control and Prevention (CDC) (DHHS/PHS)
Document Type: Journal Articles
Reports - Research
Descriptors: African Americans, Females, Transgender People, Acquired Immunodeficiency Syndrome (AIDS), Intervention, Health Promotion, Sexually Transmitted Diseases, LGBTQ People
DOI: 10.1177/10901981251358706
ISSN: 1090-1981
1552-6127
Abstract: Black/African American transgender (trans) women experience disproportionately high rates of HIV, yet few evidence-based interventions are designed specifically for them. This study outlines the development of the "Sisters United" intervention through the adaptation of ChiCAS, an evidence-based intervention for trans Latinas. "Sisters United" promotes use of pre-exposure prophylaxis (PrEP), condoms, and medically supervised gender-affirming hormone therapy (GAHT) among Black/African American trans women. Integrating community-based participatory research and implementation science, our systematic process included multiple steps conducted in partnership with a steering committee of Black/African American trans women, other community representatives, scientists, practitioners, and consultants. We held focus groups and obtained iterative feedback about intervention objectives, messaging, and activities, including new activities focused on medical mistrust and the use of injectable PrEP, to guide the adaptation. Key intervention components developed through this process include an implementation manual, facilitator's guides for in-person and virtual delivery, video segments, and an e-learning course to support effective implementation. Like the original ChiCAS intervention, Sisters United is designed to be delivered in two sessions, with a focus on raising awareness about HIV and GAHT, building condom use skills, and overcoming barriers to health care. This intervention fills a critical gap by offering a scalable solution to promote HIV health equity among Black/African American trans women. Moreover, our systematic process can serve as a guide for others developing, refining, or adapting interventions to meet the needs of a new community or population and/or infuse updated information and innovations into an existing intervention.
Abstractor: As Provided
Entry Date: 2026
Accession Number: EJ1499427
Database: ERIC
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  Data: Integrating CBPR and Implementation Science to Develop a PrEP-Promotion Intervention for Black Transgender Women
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  Data: <searchLink fieldCode="AR" term="%22Scott+D%2E+Rhodes%22">Scott D. Rhodes</searchLink> (ORCID <externalLink term="https://orcid.org/0000-0002-9797-8114">0000-0002-9797-8114</externalLink>)<br /><searchLink fieldCode="AR" term="%22Lilli+Mann-Jackson%22">Lilli Mann-Jackson</searchLink><br /><searchLink fieldCode="AR" term="%22Jorge+Alonzo%22">Jorge Alonzo</searchLink><br /><searchLink fieldCode="AR" term="%22Sandy+K%2E+Aguilar-Palma%22">Sandy K. Aguilar-Palma</searchLink><br /><searchLink fieldCode="AR" term="%22Deborah+Neffa+Creech%22">Deborah Neffa Creech</searchLink><br /><searchLink fieldCode="AR" term="%22JoAnne+G%2E+Keatley%22">JoAnne G. Keatley</searchLink><br /><searchLink fieldCode="AR" term="%22Benjamin+D%2E+Smart%22">Benjamin D. Smart</searchLink><br /><searchLink fieldCode="AR" term="%22Jorge+Montoya%22">Jorge Montoya</searchLink>
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  Data: <searchLink fieldCode="SO" term="%22Health+Education+%26+Behavior%22"><i>Health Education & Behavior</i></searchLink>. 2026 53(2):139-148.
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  Data: SAGE Publications. 2455 Teller Road, Thousand Oaks, CA 91320. Tel: 800-818-7243; Tel: 805-499-9774; Fax: 800-583-2665; e-mail: journals@sagepub.com; Web site: https://sagepub.com
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  Data: <searchLink fieldCode="DE" term="%22African+Americans%22">African Americans</searchLink><br /><searchLink fieldCode="DE" term="%22Females%22">Females</searchLink><br /><searchLink fieldCode="DE" term="%22Transgender+People%22">Transgender People</searchLink><br /><searchLink fieldCode="DE" term="%22Acquired+Immunodeficiency+Syndrome+%28AIDS%29%22">Acquired Immunodeficiency Syndrome (AIDS)</searchLink><br /><searchLink fieldCode="DE" term="%22Intervention%22">Intervention</searchLink><br /><searchLink fieldCode="DE" term="%22Health+Promotion%22">Health Promotion</searchLink><br /><searchLink fieldCode="DE" term="%22Sexually+Transmitted+Diseases%22">Sexually Transmitted Diseases</searchLink><br /><searchLink fieldCode="DE" term="%22LGBTQ+People%22">LGBTQ People</searchLink>
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  Data: 10.1177/10901981251358706
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  Data: 1090-1981<br />1552-6127
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  Data: Black/African American transgender (trans) women experience disproportionately high rates of HIV, yet few evidence-based interventions are designed specifically for them. This study outlines the development of the "Sisters United" intervention through the adaptation of ChiCAS, an evidence-based intervention for trans Latinas. "Sisters United" promotes use of pre-exposure prophylaxis (PrEP), condoms, and medically supervised gender-affirming hormone therapy (GAHT) among Black/African American trans women. Integrating community-based participatory research and implementation science, our systematic process included multiple steps conducted in partnership with a steering committee of Black/African American trans women, other community representatives, scientists, practitioners, and consultants. We held focus groups and obtained iterative feedback about intervention objectives, messaging, and activities, including new activities focused on medical mistrust and the use of injectable PrEP, to guide the adaptation. Key intervention components developed through this process include an implementation manual, facilitator's guides for in-person and virtual delivery, video segments, and an e-learning course to support effective implementation. Like the original ChiCAS intervention, Sisters United is designed to be delivered in two sessions, with a focus on raising awareness about HIV and GAHT, building condom use skills, and overcoming barriers to health care. This intervention fills a critical gap by offering a scalable solution to promote HIV health equity among Black/African American trans women. Moreover, our systematic process can serve as a guide for others developing, refining, or adapting interventions to meet the needs of a new community or population and/or infuse updated information and innovations into an existing intervention.
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        Type: general
      – SubjectFull: Females
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      – SubjectFull: Transgender People
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