Taquicardia fetal: estudio multicéntrico retrospectivo en 9 hospitales españoles.

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Title: Taquicardia fetal: estudio multicéntrico retrospectivo en 9 hospitales españoles.
Alternate Title: Fetal tachycardia: a retrospective study in 9 Spanish centers.
Authors: Perin, F.1, Rodríguez Vázquez, M. M.1, Ferrer Menduiña, Q.2, Deiros Bronte, L.3, Rueda Núñez, F.4, Centeno Malfaz, F.5, García de la Calzada, D.6, Perich Durán, R. M.7, Zabala Argüelles, J. I.8, Galindo Izquierdo, A.9
Source: Acta Pediátrica Española. abr2015, Vol. 73 Issue 4, p88-95. 8p.
Subjects: TACHYCARDIA treatment, INFANT diseases, HOSPITALS, PROGNOSIS
Geographic Terms: SPAIN
Abstract (English): Introduction and objective: Optimal treatment for fetal tachycardia is still controversial. The aim of this study is to review the actual management and outcome of fetal tachycardia in 9 Spanish centers. Method: Retrospective multicentric study: analysis of all fetuses with tachycardia diagnosed at 9 Spanish centers between January 2008 and September 2010. Results: 37 cases were registered, 30% of which were hydropic. We had 26 no hydropic cases, of which 4 atrial flutter -all of them successfully cardioverted intrautero or after delivery- and 22 with supraventricular tachycardia (SVT), of which 17 short ventriculo-auricular (VA) interval and 5 long VA interval. Digoxin was the drug of choice in most cases. Prenatal control of the tachycardia was achieved in 93% of treated SVT with short VA interval and 50% of long VA, being digoxine effective in short VA but not long VA interval (p= 0.019). 1 fetus with supraventricular tachycardia with ventricular dysfunction died. 11 cases were hydropic, all of them diagnosed as SVT. Management strategies were highly diverse in this group. 5 patients died: 1 after delivery, 2 intrautero very shortly after starting treatment, and 2 intrautero in spite of being successfully cardioverted to sinus rhythm (1 with sotalol, 1 with flecainide). Conclusions: Hydropic fetuses have shown a high mortality rate in our population, which calls for further studies and unification of criteria. Here we propose a common protocol aimed at improving the outcome of fetal tachycardia. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Introducción y objetivo: El tratamiento óptimo de la taquicardia fetal es todavía objeto de controversia. El objetivo de este estudio es revisar el manejo y la evolución de los fetos diagnosticados de taquicardia en 9 centros españoles. Método: Se llevó a cabo un estudio multicéntrico retrospectivo, con análisis de todos los fetos con taquicardia diagnosticados en 9 centros españoles entre enero de 2008 y septiembre de 2010. Resultados: Se registraron 37 casos, un 30% hidrópicos. Un total de 26 casos no presentaba hidropesía; 4 de ellos se diagnosticaron de flutter auricular -cardioversión con éxito en todos, intraútero o posnatalmente- y 22 de taquicardia supraventricular (TSV), 17 con intervalo ventriculoauricular (VA) corto y 5 con intervalo VA largo. El fármaco inicial en la mayoría de los casos fue la digoxina. La taquicardia se controló prenatalmente en el 93% de las TSV con VA corto y en el 50% con VA largo. La digoxina resultó eficaz en los fetos con VA corto, pero ineficaz en los casos con VA largo (p= 0,019). Un feto con TSV con disfunción ventricular falleció. Asociaron hidropesía 11 casos, todos ellos diagnosticados de TSV. La estrategia terapéutica fue muy variable en este grupo. Fallecieron 5 de los fetos hidrópicos: 1 posnatalmente, 2 intraútero muy precozmente tras empezar el tratamiento, y 2 intraútero a pesar de haber convertido a ritmo sinusal con éxito (1 estando en tratamiento con flecainida y 1 con sotalol). Conclusiones: En nuestra serie se ha registrado una mortalidad muy alta de los fetos hidrópicos. Proponemos un nuevo protocolo de tratamiento concordado para mejorar la evolución de la taquicardia fetal. [ABSTRACT FROM AUTHOR]
Copyright of Acta Pediátrica Española is the property of Ediciones Mayo and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Taquicardia fetal: estudio multicéntrico retrospectivo en 9 hospitales españoles.
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  Data: Fetal tachycardia: a retrospective study in 9 Spanish centers.
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  Data: <searchLink fieldCode="AR" term="%22Perin%2C+F%2E%22">Perin, F.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Rodríguez+Vázquez%2C+M%2E+M%2E%22">Rodríguez Vázquez, M. M.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Ferrer+Menduiña%2C+Q%2E%22">Ferrer Menduiña, Q.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Deiros+Bronte%2C+L%2E%22">Deiros Bronte, L.</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Rueda+Núñez%2C+F%2E%22">Rueda Núñez, F.</searchLink><relatesTo>4</relatesTo><br /><searchLink fieldCode="AR" term="%22Centeno+Malfaz%2C+F%2E%22">Centeno Malfaz, F.</searchLink><relatesTo>5</relatesTo><br /><searchLink fieldCode="AR" term="%22García+de+la+Calzada%2C+D%2E%22">García de la Calzada, D.</searchLink><relatesTo>6</relatesTo><br /><searchLink fieldCode="AR" term="%22Perich+Durán%2C+R%2E+M%2E%22">Perich Durán, R. M.</searchLink><relatesTo>7</relatesTo><br /><searchLink fieldCode="AR" term="%22Zabala+Argüelles%2C+J%2E+I%2E%22">Zabala Argüelles, J. I.</searchLink><relatesTo>8</relatesTo><br /><searchLink fieldCode="AR" term="%22Galindo+Izquierdo%2C+A%2E%22">Galindo Izquierdo, A.</searchLink><relatesTo>9</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Acta+Pediátrica+Española%22">Acta Pediátrica Española</searchLink>. abr2015, Vol. 73 Issue 4, p88-95. 8p.
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  Data: <searchLink fieldCode="DE" term="%22TACHYCARDIA+treatment%22">TACHYCARDIA treatment</searchLink><br /><searchLink fieldCode="DE" term="%22INFANT+diseases%22">INFANT diseases</searchLink><br /><searchLink fieldCode="DE" term="%22HOSPITALS%22">HOSPITALS</searchLink><br /><searchLink fieldCode="DE" term="%22PROGNOSIS%22">PROGNOSIS</searchLink>
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  Data: Introduction and objective: Optimal treatment for fetal tachycardia is still controversial. The aim of this study is to review the actual management and outcome of fetal tachycardia in 9 Spanish centers. Method: Retrospective multicentric study: analysis of all fetuses with tachycardia diagnosed at 9 Spanish centers between January 2008 and September 2010. Results: 37 cases were registered, 30% of which were hydropic. We had 26 no hydropic cases, of which 4 atrial flutter -all of them successfully cardioverted intrautero or after delivery- and 22 with supraventricular tachycardia (SVT), of which 17 short ventriculo-auricular (VA) interval and 5 long VA interval. Digoxin was the drug of choice in most cases. Prenatal control of the tachycardia was achieved in 93% of treated SVT with short VA interval and 50% of long VA, being digoxine effective in short VA but not long VA interval (p= 0.019). 1 fetus with supraventricular tachycardia with ventricular dysfunction died. 11 cases were hydropic, all of them diagnosed as SVT. Management strategies were highly diverse in this group. 5 patients died: 1 after delivery, 2 intrautero very shortly after starting treatment, and 2 intrautero in spite of being successfully cardioverted to sinus rhythm (1 with sotalol, 1 with flecainide). Conclusions: Hydropic fetuses have shown a high mortality rate in our population, which calls for further studies and unification of criteria. Here we propose a common protocol aimed at improving the outcome of fetal tachycardia. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: Introducción y objetivo: El tratamiento óptimo de la taquicardia fetal es todavía objeto de controversia. El objetivo de este estudio es revisar el manejo y la evolución de los fetos diagnosticados de taquicardia en 9 centros españoles. Método: Se llevó a cabo un estudio multicéntrico retrospectivo, con análisis de todos los fetos con taquicardia diagnosticados en 9 centros españoles entre enero de 2008 y septiembre de 2010. Resultados: Se registraron 37 casos, un 30% hidrópicos. Un total de 26 casos no presentaba hidropesía; 4 de ellos se diagnosticaron de flutter auricular -cardioversión con éxito en todos, intraútero o posnatalmente- y 22 de taquicardia supraventricular (TSV), 17 con intervalo ventriculoauricular (VA) corto y 5 con intervalo VA largo. El fármaco inicial en la mayoría de los casos fue la digoxina. La taquicardia se controló prenatalmente en el 93% de las TSV con VA corto y en el 50% con VA largo. La digoxina resultó eficaz en los fetos con VA corto, pero ineficaz en los casos con VA largo (p= 0,019). Un feto con TSV con disfunción ventricular falleció. Asociaron hidropesía 11 casos, todos ellos diagnosticados de TSV. La estrategia terapéutica fue muy variable en este grupo. Fallecieron 5 de los fetos hidrópicos: 1 posnatalmente, 2 intraútero muy precozmente tras empezar el tratamiento, y 2 intraútero a pesar de haber convertido a ritmo sinusal con éxito (1 estando en tratamiento con flecainida y 1 con sotalol). Conclusiones: En nuestra serie se ha registrado una mortalidad muy alta de los fetos hidrópicos. Proponemos un nuevo protocolo de tratamiento concordado para mejorar la evolución de la taquicardia fetal. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Acta Pediátrica Española is the property of Ediciones Mayo and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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