Malaria grave en mujeres gestantes hospitalizadas entre 2010-2014 en el departamento de Antioquia (Colombia).
Saved in:
| Title: | Malaria grave en mujeres gestantes hospitalizadas entre 2010-2014 en el departamento de Antioquia (Colombia). |
|---|---|
| Alternate Title: | Severe malaria in pregnant women hospitalized between 2010-2014 in the Department of Antioquia (Colombia). |
| Authors: | Tobón-Castaño, Alberto1 alberto.tobon1@udea.edu.co, Edison Betancur, John1 |
| Source: | Revista Biomedica. Jun2019, Vol. 39 Issue 2, p2-38. 37p. 7 Charts, 1 Graph. |
| Abstract (English): | Introduction: Malaria during pregnancy negatively impacts maternal and neonatal health, with a high risk of clinical complications and mortality. Maternal anemia and low birth weight have been specially characterized in regions of high malarial endemicity. The clinical spectrum in low endemic areas is little known. Objective: To characterize clinically and epidemiologically the episodes of malaria during pregnancy in women hospitalized in the department of Antioquia (Colombia), 2010-2014. Materials and methods: Descriptive, cross-sectional, retrospective study, using clinical records of pregnant women with malaria caused by P. falciparum and P. vivax. The WHO diagnostic criteria for severe malaria and those from the Colombian guideline for malaria care were applied. Results: 111 cases were analyzed; 13.5% of them were classified as severe malaria according to WHO criteria; when the Colombian criteria were applied criteria the proportion of cases of severe malaria increased to 23.4%. The complications identified included hepatic dysfunction, anemia, acidosis and severe thrombocytopenia; no difference was observed in the frequency of complications by plasmodium species. Signs of danger were presented in 39.4% of the cases; pallor and jaundice were the most frequent; 40.5% showed signs of danger for pregnancy, such as persistent headache, abdominal pain and vaginal bleeding. Conclusions: Severe malaria manifests with precociously recognizable danger signs. It is a high frequency event in pregnant women, without difference by Plasmodium species. Hospital underreporting was identified in 88% of severe cases and lack of laboratory tests for a more complete diagnosis. A protocol is required for the clinical diagnosis of pregnant women with malaria. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | Introducción: La malaria durante la gestación impacta negativamente la salud materno-neonatal, con alto riesgo de complicaciones clínicas y mortalidad. En regiones de alta endemia están especialmente caracterizados la anemia materna y el bajo peso al nacer; es poco conocido el espectro clínico en zonas de baja endemia. Objetivo: Caracterizar clínica y epidemiológicamente los episodios de malaria en mujeres gestantes hospitalizadas en el departamento de Antioquia en el periodo 2010-2014. Materiales y métodos: Estudio descriptivo, transversal retrospectivo, con historias clínicas de gestantes con malaria por P. falciparum y P. vivax. Se utilizaron los criterios diagnósticos de malaria complicada de la OMS y la Guía Colombiana para Atención de la Malaria. Resultados: Se analizaron 111 casos; 13,5% clasificados como complicación grave según criterios de la OMS; con criterios de la guía colombiana la proporción asciende a 23,4%. Las complicaciones identificadas fueron disfunción hepática, anemia, acidosis y trombocitopenia grave; no se observó diferencia en la frecuencia de complicaciones por especie de plasmodio. El 39,4% de los casos presentaron signos generales de peligro, siendo palidez e ictericia los más frecuentes; 40,5% presentaron signos de peligro para la gestación, como cefalea persistente, dolor abdominal y sangrado vaginal. Conclusiones: La malaria grave es un evento de alta frecuencia en las gestantes, sin diferencia por especie de Plasmodio; se manifiesta con signos de peligro precozmente reconocibles. Se identificó subregistro hospitalario del 88% de casos de graves y falta de exámenes de laboratorio para un diagnóstico más completo. Se requiere un protocolo para el diagnóstico clínico de las gestantes con malaria. [ABSTRACT FROM AUTHOR] |
| Copyright of Revista Biomedica is the property of Centro de Investigaciones Regionales Dr. Hideyo Noguchi; Facultad de Medicina, UADY and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
Be the first to leave a comment!
