Bibliographic Details
| Title: |
Perforación intestinal espontánea contra perforación secundaria a una enterocolitis necrosante. |
| Alternate Title: |
Spontaneous intestinal perforation versus secondary perforation due to necrotizing enterocolitis. |
| Authors: |
Torres-Pinedo, Claudia Esthela1 claudia1983.cetp@gmail.com, Hoyo, Moisés Noe Gerardo-del2, Fernández-Valiñas, Samuel3, Rendón-Macías, Mario Enrique4 |
| Source: |
Revista Mexicana de Pediatria. ene/feb2024, Vol. 91 Issue 1, p12-16. 5p. |
| Subjects: |
LOW birth weight, INTESTINAL perforation, DISEASE progression, NEWBORN infants, SYMPTOMS |
| Abstract (English): |
Introduction: intestinal perforation in premature or low birth weight neonates can occur spontaneously (SIP) or secondary to necrotizing enterocolitis (NEC); distinguish between these two etiologies based on clinical presentation is challenging. Objective: to compare the medical history, clinical characteristics, progression, and treatment outcomes between neonates with SIP and NEC. Material and methods: a cross-sectional comparative study was conducted on the clinical, surgical, and histopathological characteristics of five neonates with SIP and seven with stage IIIB NEC. Results: the clinical history and progression were similar among all patients, except for fewer gestational weeks at birth in neonates with SIP (27 weeks vs 30 weeks). Histopathological analysis revealed more extensive areas of acute inflammation and necrosis in NEC, with a higher rate of complications compared to SIP (71.4% vs 40%). Conclusions: the clinical presentations of neonates with SIP and NEC are very similar, and diagnosis is typically made through surgical and histopathological findings. Prognosis was less favorable in patients with NEC. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): |
Introducción: la perforación intestinal en el neonato prematuro o de bajo peso puede ser causada de forma espontánea (PIE) o secundaria a enterocolitis necrosante (ECN), su distinción clínica suele ser difícil. Objetivo: comparar los antecedentes, características clínicas, evolución y tratamiento entre pacientes con PIE y ECN. Material y métodos: se realizó un estudio transversal comparativo de las características clínicas, quirúrgicas e histopatológicas entre cinco neonatos con PIE y siete con ECN estadio IIIB. Resultados: los antecedentes y evolución clínica en todos los pacientes fueron semejantes con excepción de menos semanas de gestación (SDG) al nacimiento en los neonatos con PIE (27 SDG vs 30 SDG). Por otro lado, el reporte histopatológico mostró datos de inflamación aguda con áreas de necrosis más extensa en la ECN. En este grupo hubo una mayor proporción de complicaciones, en comparación de pacientes con PIE (71.4 vs 40%). Conclusiones: la presentación clínica en los pacientes con PIE y ECN es muy semejante y el diagnóstico suele ser quirúrgico e histopatológico. El pronóstico fue menos favorable en pacientes con ECN. [ABSTRACT FROM AUTHOR] |
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| Database: |
MedicLatina |