Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27).

Saved in:
Bibliographic Details
Title: Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27).
Authors: McCabe MT; Cancer Epigenetics Discovery Performance Unit, Cancer Research, Oncology Research and Development, GlaxoSmithKline, Collegeville, PA 19426, USA. michael.t.mccabe@gsk.com, Graves AP, Ganji G, Diaz E, Halsey WS, Jiang Y, Smitheman KN, Ott HM, Pappalardi MB, Allen KE, Chen SB, Della Pietra A 3rd, Dul E, Hughes AM, Gilbert SA, Thrall SH, Tummino PJ, Kruger RG, Brandt M, Schwartz B, Creasy CL
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2012 Feb 21; Vol. 109 (8), pp. 2989-94. Date of Electronic Publication: 2012 Feb 08.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 22323599
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27).
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22McCabe+MT%22">McCabe MT</searchLink>; Cancer Epigenetics Discovery Performance Unit, Cancer Research, Oncology Research and Development, GlaxoSmithKline, Collegeville, PA 19426, USA. michael.t.mccabe@gsk.com<br /><searchLink fieldCode="AU" term="%22Graves+AP%22">Graves AP</searchLink><br /><searchLink fieldCode="AU" term="%22Ganji+G%22">Ganji G</searchLink><br /><searchLink fieldCode="AU" term="%22Diaz+E%22">Diaz E</searchLink><br /><searchLink fieldCode="AU" term="%22Halsey+WS%22">Halsey WS</searchLink><br /><searchLink fieldCode="AU" term="%22Jiang+Y%22">Jiang Y</searchLink><br /><searchLink fieldCode="AU" term="%22Smitheman+KN%22">Smitheman KN</searchLink><br /><searchLink fieldCode="AU" term="%22Ott+HM%22">Ott HM</searchLink><br /><searchLink fieldCode="AU" term="%22Pappalardi+MB%22">Pappalardi MB</searchLink><br /><searchLink fieldCode="AU" term="%22Allen+KE%22">Allen KE</searchLink><br /><searchLink fieldCode="AU" term="%22Chen+SB%22">Chen SB</searchLink><br /><searchLink fieldCode="AU" term="%22Della+Pietra+A+3rd%22">Della Pietra A 3rd</searchLink><br /><searchLink fieldCode="AU" term="%22Dul+E%22">Dul E</searchLink><br /><searchLink fieldCode="AU" term="%22Hughes+AM%22">Hughes AM</searchLink><br /><searchLink fieldCode="AU" term="%22Gilbert+SA%22">Gilbert SA</searchLink><br /><searchLink fieldCode="AU" term="%22Thrall+SH%22">Thrall SH</searchLink><br /><searchLink fieldCode="AU" term="%22Tummino+PJ%22">Tummino PJ</searchLink><br /><searchLink fieldCode="AU" term="%22Kruger+RG%22">Kruger RG</searchLink><br /><searchLink fieldCode="AU" term="%22Brandt+M%22">Brandt M</searchLink><br /><searchLink fieldCode="AU" term="%22Schwartz+B%22">Schwartz B</searchLink><br /><searchLink fieldCode="AU" term="%22Creasy+CL%22">Creasy CL</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2012 Feb 21; Vol. 109 (8), pp. 2989-94. <i>Date of Electronic Publication: </i>2012 Feb 08.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22National+Academy+of+Sciences%22">National Academy of Sciences </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7505876 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1091-6490 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200278424%22">00278424 </searchLink><i>NLM ISO Abbreviation: </i>Proc Natl Acad Sci U S A <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=22323599
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1073/pnas.1116418109
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 2989
    Titles:
      – TitleFull: Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27).
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: McCabe MT
      – PersonEntity:
          Name:
            NameFull: Graves AP
      – PersonEntity:
          Name:
            NameFull: Ganji G
      – PersonEntity:
          Name:
            NameFull: Diaz E
      – PersonEntity:
          Name:
            NameFull: Halsey WS
      – PersonEntity:
          Name:
            NameFull: Jiang Y
      – PersonEntity:
          Name:
            NameFull: Smitheman KN
      – PersonEntity:
          Name:
            NameFull: Ott HM
      – PersonEntity:
          Name:
            NameFull: Pappalardi MB
      – PersonEntity:
          Name:
            NameFull: Allen KE
      – PersonEntity:
          Name:
            NameFull: Chen SB
      – PersonEntity:
          Name:
            NameFull: Della Pietra A 3rd
      – PersonEntity:
          Name:
            NameFull: Dul E
      – PersonEntity:
          Name:
            NameFull: Hughes AM
      – PersonEntity:
          Name:
            NameFull: Gilbert SA
      – PersonEntity:
          Name:
            NameFull: Thrall SH
      – PersonEntity:
          Name:
            NameFull: Tummino PJ
      – PersonEntity:
          Name:
            NameFull: Kruger RG
      – PersonEntity:
          Name:
            NameFull: Brandt M
      – PersonEntity:
          Name:
            NameFull: Schwartz B
      – PersonEntity:
          Name:
            NameFull: Creasy CL
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 21
              M: 02
              Text: 2012 Feb 21
              Type: published
              Y: 2012
          Identifiers:
            – Type: issn-electronic
              Value: 1091-6490
          Numbering:
            – Type: volume
              Value: 109
            – Type: issue
              Value: 8
          Titles:
            – TitleFull: Proceedings of the National Academy of Sciences of the United States of America
              Type: main
ResultId 1