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Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy.

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Title: Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy.
Authors: Frankowski KJ; University of Kansas Specialized Chemistry Center, University of Kansas, Lawrence, KS 66047., Hedrick MP, Gosalia P, Li K, Shi S, Whipple D, Ghosh P, Prisinzano TE, Schoenen FJ, Su Y, Vasile S, Sergienko E, Gray W, Hariharan S, Milan L, Heynen-Genel S, Mangravita-Novo A, Vicchiarelli M, Smith LH, Streicher JM, Caron MG, Barak LS, Bohn LM, Chung TD, Aubé J
Source: ACS chemical neuroscience [ACS Chem Neurosci] 2012 Mar 21; Vol. 3 (3), pp. 221-236. Date of Electronic Publication: 2012 Jan 20.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="JN" term="%22101525337%22">ACS chemical neuroscience</searchLink> [ACS Chem Neurosci] 2012 Mar 21; Vol. 3 (3), pp. 221-236. <i>Date of Electronic Publication: </i>2012 Jan 20.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101525337 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1948-7193 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219487193%22">19487193 </searchLink><i>NLM ISO Abbreviation: </i>ACS Chem Neurosci <i>Subsets: </i>PubMed not MEDLINE
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