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Design and anticipated outcomes of the eMERGE-PGx project: a multicenter pilot for preemptive pharmacogenomics in electronic health record systems.

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Title: Design and anticipated outcomes of the eMERGE-PGx project: a multicenter pilot for preemptive pharmacogenomics in electronic health record systems.
Authors: Rasmussen-Torvik LJ; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Stallings SC; Vanderbilt Institute for Clinical and Translational Research, Nashville, Tennessee, USA., Gordon AS; Department of Genome Sciences, University of Washington, Seattle, Washington, USA., Almoguera B; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Basford MA; Vanderbilt Institute for Clinical and Translational Research, Nashville, Tennessee, USA., Bielinski SJ; Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA., Brautbar A; Center for Human Genetics, Marshfield Clinic Research Foundation, Marshfield, Wisconsin, USA., Brilliant MH; Center for Human Genetics, Marshfield Clinic Research Foundation, Marshfield, Wisconsin, USA., Carrell DS; Group Health Research Institute, Seattle, Washington, USA., Connolly JJ; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Crosslin DR; Department of Genome Sciences, University of Washington, Seattle, Washington, USA., Doheny KF; Center for Inherited Disease Research, Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Gallego CJ; Division of Medical Genetics, University of Washington, Seattle, Washington, USA., Gottesman O; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Kim DS; Department of Genome Sciences, University of Washington, Seattle, Washington, USA., Leppig KA; Group Health Research Institute, Seattle, Washington, USA., Li R; Division of Genomic Medicine, National Human Genome Research Institute, Bethesda, Maryland, USA., Lin S; Biomedical Informatics Research Center, Marshfield Clinic Research Foundation, Marshfield, Wisconsin, USA., Manzi S; Division of Genetics and Genomics, Boston Children's Hospital, Boston, Massachusetts, USA., Mejia AR; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Pacheco JA; Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Pan V; Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Pathak J; Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA., Perry CL; Division of Genetics and Genomics, Boston Children's Hospital, Boston, Massachusetts, USA., Peterson JF; Department of Biomedical Informatics and Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Prows CA; 1] Division Human Genetics, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA [2] Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Ralston J; Group Health Research Institute, Seattle, Washington, USA., Rasmussen LV; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Ritchie MD; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, State College, Pennsylvania, USA., Sadhasivam S; 1] Department of Anesthesia, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA [2] Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA., Scott SA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Smith M; Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Vega A; Mount Sinai Faculty Practice Associates Primary Care Program, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Vinks AA; 1] Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA [2] Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Volpi S; Division of Genomic Medicine, National Human Genome Research Institute, Bethesda, Maryland, USA., Wolf WA; 1] Division of Genetics and Genomics, Boston Children's Hospital, Boston, Massachusetts, USA [2] Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA., Bottinger E; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Chisholm RL; Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Chute CG; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA., Haines JL; Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Harley JB; 1] Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA [2] Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, USA [3] US Department of Veterans Affairs Medical Center, Cincinnati, Ohio, USA., Keating B; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Holm IA; 1] Division of Genetics and Genomics, Boston Children's Hospital, Boston, Massachusetts, USA [2] Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA [3] The Manton Center for Orphan Disease Research, Boston Children's Hospital, Boston, Massachusetts, USA., Kullo IJ; Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA., Jarvik GP; Division of Medical Genetics, University of Washington, Seattle, Washington, USA., Larson EB; Group Health Research Institute, Seattle, Washington, USA., Manolio T; Division of Genomic Medicine, National Human Genome Research Institute, Bethesda, Maryland, USA., McCarty CA; Essentia Institute of Rural Health, Duluth, Minnesota, USA., Nickerson DA; Department of Genome Sciences, University of Washington, Seattle, Washington, USA., Scherer SE; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA., Williams MS; Genomic Medicine Institute, Geisinger Health System, Danville, Pennsylvania, USA., Roden DM; 1] Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA [2] Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Denny JC; 1] Department of Biomedical Informatics and Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA [2] Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2014 Oct; Vol. 96 (4), pp. 482-9. Date of Electronic Publication: 2014 Jun 24.
Publication Type: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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