Optimizing human apyrase to treat arterial thrombosis and limit reperfusion injury without increasing bleeding risk.
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| Title: | Optimizing human apyrase to treat arterial thrombosis and limit reperfusion injury without increasing bleeding risk. |
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| Authors: | Moeckel D; Center for Cardiovascular Research, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA., Jeong SS; APT Therapeutics Inc., 4041 Forest Park Avenue, St. Louis, MO 63108, USA., Sun X; Division of Gastroenterology/Hepatology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA., Broekman MJ; Thrombosis Research Laboratory, Research Service, Veterans Affairs New York Harbor Healthcare System, New York, NY 10010, USA. Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY 10021, USA., Nguyen A; Center for Cardiovascular Research, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA., Drosopoulos JH; Thrombosis Research Laboratory, Research Service, Veterans Affairs New York Harbor Healthcare System, New York, NY 10010, USA. Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY 10021, USA., Marcus AJ; Thrombosis Research Laboratory, Research Service, Veterans Affairs New York Harbor Healthcare System, New York, NY 10010, USA. Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY 10021, USA., Robson SC; Division of Gastroenterology/Hepatology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA., Chen R; APT Therapeutics Inc., 4041 Forest Park Avenue, St. Louis, MO 63108, USA. rchen@apt-therapeutics.com dabendsc@DOM.wustl.edu., Abendschein D; Center for Cardiovascular Research, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA. rchen@apt-therapeutics.com dabendsc@DOM.wustl.edu. |
| Source: | Science translational medicine [Sci Transl Med] 2014 Aug 06; Vol. 6 (248), pp. 248ra105. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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