Dual-specificity phosphatase 5 regulates nuclear ERK activity and suppresses skin cancer by inhibiting mutant Harvey-Ras (HRasQ61L)-driven SerpinB2 expression.

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Title: Dual-specificity phosphatase 5 regulates nuclear ERK activity and suppresses skin cancer by inhibiting mutant Harvey-Ras (HRasQ61L)-driven SerpinB2 expression.
Authors: Rushworth LK; Cancer Research-UK Stress Response Laboratory, Division of Cancer Research, Medical Research Institute, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom;, Kidger AM; Cancer Research-UK Stress Response Laboratory, Division of Cancer Research, Medical Research Institute, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom;, Delavaine L; Cancer Research-UK Stress Response Laboratory, Division of Cancer Research, Medical Research Institute, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom;, Stewart G; Cancer Research-UK Stress Response Laboratory, Division of Cancer Research, Medical Research Institute, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom;, van Schelven S; Cancer Research-UK Stress Response Laboratory, Division of Cancer Research, Medical Research Institute, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom;, Davidson J; Cancer Research-UK Stress Response Laboratory, Division of Cancer Research, Medical Research Institute, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom;, Bryant CJ; Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom; and., Caddye E; Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom; and., East P; Bioinformatics and Biostatistics Group, Cancer Research-UK London Research Institute, London WC2A 3LY, United Kingdom., Caunt CJ; Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom; and., Keyse SM; Cancer Research-UK Stress Response Laboratory, Division of Cancer Research, Medical Research Institute, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom; s.m.keyse@dundee.ac.uk.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2014 Dec 23; Vol. 111 (51), pp. 18267-72. Date of Electronic Publication: 2014 Dec 08.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dual-specificity phosphatase 5 regulates nuclear ERK activity and suppresses skin cancer by inhibiting mutant Harvey-Ras (HRasQ61L)-driven SerpinB2 expression.
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  Data: <searchLink fieldCode="AU" term="%22Rushworth+LK%22">Rushworth LK</searchLink>; Cancer Research-UK Stress Response Laboratory, Division of Cancer Research, Medical Research Institute, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom;<br /><searchLink fieldCode="AU" term="%22Kidger+AM%22">Kidger AM</searchLink>; Cancer Research-UK Stress Response Laboratory, Division of Cancer Research, Medical Research Institute, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom;<br /><searchLink fieldCode="AU" term="%22Delavaine+L%22">Delavaine L</searchLink>; Cancer Research-UK Stress Response Laboratory, Division of Cancer Research, Medical Research Institute, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom;<br /><searchLink fieldCode="AU" term="%22Stewart+G%22">Stewart G</searchLink>; Cancer Research-UK Stress Response Laboratory, Division of Cancer Research, Medical Research Institute, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom;<br /><searchLink fieldCode="AU" term="%22van+Schelven+S%22">van Schelven S</searchLink>; Cancer Research-UK Stress Response Laboratory, Division of Cancer Research, Medical Research Institute, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom;<br /><searchLink fieldCode="AU" term="%22Davidson+J%22">Davidson J</searchLink>; Cancer Research-UK Stress Response Laboratory, Division of Cancer Research, Medical Research Institute, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom;<br /><searchLink fieldCode="AU" term="%22Bryant+CJ%22">Bryant CJ</searchLink>; Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom; and.<br /><searchLink fieldCode="AU" term="%22Caddye+E%22">Caddye E</searchLink>; Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom; and.<br /><searchLink fieldCode="AU" term="%22East+P%22">East P</searchLink>; Bioinformatics and Biostatistics Group, Cancer Research-UK London Research Institute, London WC2A 3LY, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Caunt+CJ%22">Caunt CJ</searchLink>; Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom; and.<br /><searchLink fieldCode="AU" term="%22Keyse+SM%22">Keyse SM</searchLink>; Cancer Research-UK Stress Response Laboratory, Division of Cancer Research, Medical Research Institute, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom; s.m.keyse@dundee.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2014 Dec 23; Vol. 111 (51), pp. 18267-72. <i>Date of Electronic Publication: </i>2014 Dec 08.
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