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Identification of metabolically stable 5'-phosphate analogs that support single-stranded siRNA activity.

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Title: Identification of metabolically stable 5'-phosphate analogs that support single-stranded siRNA activity.
Authors: Prakash TP; Isis Pharmaceuticals Inc., 2855 Gazelle Ct, Carlsbad, CA 92010, USA tprakash@isisph.com., Lima WF; Isis Pharmaceuticals Inc., 2855 Gazelle Ct, Carlsbad, CA 92010, USA., Murray HM; Isis Pharmaceuticals Inc., 2855 Gazelle Ct, Carlsbad, CA 92010, USA., Li W; Isis Pharmaceuticals Inc., 2855 Gazelle Ct, Carlsbad, CA 92010, USA., Kinberger GA; Isis Pharmaceuticals Inc., 2855 Gazelle Ct, Carlsbad, CA 92010, USA., Chappell AE; Isis Pharmaceuticals Inc., 2855 Gazelle Ct, Carlsbad, CA 92010, USA., Gaus H; Isis Pharmaceuticals Inc., 2855 Gazelle Ct, Carlsbad, CA 92010, USA., Seth PP; Isis Pharmaceuticals Inc., 2855 Gazelle Ct, Carlsbad, CA 92010, USA., Bhat B; Isis Pharmaceuticals Inc., 2855 Gazelle Ct, Carlsbad, CA 92010, USA., Crooke ST; Isis Pharmaceuticals Inc., 2855 Gazelle Ct, Carlsbad, CA 92010, USA., Swayze EE; Isis Pharmaceuticals Inc., 2855 Gazelle Ct, Carlsbad, CA 92010, USA.
Source: Nucleic acids research [Nucleic Acids Res] 2015 Mar 31; Vol. 43 (6), pp. 2993-3011. Date of Electronic Publication: 2015 Mar 09.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Identification of metabolically stable 5'-phosphate analogs that support single-stranded siRNA activity.
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  Data: <searchLink fieldCode="AU" term="%22Prakash+TP%22">Prakash TP</searchLink>; Isis Pharmaceuticals Inc., 2855 Gazelle Ct, Carlsbad, CA 92010, USA tprakash@isisph.com.<br /><searchLink fieldCode="AU" term="%22Lima+WF%22">Lima WF</searchLink>; Isis Pharmaceuticals Inc., 2855 Gazelle Ct, Carlsbad, CA 92010, USA.<br /><searchLink fieldCode="AU" term="%22Murray+HM%22">Murray HM</searchLink>; Isis Pharmaceuticals Inc., 2855 Gazelle Ct, Carlsbad, CA 92010, USA.<br /><searchLink fieldCode="AU" term="%22Li+W%22">Li W</searchLink>; Isis Pharmaceuticals Inc., 2855 Gazelle Ct, Carlsbad, CA 92010, USA.<br /><searchLink fieldCode="AU" term="%22Kinberger+GA%22">Kinberger GA</searchLink>; Isis Pharmaceuticals Inc., 2855 Gazelle Ct, Carlsbad, CA 92010, USA.<br /><searchLink fieldCode="AU" term="%22Chappell+AE%22">Chappell AE</searchLink>; Isis Pharmaceuticals Inc., 2855 Gazelle Ct, Carlsbad, CA 92010, USA.<br /><searchLink fieldCode="AU" term="%22Gaus+H%22">Gaus H</searchLink>; Isis Pharmaceuticals Inc., 2855 Gazelle Ct, Carlsbad, CA 92010, USA.<br /><searchLink fieldCode="AU" term="%22Seth+PP%22">Seth PP</searchLink>; Isis Pharmaceuticals Inc., 2855 Gazelle Ct, Carlsbad, CA 92010, USA.<br /><searchLink fieldCode="AU" term="%22Bhat+B%22">Bhat B</searchLink>; Isis Pharmaceuticals Inc., 2855 Gazelle Ct, Carlsbad, CA 92010, USA.<br /><searchLink fieldCode="AU" term="%22Crooke+ST%22">Crooke ST</searchLink>; Isis Pharmaceuticals Inc., 2855 Gazelle Ct, Carlsbad, CA 92010, USA.<br /><searchLink fieldCode="AU" term="%22Swayze+EE%22">Swayze EE</searchLink>; Isis Pharmaceuticals Inc., 2855 Gazelle Ct, Carlsbad, CA 92010, USA.
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