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Autologous Hematopoetic Stem Cell Transplantation for Refractory Crohn Disease: A Randomized Clinical Trial.

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Title: Autologous Hematopoetic Stem Cell Transplantation for Refractory Crohn Disease: A Randomized Clinical Trial.
Authors: Hawkey CJ; Nottingham Digestive Diseases Centre, School of Clinical Sciences, Queens Medical Centre, Nottingham, United Kingdom., Allez M; APHP, Hôpital Saint Louis, Department of Gastroenterology, INSERM UMRS 1160, Paris Diderot, Sorbonne Paris-Cité University, Paris, France., Clark MM; Nottingham Digestive Diseases Centre, School of Clinical Sciences, Queens Medical Centre, Nottingham, United Kingdom., Labopin M; European Group for Blood and Marrow Transplantation, Paris, France., Lindsay JO; Centre for Immunobiology, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom., Ricart E; Gastroenterology Department, Hospital Clinic, CIBER-EHD, Barcelona, Spain., Rogler G; Division of Gastroenterology and Hepatology, University Hospital, University of Zurich, Zurich, Switzerland., Rovira M; Hematology Department, Hospital Clinic, Barcelona, Spain., Satsangi J; Gastro-intestinal Unit, Institute of Genetics and Molecular Medicine, Western General Hospital University of Edinburgh, Edinburgh, United Kingdom., Danese S; IBD Center, Humanitas Research Hospital, Rozzano, Milan, Italy., Russell N; Haematology School of Medicine, University of Nottingham, Nottingham City Hospital, Nottingham, United Kingdom., Gribben J; Centre for Haemato-Oncology, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom., Johnson P; Department of Haematology, Western General Hospital, Edinburgh, United Kingdom., Larghero J; Biotherapies and Cell Therapy Unit, AP-HP Hôpital Saint-Louis, Paris 7 University, France., Thieblemont C; Haematology/Transplantation, AP-HP Hôpital Saint-Louis, Paris 7 University, Paris, France., Ardizzone S; IBD Unit, Department of Gastroenterology, 'L. Sacco' University Hospital, Milan, Italy., Dierickx D; Department of Hematology, University hospitals Leuven, Gasthuisberg, Belgium University Hospital, Belgium., Ibatici A; Divisione Ematologia e Trapianto di Midollo, IRCCS San Martino-IST, Genova, Italy., Littlewood T; Department of Haematology, Oxford University Hospitals NHS Trust, Oxford, United Kingdom., Onida F; Hematology-BMT Center, Fondazione IRCCS Ospedale Maggiore Policlinico, University of Milan, Milan, Italy., Schanz U; Division of Hematology, University Hospital Zurich, Zurich, Switzerland., Vermeire S; Department of Gastroenterology University Hospital Gasthuisberg Herestraat, Leuven, Belgium., Colombel JF; Department of Hepato-Gastroenterology, Hopital Huriez, Lille, France23Department of Gastroenterology, Icahn School of Medicine, New York, New York., Jouet JP; Departement of Hematology, Hôpital Claude-Huriez, Lille, France., Clark E; EBMT Clinical Trials, European Group for Blood and Marrow Transplantation, London, United Kingdom., Saccardi R; European Blood & Marrow Transplantation Group, Hematology Department, Careggi University Hospital, Florence, Italy., Tyndall A; Department of Rheumatology, University Hospital, Basel, Switzerland., Travis S; Translational Gastroenterology Unit, Oxford University Hospital, Oxford, United Kingdom., Farge D; Internal Medicine and Vascular Disease Unit AP-HP Hôpital Saint-Louis, Paris 7 University, France.
Source: JAMA [JAMA] 2015 Dec 15; Vol. 314 (23), pp. 2524-34.
Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE
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  Data: Autologous Hematopoetic Stem Cell Transplantation for Refractory Crohn Disease: A Randomized Clinical Trial.
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  Data: <searchLink fieldCode="AU" term="%22Hawkey+CJ%22">Hawkey CJ</searchLink>; Nottingham Digestive Diseases Centre, School of Clinical Sciences, Queens Medical Centre, Nottingham, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Allez+M%22">Allez M</searchLink>; APHP, Hôpital Saint Louis, Department of Gastroenterology, INSERM UMRS 1160, Paris Diderot, Sorbonne Paris-Cité University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Clark+MM%22">Clark MM</searchLink>; Nottingham Digestive Diseases Centre, School of Clinical Sciences, Queens Medical Centre, Nottingham, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Labopin+M%22">Labopin M</searchLink>; European Group for Blood and Marrow Transplantation, Paris, France.<br /><searchLink fieldCode="AU" term="%22Lindsay+JO%22">Lindsay JO</searchLink>; Centre for Immunobiology, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Ricart+E%22">Ricart E</searchLink>; Gastroenterology Department, Hospital Clinic, CIBER-EHD, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Rogler+G%22">Rogler G</searchLink>; Division of Gastroenterology and Hepatology, University Hospital, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Rovira+M%22">Rovira M</searchLink>; Hematology Department, Hospital Clinic, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Satsangi+J%22">Satsangi J</searchLink>; Gastro-intestinal Unit, Institute of Genetics and Molecular Medicine, Western General Hospital University of Edinburgh, Edinburgh, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Danese+S%22">Danese S</searchLink>; IBD Center, Humanitas Research Hospital, Rozzano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Russell+N%22">Russell N</searchLink>; Haematology School of Medicine, University of Nottingham, Nottingham City Hospital, Nottingham, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gribben+J%22">Gribben J</searchLink>; Centre for Haemato-Oncology, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Johnson+P%22">Johnson P</searchLink>; Department of Haematology, Western General Hospital, Edinburgh, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Larghero+J%22">Larghero J</searchLink>; Biotherapies and Cell Therapy Unit, AP-HP Hôpital Saint-Louis, Paris 7 University, France.<br /><searchLink fieldCode="AU" term="%22Thieblemont+C%22">Thieblemont C</searchLink>; Haematology/Transplantation, AP-HP Hôpital Saint-Louis, Paris 7 University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Ardizzone+S%22">Ardizzone S</searchLink>; IBD Unit, Department of Gastroenterology, 'L. Sacco' University Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Dierickx+D%22">Dierickx D</searchLink>; Department of Hematology, University hospitals Leuven, Gasthuisberg, Belgium University Hospital, Belgium.<br /><searchLink fieldCode="AU" term="%22Ibatici+A%22">Ibatici A</searchLink>; Divisione Ematologia e Trapianto di Midollo, IRCCS San Martino-IST, Genova, Italy.<br /><searchLink fieldCode="AU" term="%22Littlewood+T%22">Littlewood T</searchLink>; Department of Haematology, Oxford University Hospitals NHS Trust, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Onida+F%22">Onida F</searchLink>; Hematology-BMT Center, Fondazione IRCCS Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Schanz+U%22">Schanz U</searchLink>; Division of Hematology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Vermeire+S%22">Vermeire S</searchLink>; Department of Gastroenterology University Hospital Gasthuisberg Herestraat, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Colombel+JF%22">Colombel JF</searchLink>; Department of Hepato-Gastroenterology, Hopital Huriez, Lille, France23Department of Gastroenterology, Icahn School of Medicine, New York, New York.<br /><searchLink fieldCode="AU" term="%22Jouet+JP%22">Jouet JP</searchLink>; Departement of Hematology, Hôpital Claude-Huriez, Lille, France.<br /><searchLink fieldCode="AU" term="%22Clark+E%22">Clark E</searchLink>; EBMT Clinical Trials, European Group for Blood and Marrow Transplantation, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Saccardi+R%22">Saccardi R</searchLink>; European Blood & Marrow Transplantation Group, Hematology Department, Careggi University Hospital, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Tyndall+A%22">Tyndall A</searchLink>; Department of Rheumatology, University Hospital, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Travis+S%22">Travis S</searchLink>; Translational Gastroenterology Unit, Oxford University Hospital, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Farge+D%22">Farge D</searchLink>; Internal Medicine and Vascular Disease Unit AP-HP Hôpital Saint-Louis, Paris 7 University, France.
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