Discovery of Potent and Selective Inhibitors of Phosphodiesterase 1 for the Treatment of Cognitive Impairment Associated with Neurodegenerative and Neuropsychiatric Diseases.
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| Title: | Discovery of Potent and Selective Inhibitors of Phosphodiesterase 1 for the Treatment of Cognitive Impairment Associated with Neurodegenerative and Neuropsychiatric Diseases. |
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| Authors: | Li P; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States., Zheng H; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States., Zhao J; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States., Zhang L; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States., Yao W; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States., Zhu H; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States., Beard JD; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States., Ida K; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd. , 26-1, Muraoka-Higashi 2-Chome, Fujisawa, Kanagawa 251-8555, Japan., Lane W; Department of Structural Biology, Takeda California, Inc. , 10410 Science Center Drive, San Diego, California 92121, United States., Snell G; Department of Structural Biology, Takeda California, Inc. , 10410 Science Center Drive, San Diego, California 92121, United States., Sogabe S; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd. , 26-1, Muraoka-Higashi 2-Chome, Fujisawa, Kanagawa 251-8555, Japan., Heyser CJ; Department of Neurosciences, University of California, San Diego , 9500 Gilman Drive, #0608, La Jolla, California 92093, United States., Snyder GL; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States., Hendrick JP; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States., Vanover KE; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States., Davis RE; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States., Wennogle LP; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States. |
| Source: | Journal of medicinal chemistry [J Med Chem] 2016 Feb 11; Vol. 59 (3), pp. 1149-64. Date of Electronic Publication: 2016 Feb 02. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 26789933 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Discovery of Potent and Selective Inhibitors of Phosphodiesterase 1 for the Treatment of Cognitive Impairment Associated with Neurodegenerative and Neuropsychiatric Diseases. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Li+P%22">Li P</searchLink>; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States.<br /><searchLink fieldCode="AU" term="%22Zheng+H%22">Zheng H</searchLink>; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States.<br /><searchLink fieldCode="AU" term="%22Zhao+J%22">Zhao J</searchLink>; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States.<br /><searchLink fieldCode="AU" term="%22Yao+W%22">Yao W</searchLink>; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States.<br /><searchLink fieldCode="AU" term="%22Zhu+H%22">Zhu H</searchLink>; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States.<br /><searchLink fieldCode="AU" term="%22Beard+JD%22">Beard JD</searchLink>; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States.<br /><searchLink fieldCode="AU" term="%22Ida+K%22">Ida K</searchLink>; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd. , 26-1, Muraoka-Higashi 2-Chome, Fujisawa, Kanagawa 251-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Lane+W%22">Lane W</searchLink>; Department of Structural Biology, Takeda California, Inc. , 10410 Science Center Drive, San Diego, California 92121, United States.<br /><searchLink fieldCode="AU" term="%22Snell+G%22">Snell G</searchLink>; Department of Structural Biology, Takeda California, Inc. , 10410 Science Center Drive, San Diego, California 92121, United States.<br /><searchLink fieldCode="AU" term="%22Sogabe+S%22">Sogabe S</searchLink>; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd. , 26-1, Muraoka-Higashi 2-Chome, Fujisawa, Kanagawa 251-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Heyser+CJ%22">Heyser CJ</searchLink>; Department of Neurosciences, University of California, San Diego , 9500 Gilman Drive, #0608, La Jolla, California 92093, United States.<br /><searchLink fieldCode="AU" term="%22Snyder+GL%22">Snyder GL</searchLink>; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States.<br /><searchLink fieldCode="AU" term="%22Hendrick+JP%22">Hendrick JP</searchLink>; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States.<br /><searchLink fieldCode="AU" term="%22Vanover+KE%22">Vanover KE</searchLink>; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States.<br /><searchLink fieldCode="AU" term="%22Davis+RE%22">Davis RE</searchLink>; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States.<br /><searchLink fieldCode="AU" term="%22Wennogle+LP%22">Wennogle LP</searchLink>; Intra-Cellular Therapies, Inc. , 430 East 29th Street, Suite 900, New York, New York 10016, United States. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229716531%22">Journal of medicinal chemistry</searchLink> [J Med Chem] 2016 Feb 11; Vol. 59 (3), pp. 1149-64. <i>Date of Electronic Publication: </i>2016 Feb 02. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9716531 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-4804 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200222623%22">00222623 </searchLink><i>NLM ISO Abbreviation: </i>J Med Chem <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=26789933 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1021/acs.jmedchem.5b01751 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1149 Titles: – TitleFull: Discovery of Potent and Selective Inhibitors of Phosphodiesterase 1 for the Treatment of Cognitive Impairment Associated with Neurodegenerative and Neuropsychiatric Diseases. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Li P – PersonEntity: Name: NameFull: Zheng H – PersonEntity: Name: NameFull: Zhao J – PersonEntity: Name: NameFull: Zhang L – PersonEntity: Name: NameFull: Yao W – PersonEntity: Name: NameFull: Zhu H – PersonEntity: Name: NameFull: Beard JD – PersonEntity: Name: NameFull: Ida K – PersonEntity: Name: NameFull: Lane W – PersonEntity: Name: NameFull: Snell G – PersonEntity: Name: NameFull: Sogabe S – PersonEntity: Name: NameFull: Heyser CJ – PersonEntity: Name: NameFull: Snyder GL – PersonEntity: Name: NameFull: Hendrick JP – PersonEntity: Name: NameFull: Vanover KE – PersonEntity: Name: NameFull: Davis RE – PersonEntity: Name: NameFull: Wennogle LP IsPartOfRelationships: – BibEntity: Dates: – D: 11 M: 02 Text: 2016 Feb 11 Type: published Y: 2016 Identifiers: – Type: issn-electronic Value: 1520-4804 Numbering: – Type: volume Value: 59 – Type: issue Value: 3 Titles: – TitleFull: Journal of medicinal chemistry Type: main |
| ResultId | 1 |
