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Lower Dopamine D2 Receptor Expression Levels in Human Dopaminergic Neurons Derived From Opioid-Dependent iPSCs.

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Title: Lower Dopamine D2 Receptor Expression Levels in Human Dopaminergic Neurons Derived From Opioid-Dependent iPSCs.
Authors: Sheng Y; From the Departments of Neurological Surgery and of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland; the Intramural Research Program, Clinical Trials Treatment Branch, the Clinical Pharmacology and Therapeutics Research Branch, and the Cellular Neurobiology Branch, NIDA, Baltimore; and the Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Mass., Filichia E; From the Departments of Neurological Surgery and of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland; the Intramural Research Program, Clinical Trials Treatment Branch, the Clinical Pharmacology and Therapeutics Research Branch, and the Cellular Neurobiology Branch, NIDA, Baltimore; and the Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Mass., Shick E; From the Departments of Neurological Surgery and of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland; the Intramural Research Program, Clinical Trials Treatment Branch, the Clinical Pharmacology and Therapeutics Research Branch, and the Cellular Neurobiology Branch, NIDA, Baltimore; and the Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Mass., Preston KL; From the Departments of Neurological Surgery and of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland; the Intramural Research Program, Clinical Trials Treatment Branch, the Clinical Pharmacology and Therapeutics Research Branch, and the Cellular Neurobiology Branch, NIDA, Baltimore; and the Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Mass., Phillips KA; From the Departments of Neurological Surgery and of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland; the Intramural Research Program, Clinical Trials Treatment Branch, the Clinical Pharmacology and Therapeutics Research Branch, and the Cellular Neurobiology Branch, NIDA, Baltimore; and the Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Mass., Cooperman L; From the Departments of Neurological Surgery and of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland; the Intramural Research Program, Clinical Trials Treatment Branch, the Clinical Pharmacology and Therapeutics Research Branch, and the Cellular Neurobiology Branch, NIDA, Baltimore; and the Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Mass., Lin Z; From the Departments of Neurological Surgery and of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland; the Intramural Research Program, Clinical Trials Treatment Branch, the Clinical Pharmacology and Therapeutics Research Branch, and the Cellular Neurobiology Branch, NIDA, Baltimore; and the Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Mass., Tesar P; From the Departments of Neurological Surgery and of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland; the Intramural Research Program, Clinical Trials Treatment Branch, the Clinical Pharmacology and Therapeutics Research Branch, and the Cellular Neurobiology Branch, NIDA, Baltimore; and the Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Mass., Hoffer BJ; From the Departments of Neurological Surgery and of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland; the Intramural Research Program, Clinical Trials Treatment Branch, the Clinical Pharmacology and Therapeutics Research Branch, and the Cellular Neurobiology Branch, NIDA, Baltimore; and the Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Mass., Luo Y; From the Departments of Neurological Surgery and of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland; the Intramural Research Program, Clinical Trials Treatment Branch, the Clinical Pharmacology and Therapeutics Research Branch, and the Cellular Neurobiology Branch, NIDA, Baltimore; and the Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Mass.
Source: The American journal of psychiatry [Am J Psychiatry] 2016 Apr 01; Vol. 173 (4), pp. 429-31.
Publication Type: Letter; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
Journal Info: Publisher: American Psychiatric Association Country of Publication: United States NLM ID: 0370512 Publication Model: Print Cited Medium: Internet ISSN: 1535-7228 (Electronic) Linking ISSN: 0002953X NLM ISO Abbreviation: Am J Psychiatry Subsets: MEDLINE
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  Data: Lower Dopamine D2 Receptor Expression Levels in Human Dopaminergic Neurons Derived From Opioid-Dependent iPSCs.
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  Data: <searchLink fieldCode="AU" term="%22Sheng+Y%22">Sheng Y</searchLink>; From the Departments of Neurological Surgery and of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland; the Intramural Research Program, Clinical Trials Treatment Branch, the Clinical Pharmacology and Therapeutics Research Branch, and the Cellular Neurobiology Branch, NIDA, Baltimore; and the Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Mass.<br /><searchLink fieldCode="AU" term="%22Filichia+E%22">Filichia E</searchLink>; From the Departments of Neurological Surgery and of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland; the Intramural Research Program, Clinical Trials Treatment Branch, the Clinical Pharmacology and Therapeutics Research Branch, and the Cellular Neurobiology Branch, NIDA, Baltimore; and the Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Mass.<br /><searchLink fieldCode="AU" term="%22Shick+E%22">Shick E</searchLink>; From the Departments of Neurological Surgery and of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland; the Intramural Research Program, Clinical Trials Treatment Branch, the Clinical Pharmacology and Therapeutics Research Branch, and the Cellular Neurobiology Branch, NIDA, Baltimore; and the Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Mass.<br /><searchLink fieldCode="AU" term="%22Preston+KL%22">Preston KL</searchLink>; From the Departments of Neurological Surgery and of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland; the Intramural Research Program, Clinical Trials Treatment Branch, the Clinical Pharmacology and Therapeutics Research Branch, and the Cellular Neurobiology Branch, NIDA, Baltimore; and the Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Mass.<br /><searchLink fieldCode="AU" term="%22Phillips+KA%22">Phillips KA</searchLink>; From the Departments of Neurological Surgery and of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland; the Intramural Research Program, Clinical Trials Treatment Branch, the Clinical Pharmacology and Therapeutics Research Branch, and the Cellular Neurobiology Branch, NIDA, Baltimore; and the Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Mass.<br /><searchLink fieldCode="AU" term="%22Cooperman+L%22">Cooperman L</searchLink>; From the Departments of Neurological Surgery and of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland; the Intramural Research Program, Clinical Trials Treatment Branch, the Clinical Pharmacology and Therapeutics Research Branch, and the Cellular Neurobiology Branch, NIDA, Baltimore; and the Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Mass.<br /><searchLink fieldCode="AU" term="%22Lin+Z%22">Lin Z</searchLink>; From the Departments of Neurological Surgery and of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland; the Intramural Research Program, Clinical Trials Treatment Branch, the Clinical Pharmacology and Therapeutics Research Branch, and the Cellular Neurobiology Branch, NIDA, Baltimore; and the Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Mass.<br /><searchLink fieldCode="AU" term="%22Tesar+P%22">Tesar P</searchLink>; From the Departments of Neurological Surgery and of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland; the Intramural Research Program, Clinical Trials Treatment Branch, the Clinical Pharmacology and Therapeutics Research Branch, and the Cellular Neurobiology Branch, NIDA, Baltimore; and the Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Mass.<br /><searchLink fieldCode="AU" term="%22Hoffer+BJ%22">Hoffer BJ</searchLink>; From the Departments of Neurological Surgery and of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland; the Intramural Research Program, Clinical Trials Treatment Branch, the Clinical Pharmacology and Therapeutics Research Branch, and the Cellular Neurobiology Branch, NIDA, Baltimore; and the Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Mass.<br /><searchLink fieldCode="AU" term="%22Luo+Y%22">Luo Y</searchLink>; From the Departments of Neurological Surgery and of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland; the Intramural Research Program, Clinical Trials Treatment Branch, the Clinical Pharmacology and Therapeutics Research Branch, and the Cellular Neurobiology Branch, NIDA, Baltimore; and the Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Mass.
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  Data: <searchLink fieldCode="JN" term="%220370512%22">The American journal of psychiatry</searchLink> [Am J Psychiatry] 2016 Apr 01; Vol. 173 (4), pp. 429-31.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Psychiatric+Association%22">American Psychiatric Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0370512 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1535-7228 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220002953X%22">0002953X </searchLink><i>NLM ISO Abbreviation: </i>Am J Psychiatry <i>Subsets: </i>MEDLINE
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        Value: 10.1176/appi.ajp.2015.15121545
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      – TitleFull: Lower Dopamine D2 Receptor Expression Levels in Human Dopaminergic Neurons Derived From Opioid-Dependent iPSCs.
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              Text: 2016 Apr 01
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