A novel tumor-promoting mechanism of IL6 and the therapeutic efficacy of tocilizumab: Hypoxia-induced IL6 is a potent autophagy initiator in glioblastoma via the p-STAT3-MIR155-3p-CREBRF pathway.
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| Title: | A novel tumor-promoting mechanism of IL6 and the therapeutic efficacy of tocilizumab: Hypoxia-induced IL6 is a potent autophagy initiator in glioblastoma via the p-STAT3-MIR155-3p-CREBRF pathway. |
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| Authors: | Xue H; a Department of Neurosurgery , Qilu Hospital of Shandong University , Jinan , Shandong Province , China.; b Brain Science Research Institute, Shandong University , Jinan , Shandong Province , China., Yuan G; c Department of Neurosurgery , Central Hospital of Zibo City , Zibo , Shandong Province , China., Guo X; a Department of Neurosurgery , Qilu Hospital of Shandong University , Jinan , Shandong Province , China.; b Brain Science Research Institute, Shandong University , Jinan , Shandong Province , China., Liu Q; a Department of Neurosurgery , Qilu Hospital of Shandong University , Jinan , Shandong Province , China., Zhang J; a Department of Neurosurgery , Qilu Hospital of Shandong University , Jinan , Shandong Province , China.; b Brain Science Research Institute, Shandong University , Jinan , Shandong Province , China., Gao X; a Department of Neurosurgery , Qilu Hospital of Shandong University , Jinan , Shandong Province , China., Guo X; a Department of Neurosurgery , Qilu Hospital of Shandong University , Jinan , Shandong Province , China., Xu S; a Department of Neurosurgery , Qilu Hospital of Shandong University , Jinan , Shandong Province , China.; d Department of Neurosurgery , Dezhou People's Hospital , Dezhou , Shandong Province , China., Li T; a Department of Neurosurgery , Qilu Hospital of Shandong University , Jinan , Shandong Province , China., Shao Q; e Institute of Basic Medical Sciences and Key Laboratory of Cardiovascular Proteomics of Shandong Province, Qilu Hospital of Shandong University , Jinan , Shandong Province , China., Yan S; b Brain Science Research Institute, Shandong University , Jinan , Shandong Province , China., Li G; a Department of Neurosurgery , Qilu Hospital of Shandong University , Jinan , Shandong Province , China.; b Brain Science Research Institute, Shandong University , Jinan , Shandong Province , China. |
| Source: | Autophagy [Autophagy] 2016 Jul 02; Vol. 12 (7), pp. 1129-52. Date of Electronic Publication: 2016 May 10. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265188 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8635 (Electronic) Linking ISSN: 15548627 NLM ISO Abbreviation: Autophagy Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 27163161 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: A novel tumor-promoting mechanism of IL6 and the therapeutic efficacy of tocilizumab: Hypoxia-induced IL6 is a potent autophagy initiator in glioblastoma via the p-STAT3-MIR155-3p-CREBRF pathway. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Xue+H%22">Xue H</searchLink>; a Department of Neurosurgery , Qilu Hospital of Shandong University , Jinan , Shandong Province , China.; b Brain Science Research Institute, Shandong University , Jinan , Shandong Province , China.<br /><searchLink fieldCode="AU" term="%22Yuan+G%22">Yuan G</searchLink>; c Department of Neurosurgery , Central Hospital of Zibo City , Zibo , Shandong Province , China.<br /><searchLink fieldCode="AU" term="%22Guo+X%22">Guo X</searchLink>; a Department of Neurosurgery , Qilu Hospital of Shandong University , Jinan , Shandong Province , China.; b Brain Science Research Institute, Shandong University , Jinan , Shandong Province , China.<br /><searchLink fieldCode="AU" term="%22Liu+Q%22">Liu Q</searchLink>; a Department of Neurosurgery , Qilu Hospital of Shandong University , Jinan , Shandong Province , China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; a Department of Neurosurgery , Qilu Hospital of Shandong University , Jinan , Shandong Province , China.; b Brain Science Research Institute, Shandong University , Jinan , Shandong Province , China.<br /><searchLink fieldCode="AU" term="%22Gao+X%22">Gao X</searchLink>; a Department of Neurosurgery , Qilu Hospital of Shandong University , Jinan , Shandong Province , China.<br /><searchLink fieldCode="AU" term="%22Guo+X%22">Guo X</searchLink>; a Department of Neurosurgery , Qilu Hospital of Shandong University , Jinan , Shandong Province , China.<br /><searchLink fieldCode="AU" term="%22Xu+S%22">Xu S</searchLink>; a Department of Neurosurgery , Qilu Hospital of Shandong University , Jinan , Shandong Province , China.; d Department of Neurosurgery , Dezhou People's Hospital , Dezhou , Shandong Province , China.<br /><searchLink fieldCode="AU" term="%22Li+T%22">Li T</searchLink>; a Department of Neurosurgery , Qilu Hospital of Shandong University , Jinan , Shandong Province , China.<br /><searchLink fieldCode="AU" term="%22Shao+Q%22">Shao Q</searchLink>; e Institute of Basic Medical Sciences and Key Laboratory of Cardiovascular Proteomics of Shandong Province, Qilu Hospital of Shandong University , Jinan , Shandong Province , China.<br /><searchLink fieldCode="AU" term="%22Yan+S%22">Yan S</searchLink>; b Brain Science Research Institute, Shandong University , Jinan , Shandong Province , China.<br /><searchLink fieldCode="AU" term="%22Li+G%22">Li G</searchLink>; a Department of Neurosurgery , Qilu Hospital of Shandong University , Jinan , Shandong Province , China.; b Brain Science Research Institute, Shandong University , Jinan , Shandong Province , China. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101265188%22">Autophagy</searchLink> [Autophagy] 2016 Jul 02; Vol. 12 (7), pp. 1129-52. <i>Date of Electronic Publication: </i>2016 May 10. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Taylor+%26+Francis%22">Taylor & Francis </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101265188 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1554-8635 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215548627%22">15548627 </searchLink><i>NLM ISO Abbreviation: </i>Autophagy <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=27163161 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1080/15548627.2016.1178446 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1129 Titles: – TitleFull: A novel tumor-promoting mechanism of IL6 and the therapeutic efficacy of tocilizumab: Hypoxia-induced IL6 is a potent autophagy initiator in glioblastoma via the p-STAT3-MIR155-3p-CREBRF pathway. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Xue H – PersonEntity: Name: NameFull: Yuan G – PersonEntity: Name: NameFull: Guo X – PersonEntity: Name: NameFull: Liu Q – PersonEntity: Name: NameFull: Zhang J – PersonEntity: Name: NameFull: Gao X – PersonEntity: Name: NameFull: Guo X – PersonEntity: Name: NameFull: Xu S – PersonEntity: Name: NameFull: Li T – PersonEntity: Name: NameFull: Shao Q – PersonEntity: Name: NameFull: Yan S – PersonEntity: Name: NameFull: Li G IsPartOfRelationships: – BibEntity: Dates: – D: 02 M: 07 Text: 2016 Jul 02 Type: published Y: 2016 Identifiers: – Type: issn-electronic Value: 1554-8635 Numbering: – Type: volume Value: 12 – Type: issue Value: 7 Titles: – TitleFull: Autophagy Type: main |
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