Flexibility is important for inhibition of the MDM2/p53 protein-protein interaction by cyclic β-hairpins.

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Title: Flexibility is important for inhibition of the MDM2/p53 protein-protein interaction by cyclic β-hairpins.
Authors: Danelius E; Department of Chemistry and Molecular Biology, University of Gothenburg, SE-41296 Gothenburg, Sweden. grotli@chem.gu.se mate@chem.gu.se., Pettersson M; Department of Chemistry and Molecular Biology, University of Gothenburg, SE-41296 Gothenburg, Sweden. grotli@chem.gu.se mate@chem.gu.se., Bred M; Department of Chemistry and Molecular Biology, University of Gothenburg, SE-41296 Gothenburg, Sweden. grotli@chem.gu.se mate@chem.gu.se., Min J; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, Tennessee 38105, USA., Waddell MB; Molecular Interaction Analysis Shared Resource, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, Tennessee 38105, USA., Guy RK; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, Tennessee 38105, USA., Grøtli M; Department of Chemistry and Molecular Biology, University of Gothenburg, SE-41296 Gothenburg, Sweden. grotli@chem.gu.se mate@chem.gu.se., Erdelyi M; Department of Chemistry and Molecular Biology, University of Gothenburg, SE-41296 Gothenburg, Sweden. grotli@chem.gu.se mate@chem.gu.se and Swedish NMR Centre, Medicinaregatan 5, SE-41390 Gothenburg, Sweden.
Source: Organic & biomolecular chemistry [Org Biomol Chem] 2016 Nov 08; Vol. 14 (44), pp. 10386-10393.
Publication Type: Journal Article
Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101154995 Publication Model: Print Cited Medium: Internet ISSN: 1477-0539 (Electronic) Linking ISSN: 14770520 NLM ISO Abbreviation: Org Biomol Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Danelius+E%22">Danelius E</searchLink>; Department of Chemistry and Molecular Biology, University of Gothenburg, SE-41296 Gothenburg, Sweden. grotli@chem.gu.se mate@chem.gu.se.<br /><searchLink fieldCode="AU" term="%22Pettersson+M%22">Pettersson M</searchLink>; Department of Chemistry and Molecular Biology, University of Gothenburg, SE-41296 Gothenburg, Sweden. grotli@chem.gu.se mate@chem.gu.se.<br /><searchLink fieldCode="AU" term="%22Bred+M%22">Bred M</searchLink>; Department of Chemistry and Molecular Biology, University of Gothenburg, SE-41296 Gothenburg, Sweden. grotli@chem.gu.se mate@chem.gu.se.<br /><searchLink fieldCode="AU" term="%22Min+J%22">Min J</searchLink>; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, Tennessee 38105, USA.<br /><searchLink fieldCode="AU" term="%22Waddell+MB%22">Waddell MB</searchLink>; Molecular Interaction Analysis Shared Resource, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, Tennessee 38105, USA.<br /><searchLink fieldCode="AU" term="%22Guy+RK%22">Guy RK</searchLink>; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, Tennessee 38105, USA.<br /><searchLink fieldCode="AU" term="%22Grøtli+M%22">Grøtli M</searchLink>; Department of Chemistry and Molecular Biology, University of Gothenburg, SE-41296 Gothenburg, Sweden. grotli@chem.gu.se mate@chem.gu.se.<br /><searchLink fieldCode="AU" term="%22Erdelyi+M%22">Erdelyi M</searchLink>; Department of Chemistry and Molecular Biology, University of Gothenburg, SE-41296 Gothenburg, Sweden. grotli@chem.gu.se mate@chem.gu.se and Swedish NMR Centre, Medicinaregatan 5, SE-41390 Gothenburg, Sweden.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Royal+Society+of+Chemistry%22">Royal Society of Chemistry </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101154995 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1477-0539 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214770520%22">14770520 </searchLink><i>NLM ISO Abbreviation: </i>Org Biomol Chem <i>Subsets: </i>MEDLINE
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              Text: 2016 Nov 08
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