Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell-associated damage in IFNα-driven lupus nephritis.
Saved in:
| Title: | Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell-associated damage in IFNα-driven lupus nephritis. |
|---|---|
| Authors: | Katewa A; Departments of Immunology Discovery., Wang Y; Departments of Immunology Discovery., Hackney JA; Bioinformatics and Computational Biology., Huang T; Departments of Immunology Discovery., Suto E; Translational Immunology., Ramamoorthi N; Biomarker Discovery OMNI., Austin CD; Pathology., Bremer M; Biomarker Development., Chen JZ; Drug Metabolism and Pharmacokinetics., Crawford JJ; Discovery Chemistry, at Genentech, South San Francisco, California, USA., Currie KS; Gilead Sciences, Seattle, Washington, USA., Blomgren P; Gilead Sciences, Seattle, Washington, USA., DeVoss J; Translational Immunology., DiPaolo JA; Gilead Sciences, Foster City, California, USA., Hau J; Small Molecule Pharmaceutical Sciences., Johnson A; Biochemical and Cellular Pharmacology., Lesch J; Translational Immunology., DeForge LE; Biochemical and Cellular Pharmacology., Lin Z; Translational Immunology., Liimatta M; Biochemical and Cellular Pharmacology., Lubach JW; Small Molecule Pharmaceutical Sciences., McVay S; Biochemical and Cellular Pharmacology., Modrusan Z; Molecular Biology., Nguyen A; Biochemical and Cellular Pharmacology., Poon C; Departments of Immunology Discovery., Wang J; Biochemical and Cellular Pharmacology., Liu L; Clinical Pharmacology at Genentech, South San Francisco, California, USA., Lee WP; Translational Immunology., Wong H; Drug Metabolism and Pharmacokinetics., Young WB; Discovery Chemistry, at Genentech, South San Francisco, California, USA., Townsend MJ; Biomarker Discovery OMNI., Reif K; Departments of Immunology Discovery. |
| Source: | JCI insight [JCI Insight] 2017 Apr 06; Vol. 2 (7), pp. e90111. Date of Electronic Publication: 2017 Apr 06. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
Be the first to leave a comment!
