An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
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| Title: | An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. |
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| Authors: | Scott RA; MRC Epidemiology Unit, University of Cambridge, Cambridge, U.K., Scott LJ; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI., Mägi R; Estonian Genome Center, University of Tartu, Tartu, Estonia., Marullo L; Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy., Gaulton KJ; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.; Department of Genetics, Stanford University, Stanford, CA., Kaakinen M; Department of Genomics of Common Disease, Imperial College London, London, U.K., Pervjakova N; Estonian Genome Center, University of Tartu, Tartu, Estonia., Pers TH; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Johnson AD; Framingham Heart Study, Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Framingham, MA., Eicher JD; Framingham Heart Study, Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Framingham, MA., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI., Ferreira T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K., Lee Y; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI., Ma C; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI., Steinthorsdottir V; deCODE genetics, Amgen, Inc., Reykjavik, Iceland., Thorleifsson G; deCODE genetics, Amgen, Inc., Reykjavik, Iceland., Qi L; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA., Van Zuydam NR; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.; Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics and Biomedical Research Institute, Ninewells Hospital, University of Dundee, Dundee, U.K., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K., Chen H; Human Genetics Center and Department of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX.; Center for Precision Health, School Biomedical Informatics, and School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX., Almgren P; Lund University Diabetes Centre and Department of Clinical Sciences Malmö, University Hospital Scania, Lund University, Malmö, Sweden., Voight BF; Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.; Institute of Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Grallert H; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany.; Genetic Epidemiology, Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany.; Munich Heart Alliance, German Centre for Cardiovascular Disease, Munich, Germany., Ried JS; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Rayner NW; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, U.K.; Wellcome Trust Sanger Institute, Hinxton, U.K., Robertson N; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, U.K., Karssen LC; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.; PolyOmica, 's-Hertogenbosch, the Netherlands., van Leeuwen EM; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Willems SM; MRC Epidemiology Unit, University of Cambridge, Cambridge, U.K.; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Fuchsberger C; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI., Kwan P; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI., Teslovich TM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI., Chanda P; High Throughput Biology Center, Johns Hopkins University School of Medicine, Baltimore, MD., Li M; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD., Lu Y; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.; The Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY., Dina C; l'institut du thorax, INSERM, CNRS, Centre Hospitalier Universitaire de Nantes, Université de Nantes, Nantes, France., Thuillier D; Lille Institute of Biology, European Genomics Institute of Diabetes, Lille, France.; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France., Yengo L; Lille Institute of Biology, European Genomics Institute of Diabetes, Lille, France.; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France., Jiang L; Department of Genomics of Common Disease, Imperial College London, London, U.K., Sparso T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kestler HA; Leibniz Institute on Aging, Fritz Lipmann Institute, Jena, Germany.; Institute of Medical Systems Biology, Ulm University, Ulm, Germany., Chheda H; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Eisele L; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany., Gustafsson S; Molecular Epidemiology, Department of Medical Sciences, and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Frånberg M; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Science for Life Laboratory, Stockholm, Sweden.; Department for Numerical Analysis and Computer Science, Stockholm University, Stockholm, Sweden., Strawbridge RJ; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Benediktsson R; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Landspítali University Hospital, Reykjavik, Iceland., Hreidarsson AB; Landspítali University Hospital, Reykjavik, Iceland., Kong A; deCODE genetics, Amgen, Inc., Reykjavik, Iceland., Sigurðsson G; Landspítali University Hospital, Reykjavik, Iceland.; Icelandic Heart Association, Kópavogur, Iceland., Kerrison ND; MRC Epidemiology Unit, University of Cambridge, Cambridge, U.K., Luan J; MRC Epidemiology Unit, University of Cambridge, Cambridge, U.K., Liang L; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA., Meitinger T; Munich Heart Alliance, German Centre for Cardiovascular Disease, Munich, Germany.; Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany.; Institute of Human Genetics, Technische Universität München, Munich, Germany., Roden M; German Center for Diabetes Research, Neuherberg, Germany.; Department of Endocrinology and Diabetology, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Institute for Diabetes Research at Heinrich-Heine University Düsseldorf, Düsseldorf, Germany., Thorand B; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Esko T; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA.; Division of Genetics and Endocrinology, Boston Children's Hospital, Boston, MA., Mihailov E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Fox C; Framingham Heart Study, National Heart, Lung, and Blood Institute, Framingham, MA.; Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, MA., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA., Rybin D; Data Coordinating Center, Boston University School of Public Health, Boston, MA., Isomaa B; Folkhälsan Research Center, Helsinki, Finland.; Department of Social Services and Health Care, Jakobstad, Finland., Lyssenko V; Lund University Diabetes Centre and Department of Clinical Sciences Malmö, University Hospital Scania, Lund University, Malmö, Sweden., Tuomi T; Folkhälsan Research Center, Helsinki, Finland.; Department of Medicine, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Couper DJ; Collaborative Studies Coordinating Center, Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC., Pankow JS; Division of Epidemiology & Community Health, University of Minnesota, Minneapolis, MN., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Have CT; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Jørgensen ME; Steno Diabetes Center, Gentofte, Denmark., Jørgensen T; Research Centre for Prevention and Health, Capital Region of Denmark, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Faculty of Medicine, Aalborg University, Aalborg, Denmark., Linneberg A; Research Centre for Prevention and Health, Capital Region of Denmark, Copenhagen, Denmark.; Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Cornelis MC; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL., van Dam RM; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore., Hunter DJ; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA., Kraft P; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA., Sun Q; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA., Edkins S; Wellcome Trust Sanger Institute, Hinxton, U.K., Owen KR; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, U.K.; National Institute for Health Research Oxford Biomedical Research Centre, Churchill Hospital, Oxford, U.K., Perry JRB; MRC Epidemiology Unit, University of Cambridge, Cambridge, U.K., Wood AR; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, U.K., Zeggini E; Wellcome Trust Sanger Institute, Hinxton, U.K., Tajes-Fernandes J; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K., Abecasis GR; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI., Bonnycastle LL; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD., Chines PS; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI., Koistinen HA; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Endocrinology, Department of Medicine and Abdominal Center, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Biomedicum Helsinki 2U, Helsinki, Finland., Kinnunen L; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Endocrinology, Department of Medicine and Abdominal Center, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Biomedicum Helsinki 2U, Helsinki, Finland., Sennblad B; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Science for Life Laboratory, Stockholm, Sweden., Mühleisen TW; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany., Nöthen MM; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany., Pechlivanis S; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany., Baldassarre D; Centro Cardiologico Monzino, Istituto di Ricovero e Cura a Carattere Scientifico, Milan, Italy.; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy., Gertow K; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Humphries SE; Cardiovascular Genetics, BHF Laboratories, Institute Cardiovascular Sciences, University College London, London, U.K., Tremoli E; Centro Cardiologico Monzino, Istituto di Ricovero e Cura a Carattere Scientifico, Milan, Italy.; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy., Klopp N; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany., Meyer J; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Steinbach G; Department of Clinical Chemistry and Central Laboratory, University of Ulm, Ulm, Germany., Wennauer R; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Eriksson JG; Folkhälsan Research Center, Helsinki, Finland.; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.; Unit of General Practice, Helsinki University Central Hospital, Helsinki, Finland., Mӓnnistö S; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland., Peltonen L; Wellcome Trust Sanger Institute, Hinxton, U.K.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.; Broad Institute of MIT and Harvard, Cambridge, MA., Tikkanen E; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.; Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki, Finland., Charpentier G; Endocrinology-Diabetology Unit, Corbeil-Essonnes Hospital, Corbeil-Essonnes, France., Eury E; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France., Lobbens S; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France., Gigante B; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Leander K; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., McLeod O; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY., Gottesman O; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY., Ruderfer D; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY., Blüher M; IFB AdiposityDiseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Kovacs P; IFB AdiposityDiseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Tonjes A; IFB AdiposityDiseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Maruthur NM; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.; Division of General Internal Medicine, Department of Medicine, Johns Hopkins Bloomberg School of Medicine, Baltimore, MD.; The Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University, Baltimore, MD., Scapoli C; Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy., Erbel R; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany., Jöckel KH; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany., Moebus S; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany., de Faire U; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Hamsten A; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Stumvoll M; IFB AdiposityDiseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Deloukas P; Wellcome Trust Sanger Institute, Hinxton, U.K.; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University London, London, U.K., Donnelly PJ; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.; Department of Statistics, University of Oxford, Oxford, U.K., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, U.K., Hattersley AT; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, U.K., Ripatti S; Wellcome Trust Sanger Institute, Hinxton, U.K.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.; Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki, Finland.; Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland., Salomaa V; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Boehm BO; Division of Endocrinology and Diabetes, Department of Internal Medicine, University Medical Centre Ulm, Ulm, Germany.; Lee Kong Chian School of Medicine, Imperial College London and Nanyang Technological University, Singapore, Singapore., Bergman RN; Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA., Collins FS; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC., Tuomilehto J; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.; Dasman Diabetes Institute, Dasman, Kuwait.; Centre for Vascular Prevention, Danube University Krems, Krems, Austria.; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Barroso I; Wellcome Trust Sanger Institute, Hinxton, U.K.; University of Cambridge Metabolic Research Laboratories and National Institute for Health Research Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital Cambridge, Cambridge, U.K., Lannfelt L; Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden., Ingelsson E; Molecular Epidemiology, Department of Medical Sciences, and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA., Lind L; Cardiovascular Epidemiology, Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.; Broad Institute of MIT and Harvard, Cambridge, MA., Cauchi S; Lille Institute of Biology, European Genomics Institute of Diabetes, Lille, France., Froguel P; Department of Genomics of Common Disease, Imperial College London, London, U.K.; Lille Institute of Biology, European Genomics Institute of Diabetes, Lille, France.; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.; The Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY., Balkau B; INSERM, CESP, UMR 1018, Villejuif, France.; University of Paris-Sud, UMR 1018, Villejuif, France., Boeing H; German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany., Franks PW; Lund University, Malmö, Sweden.; Umeå University, Umeå, Sweden., Barricarte Gurrea A; Navarra Public Health Institute, Pamplona, Spain.; Navarra Institute for Health Research, Pamplona, Spain.; CIBER Epidemiology and Public Health, Madrid, Spain., Palli D; Cancer Research and Prevention Institute, Florence, Italy., van der Schouw YT; University Medical Center Utrecht, Utrecht, the Netherlands., Altshuler D; Broad Institute of MIT and Harvard, Cambridge, MA.; Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA.; Department of Medicine, Harvard Medical School, Boston, MA.; Department of Genetics, Harvard Medical School, Boston, MA.; Department of Molecular Biology, Harvard Medical School, Boston, MA.; Diabetes Unit, Massachusetts General Hospital, Boston, MA., Groop LC; Lund University Diabetes Centre and Department of Clinical Sciences Malmö, University Hospital Scania, Lund University, Malmö, Sweden.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Langenberg C; MRC Epidemiology Unit, University of Cambridge, Cambridge, U.K., Wareham NJ; MRC Epidemiology Unit, University of Cambridge, Cambridge, U.K., Sijbrands E; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., van Duijn CM; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Netherlands Genomics Initiative, Netherlands Consortium for Healthy Ageing and Center for Medical Systems Biology, Rotterdam, the Netherlands., Florez JC; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA.; Department of Medicine, Harvard Medical School, Boston, MA.; Diabetes Unit and Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA., Meigs JB; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA.; Department of Medicine, Harvard Medical School, Boston, MA.; General Medicine Division, Massachusetts General Hospital, Boston, MA., Boerwinkle E; Human Genetics Center, The University of Texas Health Science Center at Houston, Houston, TX.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Genetic Epidemiology, Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia., Morris AD; Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, U.K., Palmer CNA; Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics and Biomedical Research Institute, Ninewells Hospital, University of Dundee, Dundee, U.K.; Cardiovascular and Diabetes Medicine, Biomedical Research Institute, Ninewells Hospital, University of Dundee, Dundee, U.K., Hu FB; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA., Thorsteinsdottir U; deCODE genetics, Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Stefansson K; deCODE genetics, Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Dupuis J; Framingham Heart Study, National Heart, Lung, and Blood Institute, Framingham, MA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA., Morris AP; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.; Department of Biostatistics, University of Liverpool, Liverpool, U.K.; Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, U.K., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI boehnke@umich.edu., McCarthy MI; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K. mark.mccarthy@drl.ox.ac.uk.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, U.K.; National Institute for Health Research Oxford Biomedical Research Centre, Churchill Hospital, Oxford, U.K., Prokopenko I; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K. i.prokopenko@imperial.ac.uk.; Department of Genomics of Common Disease, Imperial College London, London, U.K.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, U.K. |
| Corporate Authors: | DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium |
| Source: | Diabetes [Diabetes] 2017 Nov; Vol. 66 (11), pp. 2888-2902. Date of Electronic Publication: 2017 May 31. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-327X (Electronic) Linking ISSN: 00121797 NLM ISO Abbreviation: Diabetes Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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