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Teriflunomide slows BVL in relapsing MS: A reanalysis of the TEMSO MRI data set using SIENA.

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Title: Teriflunomide slows BVL in relapsing MS: A reanalysis of the TEMSO MRI data set using SIENA.
Authors: Radue EW; Medical Image Analysis Center (MIAC AG) (E.-W.R., L.G., N.M.-L., J.W.), Basel, Switzerland; DKD HELIOS Klinik (T.S.), Wiesbaden, Germany; Neurologic Clinic and Policlinic (T.S., L.G., L.K.), University Hospital Basel and University of Basel, Switzerland; Sanofi Genzyme (S.C., K.T.), Previously Sanofi Genzyme (M.A.P.), and WAVE Life Sciences (M.A.P.), Cambridge, MA; Fishawack Communications Ltd (J.E.D., F.M.W.), Abingdon, Oxfordshire, UK; and McGovern Medical School (J.S.W.), UTHealth, Houston, TX., Sprenger T; Medical Image Analysis Center (MIAC AG) (E.-W.R., L.G., N.M.-L., J.W.), Basel, Switzerland; DKD HELIOS Klinik (T.S.), Wiesbaden, Germany; Neurologic Clinic and Policlinic (T.S., L.G., L.K.), University Hospital Basel and University of Basel, Switzerland; Sanofi Genzyme (S.C., K.T.), Previously Sanofi Genzyme (M.A.P.), and WAVE Life Sciences (M.A.P.), Cambridge, MA; Fishawack Communications Ltd (J.E.D., F.M.W.), Abingdon, Oxfordshire, UK; and McGovern Medical School (J.S.W.), UTHealth, Houston, TX., Gaetano L; Medical Image Analysis Center (MIAC AG) (E.-W.R., L.G., N.M.-L., J.W.), Basel, Switzerland; DKD HELIOS Klinik (T.S.), Wiesbaden, Germany; Neurologic Clinic and Policlinic (T.S., L.G., L.K.), University Hospital Basel and University of Basel, Switzerland; Sanofi Genzyme (S.C., K.T.), Previously Sanofi Genzyme (M.A.P.), and WAVE Life Sciences (M.A.P.), Cambridge, MA; Fishawack Communications Ltd (J.E.D., F.M.W.), Abingdon, Oxfordshire, UK; and McGovern Medical School (J.S.W.), UTHealth, Houston, TX., Mueller-Lenke N; Medical Image Analysis Center (MIAC AG) (E.-W.R., L.G., N.M.-L., J.W.), Basel, Switzerland; DKD HELIOS Klinik (T.S.), Wiesbaden, Germany; Neurologic Clinic and Policlinic (T.S., L.G., L.K.), University Hospital Basel and University of Basel, Switzerland; Sanofi Genzyme (S.C., K.T.), Previously Sanofi Genzyme (M.A.P.), and WAVE Life Sciences (M.A.P.), Cambridge, MA; Fishawack Communications Ltd (J.E.D., F.M.W.), Abingdon, Oxfordshire, UK; and McGovern Medical School (J.S.W.), UTHealth, Houston, TX., Cavalier S; Medical Image Analysis Center (MIAC AG) (E.-W.R., L.G., N.M.-L., J.W.), Basel, Switzerland; DKD HELIOS Klinik (T.S.), Wiesbaden, Germany; Neurologic Clinic and Policlinic (T.S., L.G., L.K.), University Hospital Basel and University of Basel, Switzerland; Sanofi Genzyme (S.C., K.T.), Previously Sanofi Genzyme (M.A.P.), and WAVE Life Sciences (M.A.P.), Cambridge, MA; Fishawack Communications Ltd (J.E.D., F.M.W.), Abingdon, Oxfordshire, UK; and McGovern Medical School (J.S.W.), UTHealth, Houston, TX., Thangavelu K; Medical Image Analysis Center (MIAC AG) (E.-W.R., L.G., N.M.-L., J.W.), Basel, Switzerland; DKD HELIOS Klinik (T.S.), Wiesbaden, Germany; Neurologic Clinic and Policlinic (T.S., L.G., L.K.), University Hospital Basel and University of Basel, Switzerland; Sanofi Genzyme (S.C., K.T.), Previously Sanofi Genzyme (M.A.P.), and WAVE Life Sciences (M.A.P.), Cambridge, MA; Fishawack Communications Ltd (J.E.D., F.M.W.), Abingdon, Oxfordshire, UK; and McGovern Medical School (J.S.W.), UTHealth, Houston, TX., Panzara MA; Medical Image Analysis Center (MIAC AG) (E.-W.R., L.G., N.M.-L., J.W.), Basel, Switzerland; DKD HELIOS Klinik (T.S.), Wiesbaden, Germany; Neurologic Clinic and Policlinic (T.S., L.G., L.K.), University Hospital Basel and University of Basel, Switzerland; Sanofi Genzyme (S.C., K.T.), Previously Sanofi Genzyme (M.A.P.), and WAVE Life Sciences (M.A.P.), Cambridge, MA; Fishawack Communications Ltd (J.E.D., F.M.W.), Abingdon, Oxfordshire, UK; and McGovern Medical School (J.S.W.), UTHealth, Houston, TX., Donaldson JE; Medical Image Analysis Center (MIAC AG) (E.-W.R., L.G., N.M.-L., J.W.), Basel, Switzerland; DKD HELIOS Klinik (T.S.), Wiesbaden, Germany; Neurologic Clinic and Policlinic (T.S., L.G., L.K.), University Hospital Basel and University of Basel, Switzerland; Sanofi Genzyme (S.C., K.T.), Previously Sanofi Genzyme (M.A.P.), and WAVE Life Sciences (M.A.P.), Cambridge, MA; Fishawack Communications Ltd (J.E.D., F.M.W.), Abingdon, Oxfordshire, UK; and McGovern Medical School (J.S.W.), UTHealth, Houston, TX., Woodward FM; Medical Image Analysis Center (MIAC AG) (E.-W.R., L.G., N.M.-L., J.W.), Basel, Switzerland; DKD HELIOS Klinik (T.S.), Wiesbaden, Germany; Neurologic Clinic and Policlinic (T.S., L.G., L.K.), University Hospital Basel and University of Basel, Switzerland; Sanofi Genzyme (S.C., K.T.), Previously Sanofi Genzyme (M.A.P.), and WAVE Life Sciences (M.A.P.), Cambridge, MA; Fishawack Communications Ltd (J.E.D., F.M.W.), Abingdon, Oxfordshire, UK; and McGovern Medical School (J.S.W.), UTHealth, Houston, TX., Wuerfel J; Medical Image Analysis Center (MIAC AG) (E.-W.R., L.G., N.M.-L., J.W.), Basel, Switzerland; DKD HELIOS Klinik (T.S.), Wiesbaden, Germany; Neurologic Clinic and Policlinic (T.S., L.G., L.K.), University Hospital Basel and University of Basel, Switzerland; Sanofi Genzyme (S.C., K.T.), Previously Sanofi Genzyme (M.A.P.), and WAVE Life Sciences (M.A.P.), Cambridge, MA; Fishawack Communications Ltd (J.E.D., F.M.W.), Abingdon, Oxfordshire, UK; and McGovern Medical School (J.S.W.), UTHealth, Houston, TX., Wolinsky JS; Medical Image Analysis Center (MIAC AG) (E.-W.R., L.G., N.M.-L., J.W.), Basel, Switzerland; DKD HELIOS Klinik (T.S.), Wiesbaden, Germany; Neurologic Clinic and Policlinic (T.S., L.G., L.K.), University Hospital Basel and University of Basel, Switzerland; Sanofi Genzyme (S.C., K.T.), Previously Sanofi Genzyme (M.A.P.), and WAVE Life Sciences (M.A.P.), Cambridge, MA; Fishawack Communications Ltd (J.E.D., F.M.W.), Abingdon, Oxfordshire, UK; and McGovern Medical School (J.S.W.), UTHealth, Houston, TX., Kappos L; Medical Image Analysis Center (MIAC AG) (E.-W.R., L.G., N.M.-L., J.W.), Basel, Switzerland; DKD HELIOS Klinik (T.S.), Wiesbaden, Germany; Neurologic Clinic and Policlinic (T.S., L.G., L.K.), University Hospital Basel and University of Basel, Switzerland; Sanofi Genzyme (S.C., K.T.), Previously Sanofi Genzyme (M.A.P.), and WAVE Life Sciences (M.A.P.), Cambridge, MA; Fishawack Communications Ltd (J.E.D., F.M.W.), Abingdon, Oxfordshire, UK; and McGovern Medical School (J.S.W.), UTHealth, Houston, TX.
Source: Neurology(R) neuroimmunology & neuroinflammation [Neurol Neuroimmunol Neuroinflamm] 2017 Aug 09; Vol. 4 (5), pp. e390. Date of Electronic Publication: 2017 Aug 09 (Print Publication: 2017).
Publication Type: Journal Article
Journal Info: Publisher: Wolters Kluwer Health/Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101636388 Publication Model: eCollection Cited Medium: Print ISSN: 2332-7812 (Print) Linking ISSN: 23327812 NLM ISO Abbreviation: Neurol Neuroimmunol Neuroinflamm Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Teriflunomide slows BVL in relapsing MS: A reanalysis of the TEMSO MRI data set using SIENA.
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  Data: <searchLink fieldCode="AU" term="%22Radue+EW%22">Radue EW</searchLink>; Medical Image Analysis Center (MIAC AG) (E.-W.R., L.G., N.M.-L., J.W.), Basel, Switzerland; DKD HELIOS Klinik (T.S.), Wiesbaden, Germany; Neurologic Clinic and Policlinic (T.S., L.G., L.K.), University Hospital Basel and University of Basel, Switzerland; Sanofi Genzyme (S.C., K.T.), Previously Sanofi Genzyme (M.A.P.), and WAVE Life Sciences (M.A.P.), Cambridge, MA; Fishawack Communications Ltd (J.E.D., F.M.W.), Abingdon, Oxfordshire, UK; and McGovern Medical School (J.S.W.), UTHealth, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Sprenger+T%22">Sprenger T</searchLink>; Medical Image Analysis Center (MIAC AG) (E.-W.R., L.G., N.M.-L., J.W.), Basel, Switzerland; DKD HELIOS Klinik (T.S.), Wiesbaden, Germany; Neurologic Clinic and Policlinic (T.S., L.G., L.K.), University Hospital Basel and University of Basel, Switzerland; Sanofi Genzyme (S.C., K.T.), Previously Sanofi Genzyme (M.A.P.), and WAVE Life Sciences (M.A.P.), Cambridge, MA; 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Sanofi Genzyme (S.C., K.T.), Previously Sanofi Genzyme (M.A.P.), and WAVE Life Sciences (M.A.P.), Cambridge, MA; Fishawack Communications Ltd (J.E.D., F.M.W.), Abingdon, Oxfordshire, UK; and McGovern Medical School (J.S.W.), UTHealth, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Cavalier+S%22">Cavalier S</searchLink>; Medical Image Analysis Center (MIAC AG) (E.-W.R., L.G., N.M.-L., J.W.), Basel, Switzerland; DKD HELIOS Klinik (T.S.), Wiesbaden, Germany; Neurologic Clinic and Policlinic (T.S., L.G., L.K.), University Hospital Basel and University of Basel, Switzerland; Sanofi Genzyme (S.C., K.T.), Previously Sanofi Genzyme (M.A.P.), and WAVE Life Sciences (M.A.P.), Cambridge, MA; Fishawack Communications Ltd (J.E.D., F.M.W.), Abingdon, Oxfordshire, UK; and McGovern Medical School (J.S.W.), UTHealth, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Thangavelu+K%22">Thangavelu K</searchLink>; Medical Image Analysis Center (MIAC AG) (E.-W.R., L.G., N.M.-L., J.W.), Basel, Switzerland; 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Medical Image Analysis Center (MIAC AG) (E.-W.R., L.G., N.M.-L., J.W.), Basel, Switzerland; DKD HELIOS Klinik (T.S.), Wiesbaden, Germany; Neurologic Clinic and Policlinic (T.S., L.G., L.K.), University Hospital Basel and University of Basel, Switzerland; Sanofi Genzyme (S.C., K.T.), Previously Sanofi Genzyme (M.A.P.), and WAVE Life Sciences (M.A.P.), Cambridge, MA; Fishawack Communications Ltd (J.E.D., F.M.W.), Abingdon, Oxfordshire, UK; and McGovern Medical School (J.S.W.), UTHealth, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Woodward+FM%22">Woodward FM</searchLink>; Medical Image Analysis Center (MIAC AG) (E.-W.R., L.G., N.M.-L., J.W.), Basel, Switzerland; DKD HELIOS Klinik (T.S.), Wiesbaden, Germany; Neurologic Clinic and Policlinic (T.S., L.G., L.K.), University Hospital Basel and University of Basel, Switzerland; Sanofi Genzyme (S.C., K.T.), Previously Sanofi Genzyme (M.A.P.), and WAVE Life Sciences (M.A.P.), Cambridge, MA; Fishawack Communications Ltd (J.E.D., F.M.W.), Abingdon, Oxfordshire, UK; and McGovern Medical School (J.S.W.), UTHealth, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Wuerfel+J%22">Wuerfel J</searchLink>; Medical Image Analysis Center (MIAC AG) (E.-W.R., L.G., N.M.-L., J.W.), Basel, Switzerland; DKD HELIOS Klinik (T.S.), Wiesbaden, Germany; Neurologic Clinic and Policlinic (T.S., L.G., L.K.), University Hospital Basel and University of Basel, Switzerland; Sanofi Genzyme (S.C., K.T.), Previously Sanofi Genzyme (M.A.P.), and WAVE Life Sciences (M.A.P.), Cambridge, MA; Fishawack Communications Ltd (J.E.D., F.M.W.), Abingdon, Oxfordshire, UK; and McGovern Medical School (J.S.W.), UTHealth, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Wolinsky+JS%22">Wolinsky JS</searchLink>; Medical Image Analysis Center (MIAC AG) (E.-W.R., L.G., N.M.-L., J.W.), Basel, Switzerland; DKD HELIOS Klinik (T.S.), Wiesbaden, Germany; Neurologic Clinic and Policlinic (T.S., L.G., L.K.), University Hospital Basel and University of Basel, Switzerland; Sanofi Genzyme (S.C., K.T.), Previously Sanofi Genzyme (M.A.P.), and WAVE Life Sciences (M.A.P.), Cambridge, MA; Fishawack Communications Ltd (J.E.D., F.M.W.), Abingdon, Oxfordshire, UK; and McGovern Medical School (J.S.W.), UTHealth, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Kappos+L%22">Kappos L</searchLink>; Medical Image Analysis Center (MIAC AG) (E.-W.R., L.G., N.M.-L., J.W.), Basel, Switzerland; DKD HELIOS Klinik (T.S.), Wiesbaden, Germany; Neurologic Clinic and Policlinic (T.S., L.G., L.K.), University Hospital Basel and University of Basel, Switzerland; Sanofi Genzyme (S.C., K.T.), Previously Sanofi Genzyme (M.A.P.), and WAVE Life Sciences (M.A.P.), Cambridge, MA; Fishawack Communications Ltd (J.E.D., F.M.W.), Abingdon, Oxfordshire, UK; and McGovern Medical School (J.S.W.), UTHealth, Houston, TX.
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  Data: <searchLink fieldCode="JN" term="%22101636388%22">Neurology(R) neuroimmunology & neuroinflammation</searchLink> [Neurol Neuroimmunol Neuroinflamm] 2017 Aug 09; Vol. 4 (5), pp. e390. <i>Date of Electronic Publication: </i>2017 Aug 09 (<i>Print Publication: </i>2017).
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        Value: 10.1212/NXI.0000000000000390
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        Text: English
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      – TitleFull: Teriflunomide slows BVL in relapsing MS: A reanalysis of the TEMSO MRI data set using SIENA.
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              Text: 2017 Aug 09
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            – TitleFull: Neurology(R) neuroimmunology & neuroinflammation
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