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Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity.

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Title: Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity.
Authors: Kazak L; Dana-Farber Cancer Institute, Boston, MA 02115, USA; Department of Cell Biology, Harvard University Medical School, Boston, MA 02115, USA. Electronic address: lawrence.kazak@mcgill.ca., Chouchani ET; Dana-Farber Cancer Institute, Boston, MA 02115, USA; Department of Cell Biology, Harvard University Medical School, Boston, MA 02115, USA., Lu GZ; Dana-Farber Cancer Institute, Boston, MA 02115, USA., Jedrychowski MP; Department of Cell Biology, Harvard University Medical School, Boston, MA 02115, USA., Bare CJ; Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Mina AI; Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Kumari M; Division of Endocrinology, Beth Israel Deaconess Medical Center and Department of Genetics, Harvard Medical School, Boston, MA 02215, USA., Zhang S; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA., Vuckovic I; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA., Laznik-Bogoslavski D; Dana-Farber Cancer Institute, Boston, MA 02115, USA., Dzeja P; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA., Banks AS; Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Rosen ED; Division of Endocrinology, Beth Israel Deaconess Medical Center and Department of Genetics, Harvard Medical School, Boston, MA 02215, USA., Spiegelman BM; Dana-Farber Cancer Institute, Boston, MA 02115, USA; Department of Cell Biology, Harvard University Medical School, Boston, MA 02115, USA. Electronic address: bruce_spiegelman@dfci.harvard.edu.
Source: Cell metabolism [Cell Metab] 2017 Oct 03; Vol. 26 (4), pp. 660-671.e3. Date of Electronic Publication: 2017 Aug 24.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE
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  Data: Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity.
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  Data: <searchLink fieldCode="AU" term="%22Kazak+L%22">Kazak L</searchLink>; Dana-Farber Cancer Institute, Boston, MA 02115, USA; Department of Cell Biology, Harvard University Medical School, Boston, MA 02115, USA. Electronic address: lawrence.kazak@mcgill.ca.<br /><searchLink fieldCode="AU" term="%22Chouchani+ET%22">Chouchani ET</searchLink>; Dana-Farber Cancer Institute, Boston, MA 02115, USA; Department of Cell Biology, Harvard University Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Lu+GZ%22">Lu GZ</searchLink>; Dana-Farber Cancer Institute, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Jedrychowski+MP%22">Jedrychowski MP</searchLink>; Department of Cell Biology, Harvard University Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Bare+CJ%22">Bare CJ</searchLink>; Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Mina+AI%22">Mina AI</searchLink>; Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Kumari+M%22">Kumari M</searchLink>; Division of Endocrinology, Beth Israel Deaconess Medical Center and Department of Genetics, Harvard Medical School, Boston, MA 02215, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Vuckovic+I%22">Vuckovic I</searchLink>; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Laznik-Bogoslavski+D%22">Laznik-Bogoslavski D</searchLink>; Dana-Farber Cancer Institute, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Dzeja+P%22">Dzeja P</searchLink>; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Banks+AS%22">Banks AS</searchLink>; Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Rosen+ED%22">Rosen ED</searchLink>; Division of Endocrinology, Beth Israel Deaconess Medical Center and Department of Genetics, Harvard Medical School, Boston, MA 02215, USA.<br /><searchLink fieldCode="AU" term="%22Spiegelman+BM%22">Spiegelman BM</searchLink>; Dana-Farber Cancer Institute, Boston, MA 02115, USA; Department of Cell Biology, Harvard University Medical School, Boston, MA 02115, USA. Electronic address: bruce_spiegelman@dfci.harvard.edu.
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              Text: 2017 Oct 03
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