View in EDS HTML Full Text PDF Full Text

Screening drug effects in patient-derived cancer cells links organoid responses to genome alterations.

Saved in:
Bibliographic Details
Title: Screening drug effects in patient-derived cancer cells links organoid responses to genome alterations.
Authors: Jabs J; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), University of Heidelberg, Heidelberg, Germany.; Department for Bioinformatics and Functional Genomics, Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant, Heidelberg University, Heidelberg, Germany., Zickgraf FM; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM) gGmbH, Heidelberg, Germany.; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Park J; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department for Bioinformatics and Functional Genomics, Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant, Heidelberg University, Heidelberg, Germany., Wagner S; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM) gGmbH, Heidelberg, Germany.; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Jiang X; Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany., Jechow K; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), University of Heidelberg, Heidelberg, Germany., Kleinheinz K; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), University of Heidelberg, Heidelberg, Germany.; Department for Bioinformatics and Functional Genomics, Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant, Heidelberg University, Heidelberg, Germany., Toprak UH; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany., Schneider MA; Thoraxklinik at Heidelberg University Hospital, Member of the German Center for Lung Research (DZL), Heidelberg, Germany., Meister M; Thoraxklinik at Heidelberg University Hospital, Member of the German Center for Lung Research (DZL), Heidelberg, Germany., Spaich S; Department of Gynaecology and Obstetrics, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany., Sütterlin M; Department of Gynaecology and Obstetrics, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany., Schlesner M; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany., Trumpp A; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM) gGmbH, Heidelberg, Germany.; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Cancer Consortium, Heidelberg, Germany., Sprick M; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM) gGmbH, Heidelberg, Germany.; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Cancer Consortium, Heidelberg, Germany., Eils R; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany r.eils@dkfz.de c.conrad@dkfz.de.; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), University of Heidelberg, Heidelberg, Germany.; Department for Bioinformatics and Functional Genomics, Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant, Heidelberg University, Heidelberg, Germany.; Heidelberg Center for Personalized Oncology, DKFZ-HIPO, DKFZ, Heidelberg, Germany., Conrad C; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany r.eils@dkfz.de c.conrad@dkfz.de.; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), University of Heidelberg, Heidelberg, Germany.
Source: Molecular systems biology [Mol Syst Biol] 2017 Nov 27; Vol. 13 (11), pp. 955. Date of Electronic Publication: 2017 Nov 27.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101235389 Publication Model: Electronic Cited Medium: Internet ISSN: 1744-4292 (Electronic) Linking ISSN: 17444292 NLM ISO Abbreviation: Mol Syst Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 29180611
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Screening drug effects in patient-derived cancer cells links organoid responses to genome alterations.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Jabs+J%22">Jabs J</searchLink>; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), University of Heidelberg, Heidelberg, Germany.; Department for Bioinformatics and Functional Genomics, Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant, Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Zickgraf+FM%22">Zickgraf FM</searchLink>; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM) gGmbH, Heidelberg, Germany.; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Park+J%22">Park J</searchLink>; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department for Bioinformatics and Functional Genomics, Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant, Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Wagner+S%22">Wagner S</searchLink>; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM) gGmbH, Heidelberg, Germany.; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Jiang+X%22">Jiang X</searchLink>; Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Jechow+K%22">Jechow K</searchLink>; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Kleinheinz+K%22">Kleinheinz K</searchLink>; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), University of Heidelberg, Heidelberg, Germany.; Department for Bioinformatics and Functional Genomics, Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant, Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Toprak+UH%22">Toprak UH</searchLink>; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Schneider+MA%22">Schneider MA</searchLink>; Thoraxklinik at Heidelberg University Hospital, Member of the German Center for Lung Research (DZL), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Meister+M%22">Meister M</searchLink>; Thoraxklinik at Heidelberg University Hospital, Member of the German Center for Lung Research (DZL), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Spaich+S%22">Spaich S</searchLink>; Department of Gynaecology and Obstetrics, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Sütterlin+M%22">Sütterlin M</searchLink>; Department of Gynaecology and Obstetrics, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Schlesner+M%22">Schlesner M</searchLink>; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Trumpp+A%22">Trumpp A</searchLink>; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM) gGmbH, Heidelberg, Germany.; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Cancer Consortium, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Sprick+M%22">Sprick M</searchLink>; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM) gGmbH, Heidelberg, Germany.; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Cancer Consortium, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Eils+R%22">Eils R</searchLink>; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany r.eils@dkfz.de c.conrad@dkfz.de.; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), University of Heidelberg, Heidelberg, Germany.; Department for Bioinformatics and Functional Genomics, Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant, Heidelberg University, Heidelberg, Germany.; Heidelberg Center for Personalized Oncology, DKFZ-HIPO, DKFZ, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Conrad+C%22">Conrad C</searchLink>; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany r.eils@dkfz.de c.conrad@dkfz.de.; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), University of Heidelberg, Heidelberg, Germany.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101235389%22">Molecular systems biology</searchLink> [Mol Syst Biol] 2017 Nov 27; Vol. 13 (11), pp. 955. <i>Date of Electronic Publication: </i>2017 Nov 27.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22EMBO+Press%22">EMBO Press </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101235389 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1744-4292 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217444292%22">17444292 </searchLink><i>NLM ISO Abbreviation: </i>Mol Syst Biol <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=29180611
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.15252/msb.20177697
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 955
    Titles:
      – TitleFull: Screening drug effects in patient-derived cancer cells links organoid responses to genome alterations.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Jabs J
      – PersonEntity:
          Name:
            NameFull: Zickgraf FM
      – PersonEntity:
          Name:
            NameFull: Park J
      – PersonEntity:
          Name:
            NameFull: Wagner S
      – PersonEntity:
          Name:
            NameFull: Jiang X
      – PersonEntity:
          Name:
            NameFull: Jechow K
      – PersonEntity:
          Name:
            NameFull: Kleinheinz K
      – PersonEntity:
          Name:
            NameFull: Toprak UH
      – PersonEntity:
          Name:
            NameFull: Schneider MA
      – PersonEntity:
          Name:
            NameFull: Meister M
      – PersonEntity:
          Name:
            NameFull: Spaich S
      – PersonEntity:
          Name:
            NameFull: Sütterlin M
      – PersonEntity:
          Name:
            NameFull: Schlesner M
      – PersonEntity:
          Name:
            NameFull: Trumpp A
      – PersonEntity:
          Name:
            NameFull: Sprick M
      – PersonEntity:
          Name:
            NameFull: Eils R
      – PersonEntity:
          Name:
            NameFull: Conrad C
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 27
              M: 11
              Text: 2017 Nov 27
              Type: published
              Y: 2017
          Identifiers:
            – Type: issn-electronic
              Value: 1744-4292
          Numbering:
            – Type: volume
              Value: 13
            – Type: issue
              Value: 11
          Titles:
            – TitleFull: Molecular systems biology
              Type: main
ResultId 1