Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism.

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Title: Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism.
Authors: Bilanges B; UCL Cancer Institute, University College London, 72 Huntley Street, London, WC1E 6DD, UK. b.bilanges@ucl.ac.uk., Alliouachene S; UCL Cancer Institute, University College London, 72 Huntley Street, London, WC1E 6DD, UK., Pearce W; UCL Cancer Institute, University College London, 72 Huntley Street, London, WC1E 6DD, UK., Morelli D; UCL Cancer Institute, University College London, 72 Huntley Street, London, WC1E 6DD, UK., Szabadkai G; Department of Cell and Developmental Biology, Consortium for Mitochondrial Research, University College London, Gower Street, London, WC1E 6BT, UK.; Department of Biomedical Sciences, University of Padua, Padua, 58/B via Ugo, Bassi, 35121, Italy., Chung YL; Cancer Research UK Cancer Imaging Centre, Division of Radiotherapy and Imaging, The Institute of Cancer Research London, 123 Old Brompton Road, London, SW7 3RP, UK., Chicanne G; Inserm/UPS UMR 1048, Institut des Maladies Métaboliques et Cardiovasculaires, 1 Avenue Jean Poulhès BP 84225, 31432, Toulouse Cedex 4, France., Valet C; Inserm/UPS UMR 1048, Institut des Maladies Métaboliques et Cardiovasculaires, 1 Avenue Jean Poulhès BP 84225, 31432, Toulouse Cedex 4, France., Hill JM; Department of Cell and Developmental Biology, Consortium for Mitochondrial Research, University College London, Gower Street, London, WC1E 6BT, UK., Voshol PJ; Metabolic Research Laboratories, MRC Metabolic Diseases Unit, Wellcome Trust-MRC Institute of Metabolic Science, Level 4, Box 289, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK., Collinson L; The Francis Crick Institute, Lincoln's Inn Fields Laboratories, 44 Lincoln's Inn Fields, London, WC2A 3LY, UK., Peddie C; The Francis Crick Institute, Lincoln's Inn Fields Laboratories, 44 Lincoln's Inn Fields, London, WC2A 3LY, UK., Ali K; UCL Cancer Institute, University College London, 72 Huntley Street, London, WC1E 6DD, UK., Ghazaly E; Centre of Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, EC1M 6BQ, UK., Rajeeve V; Centre of Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, EC1M 6BQ, UK., Trichas G; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, OX1 3PT, UK., Srinivas S; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, OX1 3PT, UK., Chaussade C; UCL Cancer Institute, University College London, 72 Huntley Street, London, WC1E 6DD, UK., Salamon RS; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, 10461, NY, USA., Backer JM; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, 10461, NY, USA., Scudamore CL; Mary Lyon Centre, MRC Harwell, Harwell Science and Innovation Campus, Harwell, OX11 0RD, UK., Whitehead MA; UCL Cancer Institute, University College London, 72 Huntley Street, London, WC1E 6DD, UK., Keaney EP; Novartis Institutes for BioMedical Research, 181 Massachusetts Avenue, Cambridge, MA, 02139, USA., Murphy LO; Novartis Institutes for BioMedical Research, 181 Massachusetts Avenue, Cambridge, MA, 02139, USA., Semple RK; Institute of Metabolic Science, University of Cambridge, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK., Payrastre B; Inserm/UPS UMR 1048, Institut des Maladies Métaboliques et Cardiovasculaires, 1 Avenue Jean Poulhès BP 84225, 31432, Toulouse Cedex 4, France., Tooze SA; The Francis Crick Institute, Lincoln's Inn Fields Laboratories, 44 Lincoln's Inn Fields, London, WC2A 3LY, UK., Vanhaesebroeck B; UCL Cancer Institute, University College London, 72 Huntley Street, London, WC1E 6DD, UK. bart.vanh@ucl.ac.uk.
Source: Nature communications [Nat Commun] 2017 Nov 27; Vol. 8 (1), pp. 1804. Date of Electronic Publication: 2017 Nov 27.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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