Advantages with prophylactic PEG-rhG-CSF versus rhG-CSF in breast cancer patients receiving multiple cycles of myelosuppressive chemotherapy: an open-label, randomized, multicenter phase III study.

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Title: Advantages with prophylactic PEG-rhG-CSF versus rhG-CSF in breast cancer patients receiving multiple cycles of myelosuppressive chemotherapy: an open-label, randomized, multicenter phase III study.
Authors: Xie J; Department of Medical Oncology, Fudan University Shanghai Cancer Center, 270 Dong'an Road, Shanghai, 200032, China.; Department of Oncology, Shanghai Medical College, Fudan University, 130 Dong'an Road, Shanghai, 200032, China., Cao J; Department of Medical Oncology, Fudan University Shanghai Cancer Center, 270 Dong'an Road, Shanghai, 200032, China.; Department of Oncology, Shanghai Medical College, Fudan University, 130 Dong'an Road, Shanghai, 200032, China., Wang JF; Linyi Tumor Hospital, Linyi, 276001, China., Zhang BH; Lanzhou Military General Hospital of People's Liberation Army, Gansu Lanzhou, 730050, China., Zeng XH; Chongqing Cancer Hospital, Chongqing, 400030, China., Zheng H; Chongqing Cancer Hospital, Chongqing, 400030, China., Zhang Y; Liaocheng People's Hospital, Liaocheng, 252000, China., Cai L; The Affiliated Tumor Hospital of Harbin Medical University, Harbin, 150081, China., Wu YD; Jiangxi Cancer Hospital, Nanchang, 330029, China., Yao Q; Tianjin People's Hospital, Tianjin, 300121, China., Zhao XC; The First Affiliated Hospital Of University Of South China, Hengyang, 421001, China., Mao WD; The Affiliated Jiangyin Hospital of Southeast University Medical College, Jiangyin, 214400, China., Jiang AM; First Affiliated Hospital of Kunming Medical University, Kunming, 650032, China., Chen SS; Binzhou Medical School Affiliated Hospital, Binzhou, 256603, China., Yang SE; Tumour Hospital Affiliated To Xinjiang Medical University, Urumqi, 830000, China., Wang SS; Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Wang JH; Nantong Tumor Hospital, Nantong, 226361, China., Pan YY; The First Affiliated Hospital Of Anhui Medical University, Hefei, 230022, China., Ren BY; Chongqing Three Gorges Central Hospital, Chongqing, 404000, China., Chen YJ; Hainan General Hospital, Haikou, 570311, China., Ouyang LZ; Hunan Cancer Hospital, Changsha, 410006, China., Lei KJ; The Second People's Hospital of Yibin, Yibin, 644000, China., Gao JH; Cangzhou Central Hospital, Cangzhou, 061001, China., Huang WH; Cancer Hospital of Shantou University Medical College, Shantou, 515000, China., Huang Z; Yue Bei People's Hospital, Shaoguan, 512025, China., Shou T; The First People's Hospital of Yunnan Province, Kunming, 650032, China., He YL; Peking University Shenzhen Hospital, Shenzhen, 518036, China., Cheng J; Huazhong University of Science and Technology Wuhan Union Hospital, Wuhan, 430022, China., Sun Y; People's Hospital of Sanya, Sanya, 572000, China., Li WM; The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China., Cui SD; Henan Cancer Hospital, Zhengzhou, 450008, China., Wang X; Zhongshan Hospital Affiliated To Xiamen University, Xiamen, 361004, China., Rao ZG; Wuhan General Hospital of Guangzhou Military, Wuhan, 430070, China., Ma H; Affiliated Hospital of Zunyi Medical College, Zunyi, 563000, China., Liu W; Affiliated Hospital of Beihua University, Jilin, 132011, China., Wu XY; Jing'an District Centre Hospital of Shanghai, Shanghai, 200040, China., Shen WX; Shenzhen People's Hospital, Shenzhen, 518020, China., Cao FL; Taizhou Hospital of Zhejiang Province, Taizhou, 317000, China., Xiao ZM; The First People's Hospital of Changde City, Changde, 415003, China., Wu B; The First Affiliated Hospital of Nanchang University, Nanchang, 330006, China., Tian SY; The Centre Hospital of Siping City, Siping, 136000, China., Meng D; Wu Xi No.4 People's Hospital, Wuxi, 214000, China., Shen P; The First Affiliated Hospital Of Zhejiang University, Hangzhou, 310003, China., Wang BY; Department of Medical Oncology, Fudan University Shanghai Cancer Center, 270 Dong'an Road, Shanghai, 200032, China.; Department of Oncology, Shanghai Medical College, Fudan University, 130 Dong'an Road, Shanghai, 200032, China., Wang Z; Department of Medical Oncology, Fudan University Shanghai Cancer Center, 270 Dong'an Road, Shanghai, 200032, China.; Department of Oncology, Shanghai Medical College, Fudan University, 130 Dong'an Road, Shanghai, 200032, China., Zhang J; Department of Medical Oncology, Fudan University Shanghai Cancer Center, 270 Dong'an Road, Shanghai, 200032, China.; Department of Oncology, Shanghai Medical College, Fudan University, 130 Dong'an Road, Shanghai, 200032, China., Wang L; Department of Medical Oncology, Fudan University Shanghai Cancer Center, 270 Dong'an Road, Shanghai, 200032, China.; Department of Oncology, Shanghai Medical College, Fudan University, 130 Dong'an Road, Shanghai, 200032, China., Hu XC; Department of Medical Oncology, Fudan University Shanghai Cancer Center, 270 Dong'an Road, Shanghai, 200032, China. xchu_fuscc@163.com.; Department of Oncology, Shanghai Medical College, Fudan University, 130 Dong'an Road, Shanghai, 200032, China. xchu_fuscc@163.com.
Source: Breast cancer research and treatment [Breast Cancer Res Treat] 2018 Apr; Vol. 168 (2), pp. 389-399. Date of Electronic Publication: 2017 Dec 11.
Publication Type: Clinical Trial, Phase III; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: Kluwer Academic Country of Publication: Netherlands NLM ID: 8111104 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7217 (Electronic) Linking ISSN: 01676806 NLM ISO Abbreviation: Breast Cancer Res Treat Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Advantages with prophylactic PEG-rhG-CSF versus rhG-CSF in breast cancer patients receiving multiple cycles of myelosuppressive chemotherapy: an open-label, randomized, multicenter phase III study.
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  Data: <searchLink fieldCode="AU" term="%22Xie+J%22">Xie J</searchLink>; Department of Medical Oncology, Fudan University Shanghai Cancer Center, 270 Dong'an Road, Shanghai, 200032, China.; Department of Oncology, Shanghai Medical College, Fudan University, 130 Dong'an Road, Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Cao+J%22">Cao J</searchLink>; Department of Medical Oncology, Fudan University Shanghai Cancer Center, 270 Dong'an Road, Shanghai, 200032, China.; Department of Oncology, Shanghai Medical College, Fudan University, 130 Dong'an Road, Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Wang+JF%22">Wang JF</searchLink>; Linyi Tumor Hospital, Linyi, 276001, China.<br /><searchLink fieldCode="AU" term="%22Zhang+BH%22">Zhang BH</searchLink>; Lanzhou Military General Hospital of People's Liberation Army, Gansu Lanzhou, 730050, China.<br /><searchLink fieldCode="AU" term="%22Zeng+XH%22">Zeng XH</searchLink>; Chongqing Cancer Hospital, Chongqing, 400030, China.<br /><searchLink fieldCode="AU" term="%22Zheng+H%22">Zheng H</searchLink>; Chongqing Cancer Hospital, Chongqing, 400030, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Liaocheng People's Hospital, Liaocheng, 252000, China.<br /><searchLink fieldCode="AU" term="%22Cai+L%22">Cai L</searchLink>; The Affiliated Tumor Hospital of Harbin Medical University, Harbin, 150081, China.<br /><searchLink fieldCode="AU" term="%22Wu+YD%22">Wu YD</searchLink>; Jiangxi Cancer Hospital, Nanchang, 330029, China.<br /><searchLink fieldCode="AU" term="%22Yao+Q%22">Yao Q</searchLink>; Tianjin People's Hospital, Tianjin, 300121, China.<br /><searchLink fieldCode="AU" term="%22Zhao+XC%22">Zhao XC</searchLink>; The First Affiliated Hospital Of University Of South China, Hengyang, 421001, China.<br /><searchLink fieldCode="AU" term="%22Mao+WD%22">Mao WD</searchLink>; The Affiliated Jiangyin Hospital of Southeast University Medical College, Jiangyin, 214400, China.<br /><searchLink fieldCode="AU" term="%22Jiang+AM%22">Jiang AM</searchLink>; First Affiliated Hospital of Kunming Medical University, Kunming, 650032, China.<br /><searchLink fieldCode="AU" term="%22Chen+SS%22">Chen SS</searchLink>; 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The Second People's Hospital of Yibin, Yibin, 644000, China.<br /><searchLink fieldCode="AU" term="%22Gao+JH%22">Gao JH</searchLink>; Cangzhou Central Hospital, Cangzhou, 061001, China.<br /><searchLink fieldCode="AU" term="%22Huang+WH%22">Huang WH</searchLink>; Cancer Hospital of Shantou University Medical College, Shantou, 515000, China.<br /><searchLink fieldCode="AU" term="%22Huang+Z%22">Huang Z</searchLink>; Yue Bei People's Hospital, Shaoguan, 512025, China.<br /><searchLink fieldCode="AU" term="%22Shou+T%22">Shou T</searchLink>; The First People's Hospital of Yunnan Province, Kunming, 650032, China.<br /><searchLink fieldCode="AU" term="%22He+YL%22">He YL</searchLink>; Peking University Shenzhen Hospital, Shenzhen, 518036, China.<br /><searchLink fieldCode="AU" term="%22Cheng+J%22">Cheng J</searchLink>; Huazhong University of Science and Technology Wuhan Union Hospital, Wuhan, 430022, China.<br /><searchLink fieldCode="AU" term="%22Sun+Y%22">Sun Y</searchLink>; People's Hospital of Sanya, Sanya, 572000, China.<br /><searchLink fieldCode="AU" term="%22Li+WM%22">Li WM</searchLink>; The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China.<br /><searchLink fieldCode="AU" term="%22Cui+SD%22">Cui SD</searchLink>; Henan Cancer Hospital, Zhengzhou, 450008, China.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Zhongshan Hospital Affiliated To Xiamen University, Xiamen, 361004, China.<br /><searchLink fieldCode="AU" term="%22Rao+ZG%22">Rao ZG</searchLink>; Wuhan General Hospital of Guangzhou Military, Wuhan, 430070, China.<br /><searchLink fieldCode="AU" term="%22Ma+H%22">Ma H</searchLink>; Affiliated Hospital of Zunyi Medical College, Zunyi, 563000, China.<br /><searchLink fieldCode="AU" term="%22Liu+W%22">Liu W</searchLink>; Affiliated Hospital of Beihua University, Jilin, 132011, China.<br /><searchLink fieldCode="AU" term="%22Wu+XY%22">Wu XY</searchLink>; Jing'an District Centre Hospital of Shanghai, Shanghai, 200040, China.<br /><searchLink fieldCode="AU" term="%22Shen+WX%22">Shen WX</searchLink>; Shenzhen People's Hospital, Shenzhen, 518020, China.<br /><searchLink fieldCode="AU" term="%22Cao+FL%22">Cao FL</searchLink>; 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Department of Medical Oncology, Fudan University Shanghai Cancer Center, 270 Dong'an Road, Shanghai, 200032, China.; Department of Oncology, Shanghai Medical College, Fudan University, 130 Dong'an Road, Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Department of Medical Oncology, Fudan University Shanghai Cancer Center, 270 Dong'an Road, Shanghai, 200032, China.; Department of Oncology, Shanghai Medical College, Fudan University, 130 Dong'an Road, Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Department of Medical Oncology, Fudan University Shanghai Cancer Center, 270 Dong'an Road, Shanghai, 200032, China.; Department of Oncology, Shanghai Medical College, Fudan University, 130 Dong'an Road, Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Hu+XC%22">Hu XC</searchLink>; Department of Medical Oncology, Fudan University Shanghai Cancer Center, 270 Dong'an Road, Shanghai, 200032, China. xchu_fuscc@163.com.; Department of Oncology, Shanghai Medical College, Fudan University, 130 Dong'an Road, Shanghai, 200032, China. xchu_fuscc@163.com.
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