Noncanonical agonist PPARγ ligands modulate the response to DNA damage and sensitize cancer cells to cytotoxic chemotherapy. - Khandekar MJ; Banks AS; Laznik-Bogoslavski D; White JP; Choi JH; Kazak L; Lo JC; Cohen P; Wong KK; Kamenecka TM; Griffin PR; Spiegelman BM (Proceedings of the National Academy of Sciences of the United States of America, 2018)