Epoxyazadiradione suppresses breast tumor growth through mitochondrial depolarization and caspase-dependent apoptosis by targeting PI3K/Akt pathway.
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| Title: | Epoxyazadiradione suppresses breast tumor growth through mitochondrial depolarization and caspase-dependent apoptosis by targeting PI3K/Akt pathway. |
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| Authors: | Kumar D; Laboratory of Tumor Biology, Angiogenesis and Nanomedicine Research, National Centre for Cell Science (NCCS), Pune, 411007, India., Haldar S; Chemical Biology Unit, Division of Organic Chemistry, CSIR-National Chemical Laboratory, Pune, 411008, India., Gorain M; Laboratory of Tumor Biology, Angiogenesis and Nanomedicine Research, National Centre for Cell Science (NCCS), Pune, 411007, India., Kumar S; Department of Biochemistry and Molecular and Cellular Biology, Georgetown University Medical Center, Washington D.C., 20057, USA., Mulani FA; Chemical Biology Unit, Division of Organic Chemistry, CSIR-National Chemical Laboratory, Pune, 411008, India., Yadav AS; Laboratory of Tumor Biology, Angiogenesis and Nanomedicine Research, National Centre for Cell Science (NCCS), Pune, 411007, India., Miele L; Department of Genetics, LSU Health Sciences Center, New Orleans, LA, 70112, USA., Thulasiram HV; Chemical Biology Unit, Division of Organic Chemistry, CSIR-National Chemical Laboratory, Pune, 411008, India., Kundu GC; Laboratory of Tumor Biology, Angiogenesis and Nanomedicine Research, National Centre for Cell Science (NCCS), Pune, 411007, India. kundu@nccs.res.in. |
| Source: | BMC cancer [BMC Cancer] 2018 Jan 08; Vol. 18 (1), pp. 52. Date of Electronic Publication: 2018 Jan 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1471-2407 |
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| DOI: | 10.1186/s12885-017-3876-2 |
