NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus.
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| Title: | NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus. |
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| Authors: | Brightbill HD; Department of Immunology Discovery, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Suto E; Department of Translational Immunology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Blaquiere N; Department of Discovery Chemistry, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Ramamoorthi N; Department of Biomarker Discovery, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Sujatha-Bhaskar S; Department of Immunology Discovery, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Gogol EB; Department of Immunology Discovery, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Castanedo GM; Department of Discovery Chemistry, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Jackson BT; Department of Immunology Discovery, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Kwon YC; Department of Translational Immunology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Haller S; Department of Pathology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Lesch J; Department of Translational Immunology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Bents K; Evotec, Inc., Essener Bogen 7, Hamburg, 22419, Germany., Everett C; Department of Biochemical and Cellular Pharmacology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Kohli PB; Department of Biochemical and Cellular Pharmacology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Linge S; Evotec, Inc., Essener Bogen 7, Hamburg, 22419, Germany., Christian L; Department of Immunology Discovery, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Barrett K; Department of Biochemical and Cellular Pharmacology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Jaochico A; Department of Drug Metabolism and Pharmacokinetics, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Berezhkovskiy LM; Department of Drug Metabolism and Pharmacokinetics, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Fan PW; Department of Drug Metabolism and Pharmacokinetics, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Modrusan Z; Department of Molecular Biology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Veliz K; Department of Laboratory Animal Resources, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Townsend MJ; Department of Biomarker Discovery, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., DeVoss J; Department of Translational Immunology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Johnson AR; Department of Biochemical and Cellular Pharmacology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Godemann R; Evotec, Inc., Essener Bogen 7, Hamburg, 22419, Germany., Lee WP; Department of Translational Immunology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Austin CD; Department of Pathology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., McKenzie BS; Department of Translational Immunology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Hackney JA; Department of Bioinformatics and Computational Biology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Crawford JJ; Department of Discovery Chemistry, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Staben ST; Department of Discovery Chemistry, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Alaoui Ismaili MH; Department of Biochemical and Cellular Pharmacology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Wu LC; Department of Immunology Discovery, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA., Ghilardi N; Department of Immunology Discovery, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA. ghilardi.nico@gene.com. |
| Source: | Nature communications [Nat Commun] 2018 Jan 12; Vol. 9 (1), pp. 179. Date of Electronic Publication: 2018 Jan 12. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 29330524 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Brightbill+HD%22">Brightbill HD</searchLink>; Department of Immunology Discovery, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Suto+E%22">Suto E</searchLink>; Department of Translational Immunology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Blaquiere+N%22">Blaquiere N</searchLink>; Department of Discovery Chemistry, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Ramamoorthi+N%22">Ramamoorthi N</searchLink>; Department of Biomarker Discovery, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Sujatha-Bhaskar+S%22">Sujatha-Bhaskar S</searchLink>; Department of Immunology Discovery, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Gogol+EB%22">Gogol EB</searchLink>; Department of Immunology Discovery, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Castanedo+GM%22">Castanedo GM</searchLink>; Department of Discovery Chemistry, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Jackson+BT%22">Jackson BT</searchLink>; Department of Immunology Discovery, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Kwon+YC%22">Kwon YC</searchLink>; Department of Translational Immunology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Haller+S%22">Haller S</searchLink>; Department of Pathology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Lesch+J%22">Lesch J</searchLink>; Department of Translational Immunology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Bents+K%22">Bents K</searchLink>; Evotec, Inc., Essener Bogen 7, Hamburg, 22419, Germany.<br /><searchLink fieldCode="AU" term="%22Everett+C%22">Everett C</searchLink>; Department of Biochemical and Cellular Pharmacology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Kohli+PB%22">Kohli PB</searchLink>; Department of Biochemical and Cellular Pharmacology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Linge+S%22">Linge S</searchLink>; Evotec, Inc., Essener Bogen 7, Hamburg, 22419, Germany.<br /><searchLink fieldCode="AU" term="%22Christian+L%22">Christian L</searchLink>; Department of Immunology Discovery, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Barrett+K%22">Barrett K</searchLink>; Department of Biochemical and Cellular Pharmacology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Jaochico+A%22">Jaochico A</searchLink>; Department of Drug Metabolism and Pharmacokinetics, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Berezhkovskiy+LM%22">Berezhkovskiy LM</searchLink>; Department of Drug Metabolism and Pharmacokinetics, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Fan+PW%22">Fan PW</searchLink>; Department of Drug Metabolism and Pharmacokinetics, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Modrusan+Z%22">Modrusan Z</searchLink>; Department of Molecular Biology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Veliz+K%22">Veliz K</searchLink>; Department of Laboratory Animal Resources, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Townsend+MJ%22">Townsend MJ</searchLink>; Department of Biomarker Discovery, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22DeVoss+J%22">DeVoss J</searchLink>; Department of Translational Immunology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+AR%22">Johnson AR</searchLink>; Department of Biochemical and Cellular Pharmacology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Godemann+R%22">Godemann R</searchLink>; Evotec, Inc., Essener Bogen 7, Hamburg, 22419, Germany.<br /><searchLink fieldCode="AU" term="%22Lee+WP%22">Lee WP</searchLink>; Department of Translational Immunology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Austin+CD%22">Austin CD</searchLink>; Department of Pathology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22McKenzie+BS%22">McKenzie BS</searchLink>; Department of Translational Immunology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Hackney+JA%22">Hackney JA</searchLink>; Department of Bioinformatics and Computational Biology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Crawford+JJ%22">Crawford JJ</searchLink>; Department of Discovery Chemistry, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Staben+ST%22">Staben ST</searchLink>; Department of Discovery Chemistry, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Alaoui+Ismaili+MH%22">Alaoui Ismaili MH</searchLink>; Department of Biochemical and Cellular Pharmacology, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Wu+LC%22">Wu LC</searchLink>; Department of Immunology Discovery, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA.<br /><searchLink fieldCode="AU" term="%22Ghilardi+N%22">Ghilardi N</searchLink>; Department of Immunology Discovery, Genentech, 1 DNA Way, South San Francisco, CA-94080, USA. ghilardi.nico@gene.com. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2018 Jan 12; Vol. 9 (1), pp. 179. <i>Date of Electronic Publication: </i>2018 Jan 12. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41467-017-02672-0 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 179 Titles: – TitleFull: NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Brightbill HD – PersonEntity: Name: NameFull: Suto E – PersonEntity: Name: NameFull: Blaquiere N – PersonEntity: Name: NameFull: Ramamoorthi N – PersonEntity: Name: NameFull: Sujatha-Bhaskar S – PersonEntity: Name: NameFull: Gogol EB – PersonEntity: Name: NameFull: Castanedo GM – PersonEntity: Name: NameFull: Jackson BT – PersonEntity: Name: NameFull: Kwon YC – PersonEntity: Name: NameFull: Haller S – PersonEntity: Name: NameFull: Lesch J – PersonEntity: Name: NameFull: Bents K – PersonEntity: Name: NameFull: Everett C – PersonEntity: Name: NameFull: Kohli PB – PersonEntity: Name: NameFull: Linge S – PersonEntity: Name: NameFull: Christian L – PersonEntity: Name: NameFull: Barrett K – PersonEntity: Name: NameFull: Jaochico A – PersonEntity: Name: NameFull: Berezhkovskiy LM – PersonEntity: Name: NameFull: Fan PW – PersonEntity: Name: NameFull: Modrusan Z – PersonEntity: Name: NameFull: Veliz K – PersonEntity: Name: NameFull: Townsend MJ – PersonEntity: Name: NameFull: DeVoss J – PersonEntity: Name: NameFull: Johnson AR – PersonEntity: Name: NameFull: Godemann R – PersonEntity: Name: NameFull: Lee WP – PersonEntity: Name: NameFull: Austin CD – PersonEntity: Name: NameFull: McKenzie BS – PersonEntity: Name: NameFull: Hackney JA – PersonEntity: Name: NameFull: Crawford JJ – PersonEntity: Name: NameFull: Staben ST – PersonEntity: Name: NameFull: Alaoui Ismaili MH – PersonEntity: Name: NameFull: Wu LC – PersonEntity: Name: NameFull: Ghilardi N IsPartOfRelationships: – BibEntity: Dates: – D: 12 M: 01 Text: 2018 Jan 12 Type: published Y: 2018 Identifiers: – Type: issn-electronic Value: 2041-1723 Numbering: – Type: volume Value: 9 – Type: issue Value: 1 Titles: – TitleFull: Nature communications Type: main |
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