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Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease.

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Title: Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease.
Authors: Baillie JK; Division of Genetics and Genomics, The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom.; Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom.; Intensive Care Unit, Royal Infirmary Edinburgh, Edinburgh, United Kingdom., Bretherick A; Division of Genetics and Genomics, The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom., Haley CS; Division of Genetics and Genomics, The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom.; Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom., Clohisey S; Division of Genetics and Genomics, The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom., Gray A; Edinburgh Parallel Computing Centre, The University of Edinburgh, Edinburgh, United Kingdom., Neyton LPA; Division of Genetics and Genomics, The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom., Barrett J; Statistical Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom., Stahl EA; Center for Statistical Genetics, Icahn School of Medicine at Mount Sinai, New York, United States of America., Tenesa A; Division of Genetics and Genomics, The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom., Andersson R; The Bioinformatics Centre, Department of Biology & Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark., Brown JB; Department of Statistics, University of California, Berkeley, United States of America., Faulkner GJ; Mater Research Institute, University of Queensland, University of Queensland, Brisbane, Australia., Lizio M; RIKEN Omics Science Center, Yokohama, Japan, Division of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Japan., Schaefer U; Department for Infectious Disease Informatics, Public Health England, Colindale, United Kingdom., Daub C; RIKEN Omics Science Center, Yokohama, Japan, Division of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Japan., Itoh M; RIKEN Omics Science Center, Yokohama, Japan, Division of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Japan.; RIKEN Preventive Medicine and Diagnosis Innovation Program, Wako, Japan., Kondo N; RIKEN Omics Science Center, Yokohama, Japan, Division of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Japan., Lassmann T; RIKEN Omics Science Center, Yokohama, Japan, Division of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Japan., Kawai J; RIKEN Omics Science Center, Yokohama, Japan, Division of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Japan., Mole D; Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom., Bajic VB; King Abdullah University of Science and Technology (KAUST), Computational Bioscience Research Center, Thuwal, Kingdom of Saudi Arabia., Heutink P; German Center for Neurodegenerative Diseases, Tübingen, Germany., Rehli M; Dept. Hematology, University Hospital Regensburg, Regensburg, Germany., Kawaji H; RIKEN Omics Science Center, Yokohama, Japan, Division of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Japan.; RIKEN Preventive Medicine and Diagnosis Innovation Program, Wako, Japan., Sandelin A; The Bioinformatics Centre, Department of Biology & Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark., Suzuki H; RIKEN Omics Science Center, Yokohama, Japan, Division of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Japan., Satsangi J; Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom., Wells CA; Australian Institute for Bioengineering and Nanotechnology, University of Queensland, St Lucia, Brisbane Australia., Hacohen N; Broad Institute of Harvard and MIT, Cambridge, United States of America., Freeman TC; Division of Genetics and Genomics, The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom., Hayashizaki Y; RIKEN Omics Science Center, Yokohama, Japan, Division of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Japan., Carninci P; RIKEN Omics Science Center, Yokohama, Japan, Division of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Japan., Forrest ARR; Harry Perkins Institute of Medical Research, and the Centre for Medical Research, University of Western Australia, QEII Medical Centre, Nedlands, Perth, Western Australia, Australia., Hume DA; Division of Genetics and Genomics, The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom.; Mater Research Institute, University of Queensland, University of Queensland, Brisbane, Australia.
Corporate Authors: IIBDGC Consortium
Source: PLoS computational biology [PLoS Comput Biol] 2018 Mar 01; Vol. 14 (3), pp. e1005934. Date of Electronic Publication: 2018 Mar 01 (Print Publication: 2018).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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