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Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score.

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Title: Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score.
Authors: Carbone M; Academic Department of Medical Genetics, University of Cambridge, Cambridge, UK; Division of Gastroenterology and Hepatology, Department of Medicine and Surgery, University of Milan Bicocca, Milan, Italy. Electronic address: marco.carbone@unimib.it., Nardi A; Department of Mathematics, University of Rome Tor Vergata, Rome, Italy., Flack S; Academic Department of Medical Genetics, University of Cambridge, Cambridge, UK., Carpino G; Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', Rome, Italy., Varvaropoulou N; Academic Department of Medical Genetics, University of Cambridge, Cambridge, UK., Gavrila C; IC Antonio Rosmini, Rome, Italy., Spicer A; Academic Department of Medical Genetics, University of Cambridge, Cambridge, UK., Badrock J; Academic Department of Medical Genetics, University of Cambridge, Cambridge, UK., Bernuzzi F; Division of Gastroenterology and Hepatology, Department of Medicine and Surgery, University of Milan Bicocca, Milan, Italy., Cardinale V; Department of Medico-Surgical Sciences and Biotechnologies, Polo Pontino, Sapienza University of Rome, Rome, Italy., Ainsworth HF; Institute of Health & Society, Newcastle University, Newcastle-upon-Tyne, UK., Heneghan MA; Institute of Liver Studies, King's College Hospital NHS Foundation Trust, London, UK., Thorburn D; Sheila Sherlock Liver Centre, The Royal Free London NHS Foundation Trust, London, UK., Bathgate A; Scottish Liver Transplant Unit, Royal Infirmary of Edinburgh, Edinburgh, UK., Jones R; Liver Unit, St James's University Hospital, Leeds, UK., Neuberger JM; Liver Unit, Queen Elizabeth Hospital, Birmingham, UK., Battezzati PM; Division of Internal Medicine and Liver Unit, Ospedale San Paolo, Milan, Italy., Zuin M; Division of Internal Medicine and Liver Unit, Ospedale San Paolo, Milan, Italy., Taylor-Robinson S; Liver Unit, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, UK., Donato MF; CRC 'AM e A Migliavacca' Center for the Study of Liver Disease, Division of Gastroenterology and Hepatology, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, Milan, Italy., Kirby J; Applied Immunobiology and Transplantation Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle-upon-Tyne, UK., Mitchell-Thain R; PBC Foundation, Edinburgh, UK., Floreani A; Department of Surgery, Oncology and Gastroenterology, University of Padova, Padua, Italy., Sampaziotis F; Department of Surgery, Wellcome Trust-Medical Research Council Stem Cell Institute, Anne McLaren Laboratory, University of Cambridge, Cambridge, UK., Muratori L; Liver Unit, Policlinico di Sant'Orsola-Malpighi, Bologna, Italy., Alvaro D; Department of Medico-Surgical Sciences and Biotechnologies, Polo Pontino, Sapienza University of Rome, Rome, Italy., Marzioni M; Division of Gastroenterology and Hepatology, Ospedali Riuniti University Hospital, Ancona, Italy., Miele L; Department of Internal Medicine and Gastroenterology, Gemelli University Hospital, Rome, Italy., Marra F; Department of Clinical and Experimental Medicine, University of Florence, Florence, Italy., Giannini E; Division of Gastroenterology, Department of Internal Medicine, IRCCS-Azienda Ospedaliera Universitaria San Martino-IST, Genoa, Italy., Gaudio E; Department of Anatomy, Histology, Legal Medicine, and Orthopedics, Sapienza University of Rome, Rome, Italy., Ronca V; Division of Internal Medicine and Liver Unit, Ospedale San Paolo, Milan, Italy., Bonato G; Division of Gastroenterology and Hepatology, Department of Medicine and Surgery, University of Milan Bicocca, Milan, Italy., Cristoferi L; Division of Gastroenterology and Hepatology, Department of Medicine and Surgery, University of Milan Bicocca, Milan, Italy., Malinverno F; Division of Gastroenterology and Hepatology, Department of Medicine and Surgery, University of Milan Bicocca, Milan, Italy., Gerussi A; Division of Gastroenterology and Hepatology, Department of Medicine and Surgery, University of Milan Bicocca, Milan, Italy., Stocken DD; Institute of Health & Society, Newcastle University, Newcastle-upon-Tyne, UK., Cordell HJ; Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, UK., Hirschfield GM; NIHR Birmingham Biomedical Research Centre, University of Birmingham, Birmingham, UK; University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Alexander GJ; Department of Medicine, University of Cambridge, Cambridge, UK., Sandford RN; Academic Department of Medical Genetics, University of Cambridge, Cambridge, UK., Jones DE; Institute of Cellular Medicine, Newcastle University, Newcastle-upon-Tyne, UK., Invernizzi P; Division of Gastroenterology and Hepatology, Department of Medicine and Surgery, University of Milan Bicocca, Milan, Italy., Mells GF; Academic Department of Medical Genetics, University of Cambridge, Cambridge, UK.
Corporate Authors: Italian PBC Study Group and the UK–PBC Consortium
Source: The lancet. Gastroenterology & hepatology [Lancet Gastroenterol Hepatol] 2018 Sep; Vol. 3 (9), pp. 626-634. Date of Electronic Publication: 2018 Jul 13.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Validation Study
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101690683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2468-1253 (Electronic) NLM ISO Abbreviation: Lancet Gastroenterol Hepatol Subsets: MEDLINE
Database: MEDLINE Ultimate
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