Hyperactivated PI3Kδ promotes self and commensal reactivity at the expense of optimal humoral immunity.
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| Title: | Hyperactivated PI3Kδ promotes self and commensal reactivity at the expense of optimal humoral immunity. |
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| Authors: | Preite S; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA. silvia.preite@nih.gov.; Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. silvia.preite@nih.gov., Cannons JL; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.; Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Radtke AJ; Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Vujkovic-Cvijin I; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Gomez-Rodriguez J; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.; Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Volpi S; Clinica Pediatrica e Reumatologia, Centro per le Malattie Autoinfiammatorie e Immunodeficienze, Istituto Giannina Gaslini, Genoa, Italy.; Università degli Studi di Genova, Genoa, Italy., Huang B; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.; Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Cheng J; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Collins N; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Reilley J; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.; Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Handon R; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Dobbs K; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Huq L; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Raman I; Microarray Core Facility, University of Texas Southwestern Medical Center, Dallas, TX, USA., Zhu C; Microarray Core Facility, University of Texas Southwestern Medical Center, Dallas, TX, USA., Li QZ; Microarray Core Facility, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Department of Immunology, University of Texas Southwestern Medical Center, Dallas, TX, USA., Li MO; Immunology Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA., Pittaluga S; Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Uzel G; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Notarangelo LD; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Belkaid Y; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.; Microbiome Program, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Germain RN; Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Schwartzberg PL; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA. pams@mail.nih.gov.; Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. pams@mail.nih.gov. |
| Source: | Nature immunology [Nat Immunol] 2018 Sep; Vol. 19 (9), pp. 986-1000. Date of Electronic Publication: 2018 Aug 20. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural |
| Journal Info: | Publisher: Nature America Inc Country of Publication: United States NLM ID: 100941354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2916 (Electronic) Linking ISSN: 15292908 NLM ISO Abbreviation: Nat Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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