Vectored delivery of anti-SIV envelope targeting mAb via AAV8 protects rhesus macaques from repeated limiting dose intrarectal swarm SIVsmE660 challenge.
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| Title: | Vectored delivery of anti-SIV envelope targeting mAb via AAV8 protects rhesus macaques from repeated limiting dose intrarectal swarm SIVsmE660 challenge. |
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| Authors: | Welles HC; Immunotechnology Section, Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.; Institute for Biomedical Sciences, The George Washington University, Washington, DC, United States of America., Jennewein MF; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America., Mason RD; Immunotechnology Section, Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America., Narpala S; Immunotechnology Section, Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America., Wang L; Immunotechnology Section, Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America., Cheng C; Immunotechnology Section, Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America., Zhang Y; Immunotechnology Section, Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America., Todd JP; Immunotechnology Section, Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America., Lifson JD; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory of Cancer Research, Frederick, Maryland, United States of America., Balazs AB; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America., Alter G; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America., McDermott AB; Immunotechnology Section, Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America., Mascola JR; Immunotechnology Section, Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America., Roederer M; Immunotechnology Section, Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America. |
| Source: | PLoS pathogens [PLoS Pathog] 2018 Dec 05; Vol. 14 (12), pp. e1007395. Date of Electronic Publication: 2018 Dec 05 (Print Publication: 2018). |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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