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Machine learning applied to enzyme turnover numbers reveals protein structural correlates and improves metabolic models.

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Title: Machine learning applied to enzyme turnover numbers reveals protein structural correlates and improves metabolic models.
Authors: Heckmann D; Department of Bioengineering, University of California, San Diego, La Jolla, CA, 92093-0412, USA. dheckmann@ucsd.edu., Lloyd CJ; Department of Bioengineering, University of California, San Diego, La Jolla, CA, 92093-0412, USA., Mih N; Department of Bioengineering, University of California, San Diego, La Jolla, CA, 92093-0412, USA., Ha Y; Department of Bioengineering, University of California, San Diego, La Jolla, CA, 92093-0412, USA., Zielinski DC; Department of Bioengineering, University of California, San Diego, La Jolla, CA, 92093-0412, USA., Haiman ZB; Department of Bioengineering, University of California, San Diego, La Jolla, CA, 92093-0412, USA., Desouki AA; Institute for Computer Science and Department of Biology, Heinrich Heine University, 40225, Düsseldorf, Germany., Lercher MJ; Institute for Computer Science and Department of Biology, Heinrich Heine University, 40225, Düsseldorf, Germany., Palsson BO; Department of Bioengineering, University of California, San Diego, La Jolla, CA, 92093-0412, USA. palsson@ucsd.edu.; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, 2800, Lyngby, Denmark. palsson@ucsd.edu.
Source: Nature communications [Nat Commun] 2018 Dec 07; Vol. 9 (1), pp. 5252. Date of Electronic Publication: 2018 Dec 07.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Heckmann+D%22">Heckmann D</searchLink>; Department of Bioengineering, University of California, San Diego, La Jolla, CA, 92093-0412, USA. dheckmann@ucsd.edu.<br /><searchLink fieldCode="AU" term="%22Lloyd+CJ%22">Lloyd CJ</searchLink>; Department of Bioengineering, University of California, San Diego, La Jolla, CA, 92093-0412, USA.<br /><searchLink fieldCode="AU" term="%22Mih+N%22">Mih N</searchLink>; Department of Bioengineering, University of California, San Diego, La Jolla, CA, 92093-0412, USA.<br /><searchLink fieldCode="AU" term="%22Ha+Y%22">Ha Y</searchLink>; Department of Bioengineering, University of California, San Diego, La Jolla, CA, 92093-0412, USA.<br /><searchLink fieldCode="AU" term="%22Zielinski+DC%22">Zielinski DC</searchLink>; Department of Bioengineering, University of California, San Diego, La Jolla, CA, 92093-0412, USA.<br /><searchLink fieldCode="AU" term="%22Haiman+ZB%22">Haiman ZB</searchLink>; Department of Bioengineering, University of California, San Diego, La Jolla, CA, 92093-0412, USA.<br /><searchLink fieldCode="AU" term="%22Desouki+AA%22">Desouki AA</searchLink>; Institute for Computer Science and Department of Biology, Heinrich Heine University, 40225, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Lercher+MJ%22">Lercher MJ</searchLink>; Institute for Computer Science and Department of Biology, Heinrich Heine University, 40225, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Palsson+BO%22">Palsson BO</searchLink>; Department of Bioengineering, University of California, San Diego, La Jolla, CA, 92093-0412, USA. palsson@ucsd.edu.; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, 2800, Lyngby, Denmark. palsson@ucsd.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2018 Dec 07; Vol. 9 (1), pp. 5252. <i>Date of Electronic Publication: </i>2018 Dec 07.
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