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Probing the Virtual Proteome to Identify Novel Disease Biomarkers.

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Title: Probing the Virtual Proteome to Identify Novel Disease Biomarkers.
Authors: Mosley JD; Department of Medicine (J.D.M., C.M.S., J.F.F., J.C.D., T.J.W.), Vanderbilt University Medical Center, Nashville, TN., Benson MD; Cardiovascular Division, Brigham and Women's Hospital, Boston, MA (M.D.B.).; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA (M.D.B., M.S.H., R.E.G.)., Smith JG; Molecular Epidemiology and Cardiology, Clinical Sciences, Lund University and Skåne University Hospital, Malmö, Sweden (J.G.S., O.M.)., Melander O; Molecular Epidemiology and Cardiology, Clinical Sciences, Lund University and Skåne University Hospital, Malmö, Sweden (J.G.S., O.M.)., Ngo D; Department of Medicine and the Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston (D.N.)., Shaffer CM; Department of Medicine (J.D.M., C.M.S., J.F.F., J.C.D., T.J.W.), Vanderbilt University Medical Center, Nashville, TN., Ferguson JF; Department of Medicine (J.D.M., C.M.S., J.F.F., J.C.D., T.J.W.), Vanderbilt University Medical Center, Nashville, TN., Herzig MS; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA (M.D.B., M.S.H., R.E.G.)., McCarty CA; University of Minnesota Medical School, Duluth Campus (C.A.M.)., Chute CG; Schools of Medicine, Public Health, and Nursing, Johns Hopkins University, Baltimore, MD (C.G.C.)., Jarvik GP; Departments of Medicine (J.P.J., A.S.G., M.R.P., E.B.L.), University of Washington, Seattle., Gordon AS; Departments of Medicine (J.P.J., A.S.G., M.R.P., E.B.L.), University of Washington, Seattle., Palmer MR; Departments of Medicine (J.P.J., A.S.G., M.R.P., E.B.L.), University of Washington, Seattle., Crosslin DR; Biomedical Informatics and Medical Education (D.R.C.), University of Washington, Seattle., Larson EB; Departments of Medicine (J.P.J., A.S.G., M.R.P., E.B.L.), University of Washington, Seattle.; Kaiser Permanente Washington Health Research Institute, Seattle, WA (E.B.L., D.S.C.)., Carrell DS; Kaiser Permanente Washington Health Research Institute, Seattle, WA (E.B.L., D.S.C.)., Kullo IJ; Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN (I.J.K.)., Pacheco JA; Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (J.A.P.)., Peissig PL; Biomedical Informatics Research Center (P.L.P., J.G.L.), Marshfield Clinic Research Institute, WI., Brilliant MH; Center for Computational and Biomedical Informatics (M.H.B., T.E.K.), Marshfield Clinic Research Institute, WI., Kitchner TE; Center for Computational and Biomedical Informatics (M.H.B., T.E.K.), Marshfield Clinic Research Institute, WI., Linneman JG; Biomedical Informatics Research Center (P.L.P., J.G.L.), Marshfield Clinic Research Institute, WI., Namjou B; Cincinnati Children's Hospital Medical Center and University of Cincinnati, OH (B.N.)., Williams MS; Genomic Medicine Institute (M.S.W.), Geisinger Health System, Danville, PA., Ritchie MD; Departments of Bioinformatics and Genetics (M.D.R.), University of Pennsylvania, Philadelphia., Borthwick KM; Biomedical and Translational Informatics (K.M.B.), Geisinger Health System, Danville, PA., Kiryluk K; Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY (K.K.)., Mentch FD; Center for Applied Genomics, Children's Hospital of Philadelphia, PA (F.D.M., P.M.S.)., Sleiman PM; Center for Applied Genomics, Children's Hospital of Philadelphia, PA (F.D.M., P.M.S.)., Karlson EW; Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (E.W.K.)., Verma SS; Perelman School of Medicine, Department of Genetics (S.S.V.), University of Pennsylvania, Philadelphia., Zhu Y; Department of Biostatistics, Boston University School of Public Health, MA (Y.Z., Q.Y.)., Vasan RS; Department of Medicine, Boston University School of Medicine, MA (R.S.V.)., Yang Q; Department of Biostatistics, Boston University School of Public Health, MA (Y.Z., Q.Y.)., Denny JC; Department of Medicine (J.D.M., C.M.S., J.F.F., J.C.D., T.J.W.), Vanderbilt University Medical Center, Nashville, TN.; Biomedical Informatics (J.C.D., D.M.R.), Vanderbilt University Medical Center, Nashville, TN., Roden DM; Biomedical Informatics (J.C.D., D.M.R.), Vanderbilt University Medical Center, Nashville, TN.; Department of Pharmacology (D.M.R.), Vanderbilt University Medical Center, Nashville, TN., Gerszten RE; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA (M.D.B., M.S.H., R.E.G.)., Wang TJ; Department of Medicine (J.D.M., C.M.S., J.F.F., J.C.D., T.J.W.), Vanderbilt University Medical Center, Nashville, TN.
Source: Circulation [Circulation] 2018 Nov 27; Vol. 138 (22), pp. 2469-2481.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0147763 Publication Model: Print Cited Medium: Internet ISSN: 1524-4539 (Electronic) Linking ISSN: 00097322 NLM ISO Abbreviation: Circulation Subsets: MEDLINE
Database: MEDLINE Ultimate
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