Design of Novel Inhibitors of Human Thymidine Phosphorylase: Synthesis, Enzyme Inhibition, in Vitro Toxicity, and Impact on Human Glioblastoma Cancer.
Saved in:
| Title: | Design of Novel Inhibitors of Human Thymidine Phosphorylase: Synthesis, Enzyme Inhibition, in Vitro Toxicity, and Impact on Human Glioblastoma Cancer. |
|---|---|
| Authors: | de Moura Sperotto ND, Deves Roth C, Rodrigues-Junior VS, Ev Neves C, Reisdorfer Paula F; Laboratório de Desenvolvimento e Controle de Qualidade em Medicamentos , Universidade Federal do Pampa , 97508-000 Uruguaiana , RS , Brazil., da Silva Dadda A, Bergo P, Freitas de Freitas T, Souza Macchi F, Moura S; Laboratório de Produtos Naturais e Sintéticos, Instituto de Biotecnologia , Universidade de Caxias do Sul , 95070-560 Caxias do Sul , RS , Brazil., Duarte de Souza AP, Campos MM, Valim Bizarro C, Santos DS, Basso LA, Machado P |
| Source: | Journal of medicinal chemistry [J Med Chem] 2019 Feb 14; Vol. 62 (3), pp. 1231-1245. Date of Electronic Publication: 2019 Jan 17. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 30615449 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Design of Novel Inhibitors of Human Thymidine Phosphorylase: Synthesis, Enzyme Inhibition, in Vitro Toxicity, and Impact on Human Glioblastoma Cancer. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22de+Moura+Sperotto+ND%22">de Moura Sperotto ND</searchLink><br /><searchLink fieldCode="AU" term="%22Deves+Roth+C%22">Deves Roth C</searchLink><br /><searchLink fieldCode="AU" term="%22Rodrigues-Junior+VS%22">Rodrigues-Junior VS</searchLink><br /><searchLink fieldCode="AU" term="%22Ev+Neves+C%22">Ev Neves C</searchLink><br /><searchLink fieldCode="AU" term="%22Reisdorfer+Paula+F%22">Reisdorfer Paula F</searchLink>; Laboratório de Desenvolvimento e Controle de Qualidade em Medicamentos , Universidade Federal do Pampa , 97508-000 Uruguaiana , RS , Brazil.<br /><searchLink fieldCode="AU" term="%22da+Silva+Dadda+A%22">da Silva Dadda A</searchLink><br /><searchLink fieldCode="AU" term="%22Bergo+P%22">Bergo P</searchLink><br /><searchLink fieldCode="AU" term="%22Freitas+de+Freitas+T%22">Freitas de Freitas T</searchLink><br /><searchLink fieldCode="AU" term="%22Souza+Macchi+F%22">Souza Macchi F</searchLink><br /><searchLink fieldCode="AU" term="%22Moura+S%22">Moura S</searchLink>; Laboratório de Produtos Naturais e Sintéticos, Instituto de Biotecnologia , Universidade de Caxias do Sul , 95070-560 Caxias do Sul , RS , Brazil.<br /><searchLink fieldCode="AU" term="%22Duarte+de+Souza+AP%22">Duarte de Souza AP</searchLink><br /><searchLink fieldCode="AU" term="%22Campos+MM%22">Campos MM</searchLink><br /><searchLink fieldCode="AU" term="%22Valim+Bizarro+C%22">Valim Bizarro C</searchLink><br /><searchLink fieldCode="AU" term="%22Santos+DS%22">Santos DS</searchLink><br /><searchLink fieldCode="AU" term="%22Basso+LA%22">Basso LA</searchLink><br /><searchLink fieldCode="AU" term="%22Machado+P%22">Machado P</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229716531%22">Journal of medicinal chemistry</searchLink> [J Med Chem] 2019 Feb 14; Vol. 62 (3), pp. 1231-1245. <i>Date of Electronic Publication: </i>2019 Jan 17. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9716531 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-4804 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200222623%22">00222623 </searchLink><i>NLM ISO Abbreviation: </i>J Med Chem <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=30615449 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1021/acs.jmedchem.8b01305 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1231 Titles: – TitleFull: Design of Novel Inhibitors of Human Thymidine Phosphorylase: Synthesis, Enzyme Inhibition, in Vitro Toxicity, and Impact on Human Glioblastoma Cancer. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: de Moura Sperotto ND – PersonEntity: Name: NameFull: Deves Roth C – PersonEntity: Name: NameFull: Rodrigues-Junior VS – PersonEntity: Name: NameFull: Ev Neves C – PersonEntity: Name: NameFull: Reisdorfer Paula F – PersonEntity: Name: NameFull: da Silva Dadda A – PersonEntity: Name: NameFull: Bergo P – PersonEntity: Name: NameFull: Freitas de Freitas T – PersonEntity: Name: NameFull: Souza Macchi F – PersonEntity: Name: NameFull: Moura S – PersonEntity: Name: NameFull: Duarte de Souza AP – PersonEntity: Name: NameFull: Campos MM – PersonEntity: Name: NameFull: Valim Bizarro C – PersonEntity: Name: NameFull: Santos DS – PersonEntity: Name: NameFull: Basso LA – PersonEntity: Name: NameFull: Machado P IsPartOfRelationships: – BibEntity: Dates: – D: 14 M: 02 Text: 2019 Feb 14 Type: published Y: 2019 Identifiers: – Type: issn-electronic Value: 1520-4804 Numbering: – Type: volume Value: 62 – Type: issue Value: 3 Titles: – TitleFull: Journal of medicinal chemistry Type: main |
| ResultId | 1 |
