Design of Novel Inhibitors of Human Thymidine Phosphorylase: Synthesis, Enzyme Inhibition, in Vitro Toxicity, and Impact on Human Glioblastoma Cancer.
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| Title: | Design of Novel Inhibitors of Human Thymidine Phosphorylase: Synthesis, Enzyme Inhibition, in Vitro Toxicity, and Impact on Human Glioblastoma Cancer. |
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| Authors: | de Moura Sperotto ND, Deves Roth C, Rodrigues-Junior VS, Ev Neves C, Reisdorfer Paula F; Laboratório de Desenvolvimento e Controle de Qualidade em Medicamentos , Universidade Federal do Pampa , 97508-000 Uruguaiana , RS , Brazil., da Silva Dadda A, Bergo P, Freitas de Freitas T, Souza Macchi F, Moura S; Laboratório de Produtos Naturais e Sintéticos, Instituto de Biotecnologia , Universidade de Caxias do Sul , 95070-560 Caxias do Sul , RS , Brazil., Duarte de Souza AP, Campos MM, Valim Bizarro C, Santos DS, Basso LA, Machado P |
| Source: | Journal of medicinal chemistry [J Med Chem] 2019 Feb 14; Vol. 62 (3), pp. 1231-1245. Date of Electronic Publication: 2019 Jan 17. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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