Dual blockade of CXCL12-CXCR4 and PD-1-PD-L1 pathways prolongs survival of ovarian tumor-bearing mice by prevention of immunosuppression in the tumor microenvironment.
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| Title: | Dual blockade of CXCL12-CXCR4 and PD-1-PD-L1 pathways prolongs survival of ovarian tumor-bearing mice by prevention of immunosuppression in the tumor microenvironment. |
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| Authors: | Zeng Y; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA., Li B; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA., Liang Y; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA., Reeves PM; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA., Qu X; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA., Ran C; Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA; and., Liu Q; National Key Laboratory of Medical Immunology, Second Military Medical University, Shanghai, China., Callahan MV; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA., Sluder AE; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA., Gelfand JA; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA., Chen H; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA., Poznansky MC; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA. |
| Source: | FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2019 May; Vol. 33 (5), pp. 6596-6608. Date of Electronic Publication: 2019 Feb 25. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 30802149 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Dual blockade of CXCL12-CXCR4 and PD-1-PD-L1 pathways prolongs survival of ovarian tumor-bearing mice by prevention of immunosuppression in the tumor microenvironment. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Zeng+Y%22">Zeng Y</searchLink>; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Li+B%22">Li B</searchLink>; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Liang+Y%22">Liang Y</searchLink>; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Reeves+PM%22">Reeves PM</searchLink>; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Qu+X%22">Qu X</searchLink>; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Ran+C%22">Ran C</searchLink>; Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA; and.<br /><searchLink fieldCode="AU" term="%22Liu+Q%22">Liu Q</searchLink>; National Key Laboratory of Medical Immunology, Second Military Medical University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Callahan+MV%22">Callahan MV</searchLink>; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Sluder+AE%22">Sluder AE</searchLink>; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Gelfand+JA%22">Gelfand JA</searchLink>; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Chen+H%22">Chen H</searchLink>; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Poznansky+MC%22">Poznansky MC</searchLink>; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228804484%22">FASEB journal : official publication of the Federation of American Societies for Experimental Biology</searchLink> [FASEB J] 2019 May; Vol. 33 (5), pp. 6596-6608. <i>Date of Electronic Publication: </i>2019 Feb 25. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Federation+of+American+Societies+for+Experimental+Biology%22">Federation of American Societies for Experimental Biology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8804484 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1530-6860 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208926638%22">08926638 </searchLink><i>NLM ISO Abbreviation: </i>FASEB J <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=30802149 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1096/fj.201802067RR Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 6596 Titles: – TitleFull: Dual blockade of CXCL12-CXCR4 and PD-1-PD-L1 pathways prolongs survival of ovarian tumor-bearing mice by prevention of immunosuppression in the tumor microenvironment. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Zeng Y – PersonEntity: Name: NameFull: Li B – PersonEntity: Name: NameFull: Liang Y – PersonEntity: Name: NameFull: Reeves PM – PersonEntity: Name: NameFull: Qu X – PersonEntity: Name: NameFull: Ran C – PersonEntity: Name: NameFull: Liu Q – PersonEntity: Name: NameFull: Callahan MV – PersonEntity: Name: NameFull: Sluder AE – PersonEntity: Name: NameFull: Gelfand JA – PersonEntity: Name: NameFull: Chen H – PersonEntity: Name: NameFull: Poznansky MC IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: 2019 May Type: published Y: 2019 Identifiers: – Type: issn-electronic Value: 1530-6860 Numbering: – Type: volume Value: 33 – Type: issue Value: 5 Titles: – TitleFull: FASEB journal : official publication of the Federation of American Societies for Experimental Biology Type: main |
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